Press Release
New Clinical Data Reveals MAIA Biotechnology’s THIO Achieves High Efficacy In Advanced Non-Small Cell Lung Cancer Treatment
–News Direct–
By Mangeet Kaur Bouns
Lung cancer remains the top cause of cancer-related deaths in the U.S., accounting for approximately 20% of all cancer fatalities. The American Cancer Society's projections for 2024 highlight the gravity of this issue, with an estimated 234,580 new lung cancer cases and about 125,070 deaths anticipated in the U.S. Of these, nearly 80% to 85% are non-small cell lung cancer (NSCLC) cases, highlighting the urgent need for effective treatments.
MAIA Biotechnology, Inc. (AMEX: MAIA), a clinical-stage biopharmaceutical company focused on developing telomere-targeting immunotherapies for cancer treatment, has unveiled promising new clinical data showcasing the efficacy of its lead product candidate, THIO, in treating NSCLC. This data emerges from a phase 2 clinical trial evaluating THIO in combination with the immune checkpoint inhibitor (CPI) cemiplimab (Libtayo), targeting patients with advanced NSCLC who have not responded to at least two standard-of-care therapies.
In the context of NSCLC, where traditional treatments often fall short, THIO's potential as a first-in-class telomere-targeting agent raises hope. Its ability to disrupt cancer cell telomeres and stimulate immune responses marks a significant advancement in the fight against this devastating disease.
MAIAs Lead Candidate: THIO
THIO is a groundbreaking telomere-targeting agent, currently undergoing phase 2 clinical trials aimed at treating NSCLC with telomerase-positive cancer cells. Telomerase, present in over 85% of human cancers, plays a crucial role in the immortality and proliferation of cancer cells. THIO integrates into telomeres within these cells, disrupting their structure and function leading to rapid tumor cell death.
By inducing telomerase-dependent DNA modification and damage, THIO triggers selective cancer cell death. This process accumulates telomeric damage in cytosolic micronuclei, which then activates both innate (cGAS/STING) and adaptive (T-cell) immune responses. In in vivo cancer models, sequential treatment with THIO followed by PD-(L)1 inhibitors resulted in significant and sustained tumor regression, fostering cancer-specific immune memory.
Key Findings From The Phase 2 THIO-101 Clinical Trial
The phase 2 THIO-101 trial primarily focuses on assessing the safety and tolerability of THIO both as an anticancer agent and as an immune system activator, alongside evaluating its clinical efficacy through overall response rate (ORR).
The trial results are noteworthy. The disease control rate (DCR) for THIO in combination with CPI was 85%, far exceeding the 25-35% DCR typically seen with chemotherapy in third-line treatments. Additionally, 65% of patients surpassed the 5.8-month overall survival (OS) threshold, and 85% exceeded the 2.5-month progression-free survival (PFS) threshold, demonstrating significant clinical benefits. The median survival follow-up time stood at 9.1 months for the cohort of 20 patients.
Optimal dose selection yielded even more impressive outcomes. Patients in third-line receiving 180mg of THIO exhibited a median PFS of 5.5 months, a 75% OS rate at six months and an ORR of 38%, compared to the standard 6-10% ORR for chemotherapy. Notably, 75% of these patients crossed the 5.8-month OS threshold and 88% surpassed the 2.5-month PFS threshold, with a median survival follow-up time of 9.1 months among the eight patients assessed.
Implications And Future Directions
Dr. Vlad Vitoc, chairman and CEO of MAIA, expressed enthusiasm about the trial outcomes, noting, "All exceptional measures of efficacy in our trial to date have exceeded our own expectations and outperformed standard-of-care treatments." He emphasized THIOs potential as a robust, safe and highly effective alternative for patients who have not benefited from chemotherapy and other treatments.
The THIO-101 trial, which completed enrollment ahead of schedule in February, reached its target of 41 patients for the 180 mg dose. This data, which indicates promising disease control and overall response rates, paves the way for further investigation and potential redefinition of cancer treatment protocols.
As THIO-101 data continues to demonstrate favorable disease control and response rates, with full efficacy data anticipated in the latter half of this year, MAIA Biotechnology stands poised to redefine cancer treatment. THIOs promise to transform the standard of care in oncology offers new hope to patients with advanced NSCLC, potentially establishing a new benchmark in cancer therapy.
Featured photo by CI Photos at Shutterstock.
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Press Release
Taps Pest Control Expands Comprehensive Pest Management Services Across Tampa and Surrounding Areas
Taps Pest Control now delivers full-scale pest control solutions tailored for homes and businesses throughout Tampa, FL, and the surrounding metro area—providing effective treatments for urban and suburban infestations.
Tampa, FL – May 2025 — Taps Pest Control, a trusted leader in pest management, has expanded its comprehensive pest control services across Tampa and the surrounding regions. Known for its reliable and results-driven approach, the company offers year-round protection for both residential and commercial properties.
With Florida’s largest metropolitan area facing a wide range of pest challenges, Taps Pest Control provides expert solutions tailored to local environmental conditions. From ants, roaches, and spiders to rodents and termites, the company uses advanced, eco-conscious treatment methods to ensure long-term results.
Serving both densely populated urban neighborhoods and rapidly growing suburban communities, Taps Pest Control customizes its services to fit the unique pest pressures of each location. The company’s licensed professionals use integrated pest management strategies that are effective, safe, and environmentally responsible.
Taps Pest Control continues to make client satisfaction its top priority, offering flexible scheduling, routine maintenance plans, and prompt customer support throughout the Tampa Bay area.
Media Contact
Organization: Taps Pest Services
Contact Person: Alexander Dauberman
Website: https://tapspestservices.com/
Email: Send Email
Contact Number: +18135927643
Address:9623 Mathog Rd, Riverview, FL 33578
City: Riverview
State: Florida
Country:United States
Release id:28226
The post Taps Pest Control Expands Comprehensive Pest Management Services Across Tampa and Surrounding Areas appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section
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Press Release
Global Forex Breakthrough ACM Launches the C-ModuleUshering in a New Era for the Forex Industry
Global Forex Breakthrough: ACM Launches the “C-Module”Ushering in a New Era for the Forex Industry
Core Summary
A Capital Management (ACM) has officially launched its ground-breaking innovation — the “C-Module”, a disruptive concept that merges Self Trading with intelligent asset management. This new model opens a high-efficiency, low-risk path to wealth growth for global forex investors. More than just a product innovation, the C-Module represents a rethinking of trading logic — empowering funds with a “dual engine”, the stability of professional Follow Trade and the unlimited potential of Self Trading strategy.
Core Highlights — How the C-Module Is Disrupting Traditional Forex Trading
Q1: What inspired the creation of the C-Module?
ACM Team:
The concept was born from a long-standing challenge in the industry. Many clients have a strong interest in forex trading and possess solid trading skills but hesitate to go fully solo. They’re reluctant to hand over all capital to asset managers, yet don’t want to trade entirely alone. On the other hand, professional traders often face the dilemma of managing clients, providing education, and overseeing risk — leaving little time to focus purely on trading.
We asked ourselves: Could a single fund serve both needs? In the C-Module, clients are allocated two equal-value accounts: one is managed by us — the Follow Trade Account, and the other is a Self Trading Account operated independently by the client or their appointed trader. That’s how the initial vision of the C Module took shape.
Q2: How does the C-Module function at its core?
ACM Team:
The core mechanism is: “One capital, dual engines.” Investors allocate funds to a Follow Trade Account, managed by ACM to generate stable returns. At the same time, the broker
provides an equivalent value Self Trading Account for the investor’s own strategy. Profits from the Self Trading Account belong entirely to the trader. Even in the event of trading losses, investors continue to benefit from the Follow Trade Account’s returns. This structure allows clients to manage trading accounts with greater flexibility while maintaining full control over their risk exposure — leading to more efficient capital management.
Q3: What key advantages does the C-Module offer?
ACM Team:
The C-Module breaks away from the traditional conflict-driven structure in forex trading. In the past, traders, platforms, and brokers often found themselves in opposition due to misaligned interests. The C-Module, however, brings everyone onto the same page through shared incentives, creating a true “win-win-win” structure: the more active the trader, the higher the volume, the more stable the returns for the broker and platform. Behind this mechanism is a more transparent, cooperative, and sustainable logic that promotes long-term growth across the entire ecosystem.
Q4: Is the C-Module just a product, or a broader industry strategy?
ACM Team:
The C-Module is much more than a standalone financial product. It’s a complete and structured system. It redefines how asset managers and traders collaborate, paving the way toward greater specialization and sustainable development within the forex industry. We’re building a full ecosystem around it: including infrastructure, risk controls, and trader education. For instance, our strategic partner, SHA Academy, provides practical training and long-term career support for aspiring traders. Whether you’re just starting out or already a seasoned professional, the C Book offers a flexible and scalable platform for growth.
Q5: How do you view the future of the C-Module in the forex industry?
ACM Team:
While the forex market is inherently volatile, models built on clear logic and fair value sharing will always endure. The C-Module is not a passing trend, it represents a fundamental shift in how the industry operates.
It helps fix common problems in traditional trading: unclear profit logic, inconsistent results, and constant friction between brokers and traders. What truly makes the C-Module stand out is that it bridges two kinds of investors. Those who want to take the reins with Self Trading, and those who prefer steady, professional returns through Follow Trade. Instead of forcing a choice, it lets users enjoy the best of both worlds — with clarity, control, and long-term potential.
Conclusion
In a global forex market full of new momentum and smarter strategies, the C-Module opens a clearer, more dynamic path forward. It not only boosts capital efficiency, but also marks a strategic upgrade to the industry’s operational model — laying the groundwork for a more professional, transparent, and collaborative forex ecosystem.
Media Contact: Email: support@acapman.com Website: https://www.acapman.com
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Organization: A Capital Management
Contact Person: Coco
Website: https://www.acapman.com/
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The post Global Forex Breakthrough ACM Launches the C-ModuleUshering in a New Era for the Forex Industry appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section
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Press Release
COOFANDY Launches 10th Anniversary Celebration: Unveils Dual Slogans to Interpret New Brand Proposition, Embarking on a Dual Journey of Fashion and Life
After a decade of meticulous cultivation, COOFANDY has witnessed the magnificent transformation of men’s wardrobes. With the dual unveiling of slogans, it defines the profound connection between fashion and life. Recently, COOFANDY, a globally renowned men’s fashion brand, officially announced the launch of its 10th-anniversary celebration series of activities, simultaneously revealing its new brand slogan “Dress the Journey” and the 10th-anniversary campaign slogan “Dress the Win”. With the innovative concept of “Clothing as the Narrative of Life”, it once again reshapes the industry’s perception of the value of men’s fashion brands.
A Decade of Journey: From Upholding Original Aspirations to Becoming an Industry Benchmark, Reshaping Men’s Sartorial Philosophy
Since its establishment in 2015, COOFANDY has always adhered to its mission of “enabling every man to look his best at every stage of life”. It has built a comprehensive product line covering business shirts, suits, casual wear, and formal attire. Sidney Sun, the Chief Marketing Officer of COOFANDY, reflected on the decade-long journey, stating, “We have never regarded clothing as mere external decoration but as a ‘witness’ and ‘participant’ in significant moments of life. Whether it’s a suit for a job interview when entering the workforce, a celebratory outfit for a promotion, or casual wear after becoming a father, COOFANDY has always accompanied users in writing their own life chapters with exquisite designs and high-quality fabrics.”
With its unwavering pursuit of quality and keen insight into consumer needs, COOFANDY has earned widespread trust from global consumers as a “versatile wardrobe companion”. Its products prioritize ergonomic tailoring and utilize functional fabrics with breathability and wrinkle resistance, allowing wearers to maintain an elegant demeanor in business meetings, social events, and even casual activities.
Dual Slogan Strategy: Defining the Profound Connection Between Fashion and Life
The dual slogans released this time constitute a dual dimension of brand value:
Brand Slogan: ‘Dress the Journey’Focusing on the positioning of being a “companion on life’s journey”, it emphasizes that clothing is a witness to life’s stages. Sidney Sun further elaborated, “‘Journey’ not only refers to the physical trajectory of growth but also represents self-realization on a spiritual level. We hope to break the stereotype of ‘men’s fashion = single business style’ and enable men to maintain confidence in different role transitions through diverse designs—whether it’s a solemn occasion in the boardroom or a weekend family gathering, COOFANDY can provide suitable attire solutions.”
10th-Anniversary Campaign Slogan: ‘Dress the Win’Centered around the “ritualistic sense of victory moments”, it advocates honoring every achievement with attire. The brand believes that every victory deserves a perfect outfit to match. COOFANDY, with its philosophy of “dressing to celebrate victory”, captures moments of glory while encouraging men to confidently express their individuality and charm through clothing, allowing their unique allure to shine naturally in significant life scenarios.
In addition to upgrading its brand philosophy, COOFANDY has also injected cross-border elements into its 10th-anniversary celebration. It is revealed that the brand will form a strategic partnership with a certain top-tier racing team and launch a global brand ambassador program, echoing the core theme of “Dress the Win” with the “speed, passion, and precision” spirit of auto racing.
Future Outlook: From “Wardrobe Supplier” to “Lifestyle Partner”
The 10th anniversary is not an endpoint but a new starting point. COOFANDY firmly believes that the ultimate value of clothing lies not in the ebb and flow of trends but in accompanying users through every significant milestone of life, helping them become the “best version of themselves”. Whether in the workplace, family, or recreational pursuits, COOFANDY will continue to empower modern men’s diverse lifestyle scenarios with high-quality products and innovative concepts.
With the unveiling of the dual slogans and the preheating of a series of activities, COOFANDY is redefining the emotional value of men’s fashion brands with its new image as a “companion on life’s journey”. In the current era of consumption upgrading and the awakening of men’s fashion consciousness, can this decade-old brand carve out a new niche in the competitive men’s fashion market with its innovative concept of “clothing as the narrative of life”? Perhaps, as its slogans suggest—when fashion transcends mere appearance and becomes an extension of inner spirit, the next decade of COOFANDY is already worth anticipating.
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Global Forex Breakthrough ACM Launches the C-ModuleUshering in a New Era for the Forex Industry
Taps Pest Control Expands Comprehensive Pest Management Services Across Tampa and Surrounding Areas
COOFANDY Launches 10th Anniversary Celebration: Unveils Dual Slogans to Interpret New Brand Proposition, Embarking on a Dual Journey of Fashion and Life
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