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X-tosis Receives Grant from The Michael J. Fox Foundation to Advance Novel Parkinson’s Disease Therapy

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Gainesville, United States, June 23rd, 2026, FinanceWire

X-tosis Receives Grant from The Michael J. Fox Foundation for Parkinson’s Research to Advance Novel Parkinson’s Disease Therapy. The ward supports advancement of X-tosis’s mitochondrial approach and accelerates development of its lead Parkinson’s candidate toward the clinic.

X-tosis, Inc., a precision-medicine biotechnology company founded in 2024 and dedicated to developing novel mitochondrial therapeutics for neurodegenerative diseases, today announced it has been awarded a $2.74 million grant from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) through its Parkinson’s Disease Therapeutics Pipeline Program. The funding will support advancement of XTS001, the lead candidate from the company’s MitoXTS platform, a patented family of small-molecule inhibitors of voltage-dependent anion channel 1 (VDAC1) oligomerization, toward clinical development for the treatment of Parkinson’s disease (PD). The grant was awarded following a competitive peer-review process evaluating scientific innovation and translational potential.

The MJFF Parkinson’s Disease Therapeutics Pipeline Program accelerates promising PD therapies from preclinical to clinical stages by supporting innovative approaches that address core disease mechanisms.

XTS001 is a brain-penetrant, orally available small molecule designed to selectively inhibit VDAC1 oligomerization, a pathological process increasingly recognized as a central driver of mitochondrial failure, neuroinflammation, and neuronal loss in PD. Preclinical studies in animal models of PD and AD across the MitoXTS platform have demonstrated reduced dopaminergic neuron loss, restoration of dopamine levels, and protection against key PD-associated pathologies through preservation of mitochondrial function and prevention of apoptosis triggered by cellular stressors.

“This grant from MJFF is a major milestone for X-tosis and represents a strong validation of our MitoXTS approach to addressing unmet needs in Parkinson’s and other neurodegenerative diseases,” said Yotam Nisemblat, Chief Scientific Officer of X-tosis and Principal Investigator on the project. “By preserving mitochondrial integrity upstream in the neurodegeneration cascade, we aim to shift treatment from symptomatic relief to targeting underlying disease biology. We are grateful for MJFF’s support to advance confirmatory studies, biomarker development, and IND-enabling work.”

“This award from The Michael J. Fox Foundation is more than funding; it is support for further investigation of our scientific approach that mitochondrial dysfunction is a central addressable driver of Parkinson’s disease,” said Erin Henderson, CEO of X-tosis, Inc. “We believe XTS-001 represents a first-in-class opportunity to intervene upstream in the neurodegenerative cascade, potentially transforming the treatment paradigm from symptomatic management to targeting disease biology.. With MJFF’s support, we are accelerating toward IND-enabling studies and positioning XTS001 as a potential therapeutic approach for Parkinson’s disease and beyond.”

X-tosis’s MitoXTSTM platform is built upon more than five decades of pioneering research by Professor Varda Shoshan-Barmatz, PhD, a global leader in mitochondrial biology and VDAC1 specifically. Her groundbreaking work established VDAC1 as a central regulator of mitochondrial function and apoptosis, with direct implications for neurodegenerative diseases. With over 225 publications, more than 14,000 citations, and multiple patents covering VDAC1-targeted therapeutics, her discoveries form the scientific foundation of X-tosis’s pipeline.

X-tosis plans to leverage the grant to achieve key development milestones and position XTS001 for clinical trials. If successful, this work could contribute to the development of therapies with the potential to slow disease progression and improve outcomes for millions worldwide. Beyond Parkinson’s disease, the MitoXTS platform is being advanced across multiple neurodegenerative indications, positioning X-tosis with a diversified pipeline of precision mitochondrial therapeutics.

About Parkinson’s Disease

Parkinson’s disease affects more than 10 million people globally and currently lacks approved disease-modifying therapies.

About X-tosis, Inc.

X-tosis, Inc. is a Gainesville, FL-based biotechnology company developing first-in-class mitochondrial therapeutics via the patented MitoXTS platform. By modulating VDAC1 oligomerization to restore mitochondrial health, reduce inflammation, and prevent neuronal death, X-tosis aims to transform treatment for Alzheimer’s, Parkinson’s, ALS, and related conditions. For more information, visit www.x-tosis.com.

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CEO
Erin Henderson
X-tosis
info@x-tosis.com

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Coinbunch Launches Specialist Crypto Tax Reporting and Accounting Service for Individuals and Institutions

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United Arab Emirates, 25th Aug 2026 — Coinbunch, a licensed and registered financial institution, today announced the launch of its crypto tax reporting, transaction reconciliation, and accounting service for individuals and institutions whose digital asset holdings are too fragmented, technical, or spread across jurisdictions for conventional tax preparers and generic tax software to handle correctly.

Crypto holders with activity spanning multiple exchanges, wallets, and chains routinely run into the same problem: cost basis is fragmented or missing, some exchanges have closed or stopped providing records, and on-chain activity such as staking, lending, liquidity provision, and bridging falls outside what most preparers can interpret. Generic tax software compounds the issue by frequently misreading transfers between a client’s own wallets and exchanges as taxable disposals, inflating reported gains and producing schedules that do not reflect what actually happened.

Coinbunch’s service is built specifically around these failure points. The desk reconstructs cost basis from on-chain data, partial exports, and bank records; identifies and reconciles self-transfers so they are removed from the disposal schedule; classifies DeFi and on-chain income into the correct tax treatment; and prepares multi-year catch-up filings for clients whose earlier returns were never filed or were filed incompletely. Every filing-ready schedule is delivered with supporting working papers that trace each figure back to its source records. A parallel accounting line of service provides bookkeeping and financial statement preparation for individuals, funds, and entities holding digital assets, built from the same reconciled data where clients engage the desk for both.

Every engagement follows the same structure: a confidential scoping call to assess the client’s holdings, jurisdictions, and entity type; a written scope of work and a fixed fee delivered before any work begins; and execution in which transactions are matched, cost basis is rebuilt, and gaps are flagged for the client’s review before any figure is finalized. Data collection is read-only throughout — Coinbunch never requests private keys, seed phrases, or transfer authority.

The firm reports a track record spanning more than 30 jurisdictions and hundreds of engagements, all delivered on a fixed-fee basis with no hourly billing. Clients range from individual traders and long-term holders with years of complex or unfiled history, to family offices, funds, corporate treasuries, and DeFi participants whose on-chain activity requires specialist classification.

“I have spent the past 12 years practicing tax law and the past eight working in cybersecurity. Both fields reward the same habits: precision, patience, and a willingness to sit with a problem until it is properly understood. That is the mindset we brought to Coinbunch,” said Joachim, Founder and CEO of Coinbunch.

Coinbunch confirms client eligibility before any onboarding begins, assessing jurisdiction, entity type, source of funds, and identity verification. The firm does not serve every country and directs prospective clients to confirm coverage before starting a scoping call. Coinbunch does not hold, move, or transact client assets, and has warned that any party claiming to recover blockchain funds on the firm’s behalf is fraudulent.

Coinbunch is available now for scoping calls at coinbunch.com, with a written scope of work and fixed fee provided after each confidential consultation.

About Coinbunch

Coinbunch Inc. is a licensed and registered financial institution and a Domestic Business Corporation registered in Albany, New York. The firm provides crypto tax reporting, transaction reconciliation, tax advice, bookkeeping, and financial statement preparation for private and institutional holders of digital assets, with services covering cost basis reconstruction, transfer reconciliation, multi-year catch-up filings, and filing-ready reporting backed by traceable working papers. Coinbunch is led by Founder and CEO Joachim, who brings 12 years of tax law practice and 8 years in cybersecurity, including prior roles at Microsoft, Barclays, and Cisco. More information is available at coinbunch.com.

Media Contact

Organization: Coinbunch Inc

Contact Person: Joachim Holdinghausen

Website: https://coinbunch.com/

Email: Send Email

Country:United Arab Emirates

Release id:48373

The post Coinbunch Launches Specialist Crypto Tax Reporting and Accounting Service for Individuals and Institutions appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section

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K-Beauty Brand HANDAM Launches Hydration-Focused Skincare Inspired by Korean Nature

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The Everyall Co., Ltd. introduces a three-product skincare collection centered on hydration, sensory textures, and ingredients inspired by Korea’s natural environment.

Wonju-si, South Korea, 24th Aug 2026 — Korean skincare brand HANDAM, developed by The Everyall Co., Ltd., launches its first skincare collection with a hydration-focused approach inspired by the purity and calm of Korean nature.

HANDAM expresses the idea of “holding and preserving beauty,” bringing together nature-inspired ingredients, modern skincare formulations, and a refined sensory experience designed to support balanced, healthy-looking skin.

At the center of the collection is Jeju Lava Seawater, a natural ingredient sourced from Jeju Island, combined with Aquaxyl™, a Centella Asiatica complex, Panthenol, and other skin-conditioning ingredients. The collection is designed around hydration and comfortable daily use, with textures created to feel fresh, lightweight, and easy to layer.

Three Products, One Hydration Ritual

  • HANDAM Hydrating Serum: A lightweight cream-in-serum formula featuring Rosa Rugosa Extract. It is designed to deliver a refreshing layer of hydration with a smooth, non-sticky finish.
  • HANDAM Hydrating Cream: A moisturizer inspired by a melting sherbet texture. The formula melts smoothly into the skin and leaves a fresh, moisturized finish without feeling heavy.
  • HANDAM Hydrating Sunscreen: A daily sunscreen developed with a moisturizing texture that feels comfortable on the skin and is designed to layer well under makeup.

A Sensory Approach to Hydration 

Rather than focusing on hydration as a single functional claim, HANDAM approaches it as a daily skincare experience. The serum, cream, and sunscreen are designed to complement one another through different textures and stages of a routine, allowing users to layer hydration without an overly heavy or sticky finish.

“Modern consumers are looking for skincare products that offer not only thoughtfully selected ingredients but also a comfortable sensory experience,” said a representative of The Everyall Co., Ltd. “Through HANDAM, we aim to translate the purity of Korean nature into a contemporary hydration ritual that feels simple, refined, and enjoyable in everyday life.”

Positioning HANDAM for Global K-Beauty Consumers 

As global interest in K-Beauty continues to expand, HANDAM plans to introduce its hydration-focused skincare philosophy to international consumers and expand its presence in global markets. The brand will position its first collection around a clear combination of storytelling inspired by Korean nature, modern formulations, and distinctive textures.

HANDAM’s debut collection marks the first step in building a broader skincare identity centered on hydration, comfort, and a contemporary interpretation of Korean beauty.

About HANDAM 

HANDAM is a Korean skincare brand developed by The Everyall Co., Ltd. The brand focuses on hydration-centered skincare inspired by Korean nature, combining carefully selected ingredients with modern textures and refined sensory experiences.

For more information, please visit https://handamstore.com/

Media Contact

Organization: The Everyall Co., Ltd.

Contact Person: Kim chong won

Website: https://handamstore.com/

Email: Send Email

City: Wonju-si

Country:South Korea

Release id:48371

The post K-Beauty Brand HANDAM Launches Hydration-Focused Skincare Inspired by Korean Nature appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section

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WeGolden Receives Best Gold Trading Platform Asia 2026 Recognition from TrustFinance Awards

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Singapore, Singapore, August 24th, 2026, FinanceWire

WeGolden has received the Best Gold Trading Platform Asia 2026 recognition from the TrustFinance Performance Awards, highlighting its gold-focused trading environment, platform capabilities, and accessibility across supported Asian markets.

The recognition forms part of the TrustFinance Performance Awards 2026, which recognizes companies across specific areas of performance based on category-relevant assessment. Evaluations may consider company submissions, supporting materials, publicly available information, and other evidence relevant to the respective award category.

For Best Gold Trading Platform Asia 2026, the recognition centers on WeGolden’s gold-focused offering and the broader platform experience surrounding it.

Gold is a central part of WeGolden’s trading offering. The platform provides access to gold alongside other global financial instruments through MetaTrader 5 (MT5), enabling users to access multiple asset classes within an established trading environment. WeGolden also provides real-time market information and charting resources to help users follow market movements and support their trading decisions.

Beyond its core trading infrastructure, WeGolden offers copy trading functionality, allowing users to explore strategy providers, review available performance information, and monitor trading activity. Combined with market analysis and educational resources, these capabilities form part of a broader platform experience designed to accommodate different levels of trading experience and approaches to the market.

WeGolden also provides localized digital experiences in several Asian languages, including Thai, Indonesian, Filipino, and Hindi. The platform supports a range of payment methods and local deposit and withdrawal options for users in supported markets, further extending the accessibility of its services across the region.

“A strong gold trading platform is defined by more than access to a single instrument. Trading infrastructure, market information, supporting tools, and accessibility all contribute to the overall experience. WeGolden has developed an approach that brings these elements together within a gold-focused trading environment for users across supported Asian markets,” said Peter Bu, CEO of TrustFinance.

The Best Gold Trading Platform Asia 2026 recognition reflects WeGolden’s continued development of a gold-focused trading environment supported by established trading infrastructure, market tools, copy trading capabilities, and localized services across supported markets in Asia.

About WeGolden

WeGolden is an online trading platform with a strong focus on gold, providing access to a range of financial instruments including forex, metals, indices, energies, cryptocurrencies, and share CFDs. The platform provides access to MetaTrader 5 alongside market information, copy trading functionality, educational resources, and account services designed to support the overall trading experience.

For more information, visit www.wegolden.com

About TrustFinance Awards

TrustFinance Awards is an independent recognition program focused on performance and achievement across the global financial industry. Through the TrustFinance Performance Awards, companies are evaluated within specific areas of performance using category-relevant criteria. Evaluations may consider publicly available information, company submissions, and supporting evidence relevant to each award category.

The program recognizes performance across areas including customer experience, transparency, technology, innovation, platform capabilities, and operational excellence.

For more information, visit awards.trustfinance.com

Disclaimer: This award recognition is based on the TrustFinance Awards evaluation criteria for the specified category and period. It does not constitute financial advice, investment advice, or a recommendation of any financial product or service.

Contact

TrustFinance Awards
TrustFinance
awards@trustfinance.com

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Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.

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