Press Release
New Clinical Data Reveals MAIA Biotechnology’s THIO Achieves High Efficacy In Advanced Non-Small Cell Lung Cancer Treatment
–News Direct–
By Mangeet Kaur Bouns
Lung cancer remains the top cause of cancer-related deaths in the U.S., accounting for approximately 20% of all cancer fatalities. The American Cancer Society's projections for 2024 highlight the gravity of this issue, with an estimated 234,580 new lung cancer cases and about 125,070 deaths anticipated in the U.S. Of these, nearly 80% to 85% are non-small cell lung cancer (NSCLC) cases, highlighting the urgent need for effective treatments.
MAIA Biotechnology, Inc. (AMEX: MAIA), a clinical-stage biopharmaceutical company focused on developing telomere-targeting immunotherapies for cancer treatment, has unveiled promising new clinical data showcasing the efficacy of its lead product candidate, THIO, in treating NSCLC. This data emerges from a phase 2 clinical trial evaluating THIO in combination with the immune checkpoint inhibitor (CPI) cemiplimab (Libtayo), targeting patients with advanced NSCLC who have not responded to at least two standard-of-care therapies.
In the context of NSCLC, where traditional treatments often fall short, THIO's potential as a first-in-class telomere-targeting agent raises hope. Its ability to disrupt cancer cell telomeres and stimulate immune responses marks a significant advancement in the fight against this devastating disease.
MAIAs Lead Candidate: THIO
THIO is a groundbreaking telomere-targeting agent, currently undergoing phase 2 clinical trials aimed at treating NSCLC with telomerase-positive cancer cells. Telomerase, present in over 85% of human cancers, plays a crucial role in the immortality and proliferation of cancer cells. THIO integrates into telomeres within these cells, disrupting their structure and function leading to rapid tumor cell death.
By inducing telomerase-dependent DNA modification and damage, THIO triggers selective cancer cell death. This process accumulates telomeric damage in cytosolic micronuclei, which then activates both innate (cGAS/STING) and adaptive (T-cell) immune responses. In in vivo cancer models, sequential treatment with THIO followed by PD-(L)1 inhibitors resulted in significant and sustained tumor regression, fostering cancer-specific immune memory.
Key Findings From The Phase 2 THIO-101 Clinical Trial
The phase 2 THIO-101 trial primarily focuses on assessing the safety and tolerability of THIO both as an anticancer agent and as an immune system activator, alongside evaluating its clinical efficacy through overall response rate (ORR).
The trial results are noteworthy. The disease control rate (DCR) for THIO in combination with CPI was 85%, far exceeding the 25-35% DCR typically seen with chemotherapy in third-line treatments. Additionally, 65% of patients surpassed the 5.8-month overall survival (OS) threshold, and 85% exceeded the 2.5-month progression-free survival (PFS) threshold, demonstrating significant clinical benefits. The median survival follow-up time stood at 9.1 months for the cohort of 20 patients.
Optimal dose selection yielded even more impressive outcomes. Patients in third-line receiving 180mg of THIO exhibited a median PFS of 5.5 months, a 75% OS rate at six months and an ORR of 38%, compared to the standard 6-10% ORR for chemotherapy. Notably, 75% of these patients crossed the 5.8-month OS threshold and 88% surpassed the 2.5-month PFS threshold, with a median survival follow-up time of 9.1 months among the eight patients assessed.
Implications And Future Directions
Dr. Vlad Vitoc, chairman and CEO of MAIA, expressed enthusiasm about the trial outcomes, noting, "All exceptional measures of efficacy in our trial to date have exceeded our own expectations and outperformed standard-of-care treatments." He emphasized THIOs potential as a robust, safe and highly effective alternative for patients who have not benefited from chemotherapy and other treatments.
The THIO-101 trial, which completed enrollment ahead of schedule in February, reached its target of 41 patients for the 180 mg dose. This data, which indicates promising disease control and overall response rates, paves the way for further investigation and potential redefinition of cancer treatment protocols.
As THIO-101 data continues to demonstrate favorable disease control and response rates, with full efficacy data anticipated in the latter half of this year, MAIA Biotechnology stands poised to redefine cancer treatment. THIOs promise to transform the standard of care in oncology offers new hope to patients with advanced NSCLC, potentially establishing a new benchmark in cancer therapy.
Featured photo by CI Photos at Shutterstock.
Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders.
This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice.
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Press Release
WHY VANESSA HUDGENS CHOSE AMAZON’S EKOUAER OVER LUXURY LABELS — AND WHAT IT REVEALS ABOUT FASHION’S NEW ERA
New York, US / Timesnewswire / October 2, 2026 – For decades, A-list celebrity endorsements followed a predictable blueprint: high fashion, multi-million-dollar haute couture deals, and unattainable luxury. But this fall, Hollywood star Vanessa Hudgens is continuing her game-changing fashion narrative with Amazon’s sleepwear and loungewear giant, EKOUAER.
First announced as an official EKOUAER Brand Friend earlier this July, Hudgens’ collaboration with the brand hits a major crescendo this October as EKOUAER celebrates its 11th Anniversary. Rather than aligned with exclusive runaway brands, Hudgens has embraced the ultimate daily wardrobe staple used by millions of everyday women across America.
“Becoming a mom has definitely made me appreciate versatility even more,” says Vanessa Hudgens. “I want pieces that are comfortable and easy for everyday life, but that I can dress up and still feel really good in.”
As EKOUAER marks its 11-year milestone, the timing coincides with October’s major Amazon shopping moment, proving that “everyday comfort” is officially beating traditional luxury status symbols. The star’s fall favorites spotlight pieces engineered for multi-scenario living, including the viral Ekouaer Satin Pajamas Set with Bow Tie Front and and the versatile, ultra-cozy Ekouaer 2-Piece Pleated Lounge & Sweater Set. “For me, it’s about finding that sweet spot where you feel comfortable but still put together,” Hudgens adds. “I love being able to take the same piece and completely change the feeling of it depending on how I style it.”
As EKOUAER kicks off its 11th Anniversary celebrations, the alliance redefines modern celebrity style: luxury isn’t about the price tag—it’s about effortless comfort.
EKOUAER
Dana Li
New York, US
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Press Release
From One Store to 400 Daily Orders: 70-Year-Old Lalit Kumar Takes Natural Spices Online Across UAE
The Indian-born businessman has lived and worked in the UAE since 1983. Now 70, he has taken a single grocery store online, and it handles around 400 orders a day.
Dubai, Al Nahda 1, United Arab Emirates, 2nd Oct 2026 – When shipments were getting stuck and many small shops decided to sit tight, Lalit Kumar did the opposite. At 70, the owner of Natural Spices and Foodstuff Trading LLC moved his grocery business online. Today it delivers to customers in every emirate.
He started with one retail outlet and five staff. The business now handles about 400 orders a day through its own website, NaturalSpicesUAE.com, and through the UAE’s major online marketplaces. It sells spices, herbs, Indian groceries, snacks, dry fruits and other daily essentials.
Forty Years in the UAE
Mr. Kumar came to the UAE from India in 1983. Since then he has run businesses in electronics, transport, and oil and gas, and now in foodstuff. He says each one prepared him for the next. Electronics taught him how customers think. Transport taught him about timing. Oil and gas taught him patience.
“I came here as a young man and this country gave me a chance. It gave my family a home. I have never taken that for granted, and everything I build here is my way of saying thank you.”
— Lalit Kumar, Owner, Natural Spices and Foodstuff Trading LLC
Moving When Others Waited
The shift online came at a hard time for retail. Deliveries were running late, costs were going up and fewer people were walking into shops. Mr. Kumar decided not to wait it out.
With his team of five, he set up online ordering, reorganised the stock and worked out packing and delivery, all from the same store they were already running. The website went live, the products went onto the marketplaces, and orders started coming in from across the country.
“I have seen this market go up and down many times since 1983. If you stop every time things get difficult, you will never move. At my age people expect me to slow down. I would rather see what comes next.”
— Lalit Kumar
Still in the Store Every Day
Orders now go out to Abu Dhabi, Dubai, Sharjah, Ajman, Umm Al Quwain, Ras Al Khaimah and Fujairah. Customers say they come back for the range, the fair prices and delivery they can count on.
Growth hasn’t pulled Mr. Kumar away from the business. He is in the store every day. He talks to customers himself, bargains with suppliers and makes the big decisions. His staff say he has more energy than most of them, and he still knows many of his regulars by name.
“A customer is a person, not an order number. Whether they walk into the shop or order from Fujairah, they should get the same respect and the same fair price. That is how I have always worked. A website doesn’t change that.”
— Lalit Kumar
Looking Ahead
Over the coming months, the company plans to add more products, grow its marketplace presence and improve delivery across the UAE.
“I have been building businesses in this country for more than forty years, and I still feel like I’m starting out. As long as I have the energy, I’ll keep going, for my customers, my team and for the UAE.”
— Lalit Kumar
About Natural Spices and Foodstuff Trading LLC
Natural Spices and Foodstuff Trading LLC is a UAE-based grocery and foodstuff company serving customers through its retail outlet, its e-commerce platform NaturalSpicesUAE.com and leading online marketplaces across the United Arab Emirates. The company offers spices, herbs, Indian grocery products, snacks, dry fruits and other food essentials. It is owned and led by Lalit Kumar, who has been in business in the UAE since 1983 across the electronics, transport, oil and gas, and foodstuff sectors.
Media Contact
Organization: Natural Spices and Foodstuff Trading LLC
Contact Person: Lalit Kumar Kundani
Website: https://naturalspicesuae.com/
Email: Send Email
Contact Number: +971529941656
Address: Al Bannai Building, Shop 1, Al Amman Street, Al Nahda 1, Dubai, UAE
City: Dubai
State: Al Nahda 1
Country: United Arab Emirates
Release id: 45332
The post From One Store to 400 Daily Orders: 70-Year-Old Lalit Kumar Takes Natural Spices Online Across UAE appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section
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Press Release
Memito Opens Token Sale on Ethereum With Formula-Based Pricing and Multi-Network Payments
Memito, a community meme token on Ethereum, has opened a token sale on memito.org. The price is calculated by a formula in the verified smart contract, and the sale accepts five assets on Ethereum, a bridge from five networks and a wide range of wallets.
Canada, 2nd Oct 2026 – Memito (MEMITO), a community meme token on Ethereum, has opened its public token sale at memito.org, making participation available worldwide in 24 languages, with five payment assets, a built-in bridge from five networks and support for seven popular wallets. The sale is run directly by the token’s smart contract, which is published and verified on Etherscan.
Formula-based pricing set in the contract
Instead of fixed sale rounds, the token price is calculated by a formula written into the smart contract. The formula starts at 0.00000018585 USD per token and adjusts the price according to the total amount raised in the sale. Before confirming a transaction, each participant is shown the calculated quote for the selected amount. Tokens are transferred to the participant’s wallet within the same on-chain transaction, so there is no separate claim step. Trading of the token has not opened, and no date has been set.
Payment options across networks
The sale accepts ETH, USDT, USDC, DAI and WBTC on Ethereum, with individual transactions from about 1 USD to 10,000 USD. For users whose funds are held on BNB Chain, Arbitrum, Base, Polygon or Optimism, the website integrates the third-party LI.FI bridge, which can move funds to ETH on Ethereum and shows the route fees before signing. The website is available in 24 languages.
The sale page supports MetaMask, Trust Wallet, OKX Wallet, Bitget Wallet, Binance Wallet and Bybit Wallet (via WalletConnect), as well as other WalletConnect-compatible wallets, on desktop and mobile devices.
“Memito started as a meme, but we are building it as a community first,” the Memito team said. “We wanted anyone, from any network and in their own language, to be able to join from day one, with the rules of the sale written openly into the contract. The community on X and Telegram is where we share every next step.”
Token details
The token contract address is 0xe02AD79732658a2ec2C85Ecd15De5E08A311373C. Maximum supply is 420,690,000,000,000 MEMITO. When trading opens, the final supply is allocated as follows: 60% to buyers, referrals and the liquidity pool, 10% to a reserve, 15% to the founder share held in the project’s Ecosystem Wallet and 15% to the treasury. The deploying wallet received no tokens at launch.
About Memito
Memito (MEMITO) is a community meme token (ERC-20) on Ethereum, distributed through a formula-priced token sale on memito.org. More information is available on the project website and on its X and Telegram channels.
The token sale is open now at memito.org, where participants can review the contract details and the current quote before taking part.
Website: memito.org | X: @MEMITO_COIN | Telegram: t.me/memito_coin
Disclaimer: This press release is provided for information purposes only and is not investment advice. Crypto-assets carry risk, including the loss of funds. Readers should do their own research.
Media Contact
Organization: Memito
Contact Person: Memito Team
Website: https://memito.org
Email: Send Email
Country: Canada
Release id: 49614
The post Memito Opens Token Sale on Ethereum With Formula-Based Pricing and Multi-Network Payments appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section
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WHY VANESSA HUDGENS CHOSE AMAZON’S EKOUAER OVER LUXURY LABELS — AND WHAT IT REVEALS ABOUT FASHION’S NEW ERA
From One Store to 400 Daily Orders: 70-Year-Old Lalit Kumar Takes Natural Spices Online Across UAE
Memito Opens Token Sale on Ethereum With Formula-Based Pricing and Multi-Network Payments
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