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CMS(867.HK/8A8.SG): Ruxolitinib Phosphate Cream (Lumirix®) Achieves Initial Prescriptions in Multiple Regions in China for Patients with Vitiligo

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SHENZHEN, CHINA On 12 March 2026, China Medical System Holdings Limited (“CMS” or the “Group”) is pleased to announce that its subsidiary, Dermavon Holdings Limited (“Dermavon”, an innovative pharmaceutical company specialized in skin health, which is applying for a separate listing on the Main Board of The Stock Exchange of Hong Kong Limited) has its innovative prescription medicine ruxolitinib phosphate cream (Lumirix®) (the “Product”, marketed as Opzelura® in the U.S., Europe and Canada) recorded the initial prescriptions for vitiligo patients across 30 provincial-level regions. The prescriptions cover approximately a thousand influential public and private medical institutions in the field of skin health and disease management, including Huashan Hospital, Fudan University, Shanghai Skin Disease Hospital, Dermatology Hospital of Southern Medical University, Second People’s Hospital of Chengdu, The First Bethune Hospital of Jilin University, The Second Xiangya Hospital of Central South University, United Family Healthcare Group, among others*. Meanwhile, the Product has become concurrently accessible via over 1,300 offline drugstores as well as JD.com e-commerce platform. *Hospital rankings are listed in no particular order.

As the first topical JAK inhibitor approved in China for the treatment of vitiligo, ruxolitinib phosphate cream has officially launched its large-scale clinical application today, marking a breakthrough in China’s vitiligo treatment landscape and ushering in a new era of precision targeted therapy for vitiligo. Supported by safety and efficacy fully demonstrated in clinical studies, the Product is expected to bring new hope for repigmentation to millions of vitiligo patients.

The rapid commercialization progress of ruxolitinib phosphate cream underscores strong product operation capabilities of CMS (including Dermavon), while also reflecting the robust supports from China’s regulatory reforms in accelerating patient access to clinically urgently needed innovative drugs. Benefiting from the integrated healthcare ecosystem of the Hainan Free Trade Port and the “Urgently Needed Imported Drugs for Clinical Use” policy, the Product initiated pilot clinical use in August 2023 at Boao Super Hospital within the Boao Lecheng International Medical Tourism Pilot Zone. Pilot usage subsequently expanded to designated medical institutions across the Guangdong–Hong Kong–Macao Greater Bay Area, Beijing-Tianjin region and other regions. In accordance with the relevant regulations of China’s real-world data application pilot project, as well as supported by the Hainan Provincial Medical Products Administration and the Administration of the Boao Lecheng International Medical Tourism Pilot Zone, the Product has accumulated real-world clinical data in China under pilot application, significantly accelerating its clinical, registration and approval timelines. The Product received its Drug Registration Certificate on January 30, 2026 (approval date: January 27, 2026).

Following its approval, in less than 1.5 months (including the Chinese New Year holiday), the initial prescriptions for ruxolitinib phosphate cream have been issued across multiple regions and hospitals, reflecting the highly efficient collaboration and concerted efforts among CMS teams, regulatory authorities and business partners. With robust support from the cross-departmental coordination mechanism of the Beijing Daxing Airport Economic Zone Joint Administrative Committee, once import conditions were met, the Product completed customs clearance approval, sampling and related customs procedures within 24 hours, and obtained the drug testing report within 7 working days, representing efficient execution and acceleration for the innovative drugs in China. During this process, the Beijing Municipal Medical Products Administration proactively provided end-to-end policy guidance; the government service center has efficiently completed customs clearance filing; the Beijing Institute for Drug Control has conducted methodological pre-testing to accelerate timelines for innovative drug, and continuous worked during the Chinese Spring Festival; and Daxing Airport Customs provided specialized pre-guidance on declaration and swiftly completed customs review and release. Through parallel workflows and coordinated execution, all parties collectively pressed the “fast-forward button” for the Product’s commercialization, helping this urgently needed innovative therapy reach patients faster.

As the Product enters the large-scale clinical application stage, it is expected to further strengthen Dermavon’s comprehensive dermatology solutions and brand value. Building on its leadership in skin health, Dermavon will continue to improve accessibility of ruxolitinib phosphate cream to benefit more vitiligo patients and steadfastly safeguard public skin health through innovation.

About Vitiligo

Vitiligo is a chronic autoimmune disease characterized by depigmentation of the skin, which results from the loss of pigment-producing cells known as melanocytes. The discolored areas usually get bigger with time and the condition could influence skin on any part of the patients’ body. Vitiligo usually affects the appearance of patients, especially on exposed areas such as the face and neck. According to a study that involved over 1,000 diagnosed vitiligo patients, over 45% of patients have facial involvement, and over 20% of patients have neck involvement[1].The obvious presence of white patches may make patients feel that their appearance has been compromised, which in turn materially affects their social life, and is associated with a significantly higher incidence of mental health disorders; accordingly, there is an urgent need for effective treatment options for vitiligo[2].

It is estimated that there are approximately 10.3 million vitiligo patients in China and non-segmental vitiligo patients account for approximately 8.2 million[1]. Existing therapies, such as topical corticosteroids (TCS) and topical calcineurin inhibitors (TCIs), have clinical limitations, with adverse reactions or limited efficacy with long-term use. Ruxolitinib phosphate cream successfully fills the gap in targeted drug treatment for vitiligo and is of great landmark significance.

More Information About Ruxolitinib Phosphate Cream

Ruxolitinib phosphate cream (Opzelura®), a novel cream formulation of the selective JAK1/JAK2 inhibitor ruxolitinib developed by Incyte, is the first and only drug approved for the repigmentation of non-segmental vitiligo by the U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA)[3,4]. In the U.S., the Product is indicated for the topical treatment of nonsegmental vitiligo in adult and pediatric patients aged 12 years and older, and for the short-term and non-continuous chronic treatment of mild to moderate atopic dermatitis (AD) in non-immunocompromised adult and pediatric patients aged 2 years and older whose disease is not well controlled with topical prescription therapies, or when those therapies are not advisable. In Europe, ruxolitinib phosphate cream is approved for the topical treatment of non-segmental vitiligo with facial involvement in adults and adolescents from 12 years of age. In China, besides vitiligo indication, the product’s NDA for the treatment of mild-to-moderate AD in adults and pediatric patients aged 2 years and older is also under regulatory review, which has been included in the Priority Review List and is expected to accelerate the Product’s AD review process for marketing approval.

The Group, through the subsidiary of Dermavon entered into a Collaboration and License Agreement with Incyte for ruxolitinib phosphate cream on 2 December 2022, obtaining an exclusive license to develop, register and commercialize the Product in Mainland China, Hong Kong Special Administrative Region, Macau Special Administrative Region, Taiwan Region and eleven Southeast Asian countries (the “Territory”) and a non-exclusive license to manufacture the Product in the Territory. The subsidiary of Dermavon has sublicensed the relevant rights for the Product outside of Mainland China to the Group (excluding Dermavon and its subsidiary).

Incyte has worldwide rights for the development and commercialization of ruxolitinib phosphate cream (excluding territories in which exclusive rights have already been licensed), marketed in the United States and Europe as Opzelura®. Opzelura® and the Opzelura® logo are registered trademarks of Incyte.

About CMS

CMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet medical needs.

CMS focuses on the global first-in-class (FIC) and best-in-class (BIC) innovative products, and efficiently promotes the clinical research, development and commercialization of innovative products, enabling the continuous transformation of scientific research into clinical practices to benefit patients.

CMS deeply engages in several specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to promote the in-depth development in its advantageous specialty fields, strengthening the competitiveness of the cardiovascular-kidney-metabolic/ gastroenterology/ ophthalmology/ skin health businesses, bringing economies of scale in specialty fields. Among them, the skin health business (Dermavon) has become a leading enterprise in its field, and is proposed to be listed independently on the SEHK. Meanwhile, CMS continuously promotes the operation and development of its integrated R&D, manufacturing and commercialization chain in Southeast Asia and the Middle East, capturing growth opportunities in emerging markets to support the high-quality and sustainable development of the Group.

Reference:

  1. China Insights Consultancy’s industrial report
  2. Wang G, Qiu D, Yang H, Liu W. The prevalence and odds of depression in patients with vitiligo: a meta-analysis[J]. Journal of the European Academy of Dermatology and Venereology, 2018,32(8):1343-1351. DOI:10.1111/jdv.14739.
  3. The U.S. FDA approval information can be found on the Incyte official website, as follows:

https://investor.incyte.com/news-releases/news-release-details/incyte-announces-us-fda-approval-opzeluratm-ruxolitinib-cream

  1. The EMA approval information can be found on the Incyte official website, as follows:

https://investor.incyte.com/news-releases/news-release-details/incyte-announces-european-commission-approval-opzelurar

CMS Disclaimer and Forward-Looking Statements

This press release is not intended to promote any products to you and is not for advertising purposes. This press release does not recommend any drugs, medical devices and/or indications. If you want to know more about the diagnosis and treatment of specific diseases, please follow the opinions or guidance of your doctor or other medical and health professionals. Any treatment-related decisions made by healthcare professionals should be based on the patient’s specific circumstances and in accordance with the drug package insert.

This press release which has been prepared by CMS does not constitute any offer or invitation to purchase or subscribe for any securities, and shall not form the basis for or be relied on in connection with any contract or binding commitment whatsoever. This press release has been prepared by CMS based on information and data which it considers reliable, but CMS makes no representation or warranty, express or implied, whatsoever, and no reliance shall be placed on, the truth, accuracy, completeness, fairness and reasonableness of the contents of this press release. Certain matters discussed in this press release may contain statements regarding the Group’s market opportunity and business prospects that are individually and collectively forward-looking statements. Such forward-looking statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties and assumptions that are difficult to predict. Any forward-looking statements and projections made by third parties included in this press release are not adopted by the Group and the Company is not responsible for such third-party statements and projections.

 

Media Contact

Brand: China Medical System Holdings Ltd.

Contact: CMS Investor Relations

Website: https://web.cms.net.cn/en/home/

 

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Funinexchange Brings Cricket Fans Closer to the Action as IPL 2026 Season Excitement Builds

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Vadodara, Gujarat- As the excitement builds for the upcoming Indian Premier League season, cricket fans across India and around the world are preparing for weeks of high-intensity matches, thrilling finishes, and unforgettable performances.

The IPL has consistently delivered some of the most exciting moments in modern cricket. From explosive batting displays to nail-biting last-over finishes, the tournament creates an atmosphere that keeps fans glued to their screens. In such a high-energy cricket environment, online platforms such as funexchange and funinexchange allow fans to stay even more connected to the game while following match developments in real time.

The Growing Popularity of Cricket Exchange Platforms

In recent years, online cricket exchange platforms have seen a significant rise in popularity, particularly during major tournaments like IPL. Cricket lovers today seek more than just watching matches—they want to analyze team strategies, predict match outcomes, and engage with the sport on a deeper level.

This is where funinexchange stands out. The platform provides cricket enthusiasts with a streamlined and user-friendly interface designed specifically for sports engagement. Whether it’s predicting match outcomes, tracking team performances, or following live odds updates, funexchange creates an environment where fans can experience cricket in a more dynamic way.

Why IPL Season Drives Massive Online Engagement

The IPL is one of the most followed cricket tournaments in the world, bringing together international stars and domestic talents. Each match carries enormous excitement, and fan engagement peaks during the tournament.

Platforms like funinexchange benefit from this surge in cricket enthusiasm because fans are constantly searching for insights, predictions, and interactive experiences. The fast-paced nature of T20 cricket, combined with the unpredictability of the IPL format, creates the perfect environment for platforms that allow users to engage with match outcomes and strategies.

From opening matches to the final showdown, every IPL game brings fresh opportunities for cricket fans to test their understanding of the sport. With features designed for quick navigation and easy participation, funexchange aims to make the experience simple even for new users.

A Platform Designed for Modern Cricket Fans

One of the biggest strengths of funinexchange is its focus on accessibility and real-time engagement. The platform is built for cricket lovers who want quick access to match information, simple account setup, and smooth functionality across devices.

Users can easily create their funexchange ID and begin exploring the platform’s cricket-focused features. With the IPL season attracting massive viewership every year, having a reliable and responsive platform is crucial for fans who want to stay involved throughout the tournament.

The Future of Digital Cricket Engagement

As cricket continues to grow in the digital era, platforms like funinexchange are shaping how fans interact with the sport. The combination of live match excitement, strategic predictions, and interactive experiences ensures that cricket lovers remain deeply connected to every moment of the game.

With the upcoming IPL2026  season set to deliver another round of thrilling matches, funexchange is positioning itself as a platform where cricket fans can amplify their excitement

ngaged with the world’s most entertaining T20 league.

Company Information

Company: funinexchange
Contact Person: Alpa Ramson
Email: funexchange@yopmail.com
Website: https://funinexchange.vip/

Disclaimer: This article is for informational purposes only and does not constitute financial advice. Cryptocurrency, Casino investments carry risk, including total loss of capital. All market analysis and token data are for informational purposes only and do not constitute financial advice. Readers should conduct independent research and consult licensed advisors before investing.

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A.M.A Selections Unveils Expanded 2026 Collection of Luxury Holiday Villas Across the French Riviera

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From Saint-Tropez to Monaco, the luxury villa rental platform introduces its largest ever portfolio of private holiday homes on the Cote dAzur

Portugal, 13th Mar 2026 – A.M.A Selections, the luxury vacation rental company redefining private villa holidays across Europe and the Caribbean, has announced a significant expansion of its French Riviera portfolio for summer 2026. The curated collection now spans five of the most sought-after destinations on the Cote dAzur, giving discerning travellers unprecedented access to handpicked holiday villas in Saint-Tropez, Cannes, Antibes, and Monaco.

The French Riviera has been a magnet for luxury travellers for more than a century, and the region continues to set the standard for Mediterranean glamour. Recognising the growing demand for private, fully serviced accommodation over traditional five-star hotels, A.M.A Selections has invested heavily in sourcing exceptional holiday villas in the South of France that combine architectural character with contemporary comfort across every major destination on the coast.

Holiday Villas Saint-Tropez – Timeless Glamour Meets Private Luxury

The A.M.A Selections collection of holiday villas in Saint-Tropez features a carefully curated portfolio of private estates in and around the legendary Riviera town. Properties range from contemporary seafront retreats in Ramatuelle, within walking distance of the iconic Pampelonne beach, to restored Provençal bastides surrounded by private vineyards and Mediterranean gardens. Each villa is professionally managed and comes with access to A.M.A Selections’ dedicated concierge team, who can arrange everything from private yacht charters and helicopter transfers to Michelin-starred private chef experiences. Saint-Tropez remains the quintessential summer destination for those seeking a blend of celebrity culture, world-class dining, and the relaxed sophistication that defines the Riviera lifestyle.

Holiday Villas Cannes – Where Film Festival Glamour Meets Year-Round Elegance

For travellers drawn to the city synonymous with the world’s most prestigious film festival, A.M.A Selections offers an outstanding range of holiday villas in Cannes. The portfolio includes grand Belle Époque residences perched above La Croisette with panoramic views of the Mediterranean, as well as sleek modern properties in the surrounding hills of Super-Cannes and Mougins. Beyond the red carpet, Cannes offers a thriving cultural scene, Michelin-starred restaurants, and easy access to the charming hilltop village of Grasse, the perfume capital of the world. A.M.A Selections’ local knowledge ensures guests can experience the authentic Cote dAzur beyond the headlines, with personalised restaurant bookings, private tours, and bespoke excursions arranged through the in-house concierge service.

Holiday Villas Antibes – Old-World Charm and Coastal Sophistication

Situated between Cannes and Nice, the walled town of Antibes and the exclusive peninsula of Cap d’Antibes have attracted royalty, artists, and industrialists for generations. A.M.A Selections’ collection of holiday villas in Antibes encompasses properties ranging from intimate maisons de maître within the old town walls to sprawling waterfront estates on the Cap, many with private beach access and mature landscaped gardens. Antibes combines the authentic Provençal atmosphere of its daily market and medieval ramparts with the exclusive allure of Cap d’Antibes, home to the legendary Hotel du Cap-Eden-Roc. The town’s proximity to the Picasso Museum, Port Vauban – Europe’s largest marina – and the Juan-les-Pins jazz quarter makes it an exceptionally well-rounded destination for luxury villa guests.

Holiday Villas Monaco – The Pinnacle of Riviera Prestige

Completing the French Riviera collection, A.M.A Selections presents an exclusive selection of holiday villas in Monaco and the surrounding communes of Roquebrune-Cap-Martin and Beausoleil. Monaco represents the apex of Riviera luxury, and the properties in this collection reflect that standing – expect private terraces overlooking the Monte Carlo harbour, state-of-the-art wellness facilities, and proximity to the principality’s legendary casino, Grand Prix circuit, and haute couture boutiques. For guests seeking the ultimate in privacy and prestige, A.M.A Selections’ Monaco portfolio delivers an experience that rivals the finest hotels in the world, with the added freedom and exclusivity of a private residence.

The A.M.A Selections Difference

Every property listed on the A.M.A Selections platform is personally vetted to meet rigorous standards of quality, design, and service. Unlike mass-market booking platforms, A.M.A Selections operates a high-touch model in which each guest is assigned a dedicated concierge from the moment of booking through to departure. Services include pre-arrival planning, private chef arrangements, restaurant reservations, yacht and helicopter charters, spa treatments, and curated excursions – all tailored to the guest’s preferences.

The company’s proprietary platform and mobile app allow guests to browse properties, communicate with their concierge, manage itineraries, and share trip details with travel companions, combining the warmth of personal service with the convenience of modern technology.

“The French Riviera is where A.M.A Selections began, and it remains at the heart of everything we do. Our 2026 collection represents our deepest commitment yet to this extraordinary coastline – we’ve handpicked properties across Saint-Tropez, Cannes, Antibes, and Monaco that embody the very best of Riviera living. Our guests expect perfection, and we’re proud to deliver it.” – A.M.A Selections

About A.M.A Selections:

A.M.A Selections is a luxury vacation rental company offering a curated portfolio of private villas and chalets across more than 100 destinations in Europe, the Caribbean, and the United States. The company combines a rigorously vetted property collection with a dedicated concierge service and proprietary booking platform. A.M.A Selections operates across the French Riviera, Provence, Tuscany, Amalfi Coast, Puglia, Sardinia, Ibiza, Mallorca, Costa del Sol, Mykonos, the French Alps, St. Barts, Turks and Caicos, and California, among other destinations.

Media Contact

Organization: A.M.A Selections

Contact Person: A.M.A Selections

Website: https://amaselections.com/

Email: Send Email

Country:Portugal

Release id:42598

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A.M.A Selections Unveils Expanded 2026 Collection of Luxury Holiday Villas Across Greece

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From the Cyclades to the Ionian Islands and Crete, the luxury villa rental platform introduces its most comprehensive Greek portfolio to date.

Portugal, 13th Mar 2026 – A.M.A Selections, the luxury vacation rental company redefining private villa holidays across Europe and the Caribbean, has announced a significant expansion of its Greek portfolio for summer 2026. The curated collection now features handpicked properties across five of the country’s most sought-after island destinations, offering discerning travellers unprecedented access to holiday villas in Corfu, Mykonos, Paros, Santorini, and Crete.

Greece has long captivated luxury travellers with its extraordinary combination of ancient history, crystalline Aegean waters, and a culinary tradition that ranks among the finest in the Mediterranean. Recognising the growing demand for private, fully serviced accommodation across the Greek islands, A.M.A Selections has invested heavily in sourcing exceptional holiday villas in Greece that combine authentic Cycladic and Ionian architecture with contemporary luxury.

Holiday Villas Corfu – Lush Ionian Beauty and Venetian Grandeur

The A.M.A Selections collection of holiday villas in Corfu showcases the Ionian island’s distinctive character – a lush, green landscape quite unlike anything found in the Cyclades. Properties range from grand Venetian-influenced estates with sweeping coastal views to contemporary waterfront retreats with private beach access, heated infinity pools, and spa facilities. Corfu’s Old Town, a UNESCO World Heritage Site, offers a rich blend of Byzantine, Venetian, French, and British architecture, while the island’s rugged northern coastline and tranquil southern beaches provide an extraordinary diversity of scenery within a single destination.

Holiday Villas Mykonos – The Queen of the Greek Islands

For travellers drawn to the most glamorous island in the Aegean, A.M.A Selections offers an outstanding range of holiday villas in Mykonos. The portfolio includes contemporary clifftop estates with panoramic views of the Aegean, whitewashed retreats within walking distance of Mykonos Town’s iconic windmills, and exclusive beachfront properties near Psarou, Ornos, and Ftelia. Although famous for its vibrant nightlife and world-renowned beach clubs, Mykonos offers far more than the party scene – hidden coves with crystal-clear waters, award-winning restaurants, and a thriving art gallery scene that continues to attract a discerning international crowd.

Holiday Villas Paros – The Authentic Heart of the Cyclades

Paros has rapidly emerged as one of the most desirable islands in the Aegean, and the A.M.A Selections collection of holiday villas in Paros reflects the island’s irresistible blend of traditional charm and understated sophistication. Properties range from contemporary beachfront estates near the fashionable port town of Naousa to secluded waterfront retreats overlooking Golden Beach on the island’s eastern coast. The slow-paced way of life is the real luxury of Paros – whitewashed villages draped in bougainvillea, family-run tavernas serving the freshest grilled fish, and unspoilt coves with emerald-coloured water that feel a world away from the busier neighbouring islands.

Holiday Villas Santorini – Volcanic Drama and World-Famous Sunsets

No Greek island portfolio would be complete without Santorini, and A.M.A Selections’ collection of holiday villas in Santorini captures the volcanic island at its most spectacular. Properties perch along the caldera rim in Oia and Fira, offering uninterrupted views of the legendary sunset over the submerged crater, while others are set among the island’s renowned vineyards and dramatic red and black sand beaches. Santorini’s unique terroir has produced an increasingly celebrated wine scene, and the island’s ancient archaeological sites – including the remarkably preserved Minoan settlement of Akrotiri – add a layer of cultural depth that sets it apart from any other Mediterranean destination.

Holiday Villas Crete – Where Mythology Meets the Mediterranean

Completing the Greek collection, A.M.A Selections presents an exceptional selection of holiday villas in Crete, the largest and most diverse of all the Greek islands. Properties span the island’s dramatic northern coastline, from contemporary eco-chic retreats near Heraklion with infinity pools and direct sea access to restored stone farmhouses in the olive groves of the western interior. Crete’s extraordinary depth of history – from the Minoan palace of Knossos to Venetian harbour towns such as Chania and Rethymno – is matched by a vibrant food scene rooted in one of the world’s oldest culinary traditions.

The A.M.A Selections Difference

Every property listed on the A.M.A Selections platform is personally vetted to meet rigorous standards of quality, design, and service. Each guest is assigned a dedicated concierge from booking through to departure, with services including private chef arrangements, restaurant reservations, yacht charters, spa treatments, and curated excursions – all tailored to individual preferences.

Greece occupies a truly special place in our portfolio – from the cosmopolitan energy of Mykonos to the timeless tranquillity of Paros and the dramatic beauty of Santorini, these islands offer an extraordinary range of experiences. Our 2026 collection is our most ambitious Greek offering yet, and we’re proud to share it with travellers who demand the very best.” – Co-Founder, A.M.A Selections

Media Contact

Organization: A.M.A Selections

Contact Person: A.M.A Selections

Website: https://amaselections.com/

Email: Send Email

Country:Portugal

Release id:42602

The post A.M.A Selections Unveils Expanded 2026 Collection of Luxury Holiday Villas Across Greece appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section

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