Press Release
Candel Therapeutics (NASDAQ: CADL) Lead Candidate CAN-2409 Combats Lung, Pancreatic And Prostate Cancers With Fast Track Designation For Three Cancers
–News Direct–
By Jeremy Golden, Benzinga

Immunotherapy has transformed the way cancer is treated, but just 20% to 40% of patients typically respond to FDA-approved immune checkpoint inhibitor (ICI) treatments.
Poor ICI treatment response has been linked to the tumors ability to disguise antigen presentation and generate an immunosuppressive microenvironment. In addition, most conventional immunotherapies are not designed to educate the patients immune system on how to recognize a variety of tumor antigens and neoantigens.
Amid this landscape, a clinical-stage biopharmaceutical company has developed a new multimodal biological approach that leverages the ability of viral gene constructs to activate cancer-killing mechanisms, exposing multiple tumor antigens to the immune system, resulting in vaccination against the tumor while inhibiting the immunosuppressive tumor microenvironment.
Candel Therapeutics, Inc. (NASDAQ: CADL) is developing a product candidate that is being studied in lung, pancreatic and prostate cancers. Candels most advanced viral immunotherapy candidate, CAN-2409, is an investigational off-the-shelf replication-defective adenovirus designed to induce an individualized, systemic immune response against the patients own tumor.
Part of the companys adenovirus platform, CAN-2409 is injected directly into the tumor or target tissue using a localized injection, akin to the standard approach for vaccination.
CAN-2409's adenoviral construct serves as a vector to transport the HSV-thymidine kinase gene into tumor cells at the site of injection. These tumor cells can then express HSV-thymidine kinase, which converts generic, FDA-approved anti-herpes drugs such as ganciclovir, acyclovir and valacyclovir into a toxic nucleotide analog that blocks DNA synthesis in dividing cells.
Cancer cells exposed to the toxic nucleotide analog in the tumor microenvironment have been observed to undergo immunogenic cell death. Simultaneously, the adenoviral serotype 5 capsid protein elicits a strong pro-inflammatory signal in the tumor microenvironment, creating the optimal conditions to induce a specific CD8+ T cell-mediated response against the injected tumor and uninjected distant metastases for broad and systemic anti-tumor activity.
CAN-2409 is currently being studied in an open-label, phase 2 clinical trial in non-small cell lung cancer (NSCLC) and in randomized, controlled, blinded phase 2b and phase 3 clinical trials in prostate cancer. The company has recently released very encouraging data for CAN-2409s ability to improve overall survival in non-metastatic pancreatic cancer, with topline overall survival data in non-small cell lung cancer planned for this quarter (Q2 2024) and results from the prostate clinical trials later this year (Q4 2024).
When it comes to NSCLC, the company previously presented data from the phase 2 clinical trial in which patients received two administrations of CAN-2409 plus prodrug. Those patients demonstrated the following:
1) Increased infiltration of CD8+ cytotoxic T cells in the tumor microenvironment, systemic expansion of effector T cells and increased soluble granzyme B levels in peripheral blood;
2) Favorable changes in the trajectory of tumor progression;
3) Decreased tumor size of target lesions in most patients; and
4) Reduced size of uninjected tumor lesions.
The CAN-2409 immunotherapy antitumor strategy aims to increase the number of long survivors beyond 10 to 13 months.
As previous work has shown that progressive disease could be converted into stable disease in most patients with non-small cell lung cancer after CAN-2409 treatment, the hypothesis is that this will translate into improved survival.
When it comes to pancreatic cancer, the company reported notable improvements in patients with borderline resectable pancreatic ductal adenocarcinoma (PDAC) after experimental treatment with CAN-2409. The estimated overall survival rate was 71.4% at 24 months in CAN-2409-treated patients versus only 16.7% in the control arm after chemoradiation.
In 2023, CAN-2409 received Fast Track Designation for both non-small cell lung cancer and pancreatic cancer, a validation from the FDA on its potential. CAN-2409 plus valacyclovir in combination with continued PD-1/PD-L1 agents is being evaluated in an ongoing, open-label phase 2 clinical trial in patients with late-stage NSCLC and an inadequate response to anti-PD(L)-1 therapy. In 2024, CAN-2409 also received Orphan Drug Designation from the FDA for CAN-2409 in borderline resectable pancreatic cancer.
In the upcoming year, Candel plans to announce data readouts for the following:
1) Phase 2 topline overall survival (OS) data for CAN-2409 in NSCLC, expected in Q2 2024;
2) Phase 2 topline data for CAN-2409 in low-to-intermediate-risk, localized, non-metastatic prostate cancer, expected in Q4 2024;
3) Phase 3 topline data for CAN-2409 in localized intermediate/high-risk prostate cancer, expected in Q4 2024.
Featured photo by National Cancer Institute on Unsplash.
Candel is a clinical stage biopharmaceutical company focused on developing off-the-shelf multimodal biological immunotherapies that elicit an individualized, systemic anti-tumor immune response to help patients fight cancer. Candel has established two clinical stage multimodal biological immunotherapy platforms based on novel, genetically modified adenovirus and herpes simplex virus (HSV) gene constructs, respectively. CAN-2409 is the lead product candidate from the adenovirus platform and is currently in ongoing clinical trials in non-small cell lung cancer (NSCLC) (phase 2), borderline resectable pancreatic cancer (phase 2), and localized, non-metastatic prostate cancer (phase 2 and phase 3). CAN-3110 is the lead product candidate from the HSV platform and is currently in an ongoing investigator-sponsored phase 1 clinical trial in recurrent high-grade glioma (HGG). Finally, Candels enLIGHTEN Discovery Platform is a systematic, iterative HSV-based discovery platform leveraging human biology and advanced analytics to create new viral immunotherapies for solid tumors.
This article includes certain disclosures that contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, without limitation, express or implied statements regarding the timing and advancement of development programs, including the timing and availability of additional data, key data readout milestones, including CAN-3110 in HGG; expectations regarding the potential benefits conferred by Fast Track Designation; expectations regarding the therapeutic benefit of its programs, including the potential for its programs to extend patient survival; and expectations regarding cash runway and expenditures. The words may, will, could, would, should, expect, plan, anticipate, intend, believe, estimate, predict, project, potential, continue, target and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Any forward-looking statements in this press release are based on managements current expectations and beliefs and are subject to a number of risks, uncertainties and important factors that may cause actual events or results to differ materially from those expressed or implied by any forward-looking statements contained in this press release, including, without limitation, those risks and uncertainties related to the timing and advancement of development programs; expectations regarding the therapeutic benefit of the Companys programs; that final data from our pre-clinical studies and completed clinical trials may differ materially from reported interim data from ongoing studies and trials; the Companys ability to efficiently discover and develop product candidates; the Companys ability to obtain and maintain regulatory approval of product candidates; the Companys ability to maintain its intellectual property; the implementation of the Companys business model, and strategic plans for the Companys business and product candidates, and other risks identified in the Companys SEC filings, including the Companys most recent Quarterly Report on Form 10-Q filed with the SEC, and subsequent filings with the SEC. The Company cautions you not to place undue reliance on any forward-looking statements, which speak only as of the date they are made. The Company disclaims any obligation to publicly update or revise any such statements to reflect any change in expectations or in events, conditions or circumstances on which any such statements may be based, or that may affect the likelihood that actual results will differ from those set forth in the forward-looking statements. Any forward-looking statements contained in this press release represent the Companys views only as of the date hereof and should not be relied upon as representing its views as of any subsequent date.
This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice.
Contact Details
Aljanae Reynolds
+1 617-916-5445
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View source version on newsdirect.com: https://newsdirect.com/news/candel-therapeutics-nasdaq-cadl-lead-candidate-can-2409-combats-lung-pancreatic-and-prostate-cancers-with-fast-track-designation-for-three-cancers-458506267
Candel Therapeutics
COMTEX_453480918/2655/2024-06-07T08:28:02
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Press Release
Malaysia’s AI Future Takes Centre Stage as World AI Show Returns for Its 48th Global Edition
Kuala Lumpur, 13 August 2026, ZEX PR WIRE — Artificial intelligence has moved beyond being an emerging technology to become a defining pillar of Malaysia’s economic and digital ambitions. As the country accelerates investments in AI infrastructure, sovereign cloud capabilities, and enterprise-wide transformation, the focus has shifted from experimentation to execution. Against this backdrop, World AI Show Malaysia returns for its 48th Global Edition on 9–10 September 2026 at DoubleTree by Hilton Kuala Lumpur, Malaysia, convening the policymakers, enterprise leaders, technology pioneers, investors, and innovators who are shaping the country’s next chapter of AI-led growth.
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Presented by Trescon, World AI Show Malaysia carries this year’s tagline, “Where Malaysia’s AI Decisions Get Made.” As the country transitions into a strategic AI hub for Southeast Asia and organisations across both the public and private sectors define their AI roadmaps, modernise digital infrastructure, and establish governance frameworks for responsible innovation, the event will provide an executive platform dedicated to meaningful dialogue, strategic partnerships, and commercially relevant outcomes.
The programme has been curated to address the opportunities and complexities surrounding enterprise AI adoption, sovereign cloud, intelligent infrastructure, cybersecurity, data governance, and responsible AI implementation. Over two days, attendees will engage through keynote addresses, executive panel discussions, fireside conversations, invitation-only boardroom sessions, technology showcases, curated networking engagements, and business meetings designed to facilitate knowledge exchange and cross-sector collaboration.
The conference will feature an impressive line-up of distinguished government and industry leaders, including:
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Budiman Bujang, Deputy Chief Digital Officer, Johor Corporation
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Ts. D. Jackson Raao, Principal Assistant Secretary, Ministry of Science, Technology and Innovation (MOSTI)
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Jamie Tan, Managing Director, JLL Malaysia
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Ganeshbabu Nagarajan, Executive Director – Transformation Programmes, Standard Chartered Bank
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Chua Yong Howe, Chief Digital Officer, UEM Edgenta Berhad
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Shahrin Oli Mohamed, Group Chief Technology Officer, Pos Malaysia Berhad
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Keeratpal Singh, Chief AI and Data Officer (APAC Financial Services), Worldline
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Dr. Sadesh Manikam, Executive Vice President, Enterprise Data Office & Data Protection Officer, Bursa Malaysia
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Ts. Zairil Anuar Ahmad, Chief Technology Officer, Co-opbank Pertama
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Ahmad Faiz, Head – Data & AI, Global Technology Unit, BASF
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Raunak Mehta, Chief Executive Officer, Igloo
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Muhammad Najib Masdan, Senior Vice President, Khazanah Nasional Berhad
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Ts. Narayanan Chidambaram, Head Project Engineering Pod (Technology & Digital PE&T – Digital Project Management) PETRONAS
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Mohamed Aafrin, Director of Engineering, DKSH
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Sudeep Srivastava, Head – KL IT Center SLB (Schlumberger)
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Hong H. Ong, Director of Digital Technology, Labuan Financial Services Authority
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Mohd Hanapi Bisri, Senior Digital Industry Leader- Oil & Gas
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Dario Bianchi, Chief Product Officer, Mindvalley
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G Saravanan, Chief Information Officer, National Cancer Society Malaysia
Reflecting on Malaysia’s AI trajectory, Ts. D. Jackson Raao, Principal Assistant Secretary, MOSTI, said:
“Malaysia is at a pivotal stage where artificial intelligence is becoming a key driver of national transformation. As we accelerate AI adoption across industries, our focus must remain on responsible innovation, robust governance, strong cybersecurity, and developing a future-ready talent ecosystem. By doing so, Malaysia is well-positioned to emerge as a trusted regional leader in safe and sustainable AI innovation.”
An ecosystem of public sector and technology organisations is supporting this year’s edition. CyberSecurity Malaysia joins as the Supporting Partner, reinforcing the importance of building a secure and trusted digital ecosystem.
Datadog joins as the Lead Sponsor, Magure as the Platinum Sponsor, Bitdeer AI as the Gold Sponsor, and Alibaba Cloud and Unison Consulting Sdn Bhd as Bronze Sponsors. The exclusive CXO Boardroom sessions will be powered by Zoom and Datadog, while CloudSpace will participate as an exhibitor, showcasing cloud and AI capabilities to enterprise decision-makers.
Designed exclusively for senior executives, government representatives, and technology leaders, World AI Show Malaysia 2026 will provide a platform where strategic priorities are translated into actionable partnerships, investment opportunities, and real-world AI deployments. As Malaysia continues to strengthen its position within the regional AI landscape, the summit is set to become a key meeting point for organisations shaping the future of intelligent enterprise across Southeast Asia.
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For sponsorship opportunities, speaking engagements, or attendance information, please contact:
Shrikanth Prabhu
Commercial Director
Email: prabhu@tresconglobal.com
Mobile: +91 8660115892
Media Contact:
Reeha Haris
Media & PR Executive
Email: reeha@tresconglobal.com
Mobile: +91 8848655312
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Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
Press Release
Phomemo Expands Tattoo Stencil Printer Solutions to Support Professional Artists Evolving Workflows
New York, New York, United States, 13th Aug 2026 – Phomemo, a global creative printing brand specializing in thermal printing solutions, has expanded its tattoo stencil printer lineup with two new solutions — the Phomemo TA81 Large-Format Tattoo Stencil Printer and Phomemo L85 Smart Touchscreen Tattoo Stencil Printer — designed to support the evolving needs of professional tattoo artists.
From large-scale body art preparation to everyday studio workflows, different tattoo projects require different printing solutions. While some artists prioritize portability and flexibility, others need tools that can handle full-length designs, customized layouts, and more efficient preparation processes.
Alongside established models including the M08F-WS and M08F Plus, Phomemo’s expanded tattoo printer lineup provides artists with multiple options based on their creative style, workflow, and studio needs.

Choosing the Right Tattoo Stencil Printer Matters
For tattoo artists, stencil preparation is an important step between digital design and the final artwork on skin. A reliable tattoo stencil printer can help artists maintain design accuracy, reduce preparation time, and create a smoother workflow before each session.
However, different tattoo styles create different challenges.
Artists specializing in fine details may prioritize clear and portable printing solutions, while those creating sleeves, back pieces, or large-scale compositions often face a different challenge: preparing oversized stencils without manually assembling multiple sections.
Phomemo’s tattoo stencil printer solutions are designed around these different creative scenarios.
Phomemo TA81: A Large-Format Tattoo Stencil Printer Built for Complex Designs

For artists who regularly create full sleeves, back pieces, legs, or other large-scale tattoo projects, stencil preparation can become one of the most time-consuming parts of the workflow.
Traditionally, oversized tattoo designs often require artists to print multiple stencil sheets, trim edges, align different sections, and carefully transfer the assembled design onto the skin. While this approach can work, maintaining accuracy across a large composition can add extra preparation steps and increase the risk of misalignment.
The Phomemo TA81 was designed to address this challenge with continuous, variable-length stencil printing.
Unlike standard sheet-based printing methods, the TA81 uses a roll-fed system that allows artists to print large tattoo designs in one continuous piece. For full sleeves, back pieces, spine designs, or other extended compositions, artists can create a complete stencil without manually cutting and joining multiple sections.
This one-piece printing workflow helps maintain design continuity and makes stencil preparation more efficient for complex tattoo projects.
Beyond size capability, the TA81 focuses on reducing waste during professional workflows. Its variable-length printing system allows artists to print only the required length for each design rather than relying on fixed-size sheets. For busy studios handling multiple projects, this can help optimize transfer paper usage during daily operations.
The TA81 also features Phomemo’s wrinkle-resistant printing technology, designed to help keep transfer paper flat during longer printing processes. Combined with an upgraded print head and edge-stabilizing design, the printer helps deliver consistent and clear stencil lines throughout the entire design.
With Bluetooth and USB connectivity support, the TA81 can connect with smartphones, tablets, laptops, and desktops across Android, iOS, Windows, macOS, and ChromeOS systems, giving artists flexibility when preparing designs.
Through the Phomemo App, artists can adjust designs, preview tattoo layouts, split large images, manage transfer settings, and prepare files before printing.
Phomemo L85: Smart Touchscreen Control for a More Customized Workflow

While large-scale artists may prioritize printing size and efficiency, other tattoo professionals look for a more interactive and customizable stencil preparation experience.
The Phomemo L85 is designed for artists who prefer a smarter workflow with direct control through an integrated touchscreen.
Featuring a 5-inch touchscreen with six language options, the L85 allows artists to manage printing tasks directly from the device. Functions such as template selection, brightness adjustment, print mileage tracking, battery information display, timer settings, sensor calibration, and self-testing can be accessed without relying entirely on another device.
For artists working with different tattoo styles and design formats, flexibility is also important. The L85 supports multiple print sizes, including Letter, A4, B5, A5, and additional width options, allowing artists to prepare different stencil layouts based on their projects.
The L85 also works with the Phomemo App ecosystem, providing creative and editing tools such as image transformation, tattoo extraction, line-art conversion, tattoo preview, and large-image splitting.
Optional AI-assisted features, including AI image generation and tattoo extraction, are designed to support artists during the preparation stage by helping explore ideas, refine concepts, and improve workflow efficiency — while keeping the artist’s own creativity and craftsmanship at the center of the design process.
Portable Tattoo Stencil Solutions: M08F-WS and M08F Plus

For artists who prioritize mobility, Phomemo also offers portable tattoo stencil printer solutions designed for flexible everyday workflows.
The Phomemo M08F-WS provides a lightweight wireless printing solution for artists who need a compact setup. Supporting Bluetooth connectivity and multiple operating systems, it allows artists to prepare tattoo stencils from smartphones, tablets, laptops, and desktops.
The Phomemo M08F Plus builds on this portable concept with a smarter touchscreen experience. Its built-in touchscreen supports functions including brightness adjustment, auto shutdown, calibration, and self-test printing, helping artists complete basic operations directly from the printer.
With thermal printing technology, both models eliminate the need for ink cartridges while providing a convenient solution for tattoo stencil preparation. Through the Phomemo App, artists can access editing tools, stencil generation, previews, and other workflow features designed to simplify the transition from digital artwork to physical stencil.
Choosing the Right Phomemo Tattoo Stencil Printer
Every tattoo artist has a different creative workflow, and the ideal tattoo stencil printer depends on the type of work being created. All can be found on Phomemo’s official site.
Artists working on large-scale compositions such as sleeves and back pieces may benefit from the Phomemo TA81’s continuous full-length printing capability.
Artists looking for a smart, customizable printing experience can explore the Phomemo L85 with touchscreen control and flexible print options.
Artists who need a portable solution for everyday stencil preparation can choose between the lightweight M08F-WS and the upgraded M08F Plus.
By developing tattoo stencil printers for different artistic scenarios, Phomemo continues to help tattoo professionals simplify preparation, improve efficiency, and focus more on the creative process.
About Phomemo
Phomemo is a global creative printing brand dedicated to making everyday printing simple, enjoyable, and accessible. Backed by over 12 years of expertise in thermal printing technology and trusted by over 40 million users worldwide, Phomemo continues to develop the evolution of smart printing. From home organization to global e-commerce, Phomemo lowers the barrier to professional results, enabling ideas and commerce to flow freely.
Media Contact
Organization: Phomemo
Contact Person: Alicia Chen
Website: https://phomemo.com
Email:
influencerscenter@phomemo.com
City: New York
State: New York
Country:United States
Release id:48084
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Press Release
SBCFX to Showcase Trading Innovation, Regional Growth Strategy, and Future Vision at iFX EXPO Asia 2026
Hong Kong, Hong Kong, August 13th, 2026, FinanceWire
SBCFX has announced its participation in iFX EXPO Asia 2026, one of the leading B2B exhibitions for the online trading, fintech, and financial services sectors.
Scheduled to take place on 8–9 October 2026 at the Hong Kong Convention and Exhibition Centre (HKCEC), the event is expected to attract a diverse range of industry stakeholders, including brokers, traders, investors, Introducing Brokers (IBs), affiliates, fintech companies, liquidity providers, and financial services professionals from across Asia and beyond.
As part of its ongoing international expansion strategy, SBCFX will showcase its integrated trading ecosystem, including the MetaTrader 5 (MT5) platform, multi-asset CFD trading capabilities, institutional-grade liquidity services, and its latest digital trading solutions. The company will also use the exhibition as a platform to share its growth strategy, technology roadmap, and long-term vision for the evolving global trading landscape.
“iFX EXPO Asia represents an important opportunity for SBCFX to strengthen its engagement with the Asian trading community and further expand its regional network,” said David, CEO of SBCFX.
“Our ambition is to become one of the most trusted global trading brands by bridging technology, education, and market access. We believe the future of online trading is not only about faster execution and better tools, but also about creating an ecosystem where traders, partners, and institutions can grow together. iFX EXPO Asia provides the perfect platform for us to share this vision and connect with the industry.”
Driving Innovation While Building a Sustainable Trading Ecosystem
Technology and innovation remain central to SBCFX’s long-term development strategy. The company continues to invest in digital infrastructure, trading technology, and client-focused solutions designed to enhance trading efficiency and improve user experience across global markets.
Alongside its trading services, SBCFX will soon introduce a new mobile trading application that will provide clients with convenient access to account management, market information, trading tools, and platform services through a unified interface. The upcoming launch reflects the company’s ongoing efforts to improve accessibility and streamline the trading experience for users worldwide.
Looking ahead, SBCFX remains focused on developing innovative solutions that support traders at every stage of their journey while strengthening connections between retail investors, institutional partners, and the broader financial ecosystem. By combining advanced technology with a client-centric approach, the company aims to create a smarter, more connected trading environment that adapts to the evolving needs of modern market participants.
During the two-day event, SBCFX representatives will engage with prospective clients, Introducing Brokers, institutional partners, and technology providers to explore strategic collaborations and support the company’s continued growth across Asia.
Meet SBCFX at Booth 37
SBCFX welcomes individual traders, Introducing Brokers, affiliates, fintech firms, liquidity providers, institutional investors, and technology partners to visit Booth 37 and learn more about the company’s products, services, and strategic development plans.
Visitors to the booth will have the opportunity to meet members of the SBCFX team, explore the company’s latest initiatives, and receive a selection of exclusive SBCFX promotional gifts and event merchandise available throughout the exhibition while supplies last.
To facilitate more in-depth discussions and personalised consultations, attendees are encouraged to schedule a one-on-one meeting with the SBCFX team in advance via the following booking link:
https://forms.cloud.microsoft/r/QwRd66ZmQa
Event Details
Event: iFX EXPO Asia 2026
Date: 8–9 October 2026
Time: 10:00 AM – 6:00 PM
Venue: Hong Kong Convention and Exhibition Centre (HKCEC), Hong Kong
Booth: 37
For media enquiries or further information, please contact SBCFX at cs@sbcfx.com.
About SBCFX
SBCFX is a global financial services provider committed to delivering innovative online trading solutions supported by advanced technology, institutional-grade liquidity, and exceptional client service. Through continuous investment in technology, regulatory compliance, and strategic partnerships, SBCFX provides access to a wide range of global financial markets while empowering traders, Introducing Brokers, affiliates, and institutional partners to achieve long-term success.
With a vision to become a trusted global brokerage, SBCFX remains dedicated to transparency, innovation, and sustainable growth, delivering world-class trading solutions to clients around the world.
Contact
Marketing Executive
Kit Cheung
SBCFX
marketing@sbcfx.com
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