Press Release

Unlock Protein Regulation with MtoZ Biolabs Quantitative Ubiquitinomics Service

Published

6 hours ago

July 15, 2025

Quantitative ubiquitinomics service provides a specialized solution for the precise identification, quantification, and characterization of ubiquitinated proteins within complex biological samples. MtoZ Biolabs integrates mass spectrometry-based ubiquitinomics solutions with advanced technologies, utilizing Orbitrap Fusion Lumos, Q Exactive HF, and Orbitrap Exploris systems. These state-of-the-art platforms, combined with Nano-LC systems and optimized fragmentation techniques (HCD, ETD), enable high-resolution detection of ubiquitin-modified peptides, even at low abundances.

Ubiquitination, characterized by the attachment of ubiquitin to lysine residues on target proteins, is marked by a characteristic K-ε-GG motif and a mass shift of approximately 114.1 Da. This unique modification is detectable through high-resolution mass spectrometry, allowing for precise identification and quantification of ubiquitinated peptides. Our quantitative ubiquitinomics service delivers high-throughput analysis, providing detailed ubiquitination profiles, including site localization and dynamic quantification of ubiquitination events under physiological and pathological conditions. Through the integration of sophisticated bioinformatics, we offer researchers comprehensive and actionable data, enabling insights into ubiquitin-mediated protein regulation that are crucial for understanding disease mechanisms, protein homeostasis, and signaling networks.

Understanding Ubiquitination: The Ubiquitin Code and Its Biological Significance

Ubiquitination is a post-translational modification in which the ubiquitin protein, a 76-amino-acid polypeptide, is covalently attached to lysine residues on target proteins, forming an isopeptide bond. This modification plays a critical role in regulating protein stability, localization, and function. Ubiquitination can occur as mono- or poly-ubiquitin chains, with different types of linkages serving distinct functions. For instance, K48-linked chains typically signal proteasomal degradation, while K63-linked chains are involved in signal transduction.

The ubiquitin code is fundamental to a variety of essential cellular processes, such as DNA repair, endocytosis, immune response, and metabolic regulation. These processes are orchestrated through a network of ubiquitination events that control cellular responses to internal and external signals. The development of mass spectrometry-based ubiquitinomics solutions has greatly enhanced our ability to map and quantify these modifications, providing deeper insights into their role in cellular functions and disease pathogenesis

Applications of Quantitative Ubiquitinomics

Oncology: Precision Mapping of Tumor Ubiquitin Landscapes

Quantitative ubiquitinomics plays a crucial role in understanding how ubiquitination regulates cancer progression. Studies have shown that E3 ubiquitin ligases and deubiquitinases regulate the stability of oncogenic proteins like Myc, p53, and β-catenin, which drive tumorigenesis. High-throughput ubiquitinomics has enabled the discovery of tumor-specific ubiquitin modifications and their dynamic changes in response to chemotherapeutic agents. For example, the ubiquitinome of triple-negative breast cancer cells has been mapped, identifying upregulated K63-linked ubiquitination on key signaling proteins, providing potential targets for therapeutic intervention. The integration of quantitative ubiquitinomics and phosphoproteomics can assist in stratifying patients for targeted treatments and predicting therapy resistance.

Neurodegenerative Diseases: Profiling Pathological Ubiquitination

Neurodegenerative disorders, such as Alzheimer’s and Parkinson’s diseases, are characterized by the accumulation of misfolded and aggregated proteins. Quantitative ubiquitinomics enables the precise mapping of ubiquitin modifications associated with these aggregates. Recent studies on Alzheimer’s models have shown specific ubiquitination of tau and amyloid precursor protein (APP), shedding light on the mechanisms of aggregate formation. Moreover, integrating ubiquitinomics with single-cell proteomics allows for the discovery of cell-type-specific ubiquitination patterns, offering deeper insights into selective neuronal vulnerability.

Immunology: Decoding Ubiquitin-Dependent Immune Signaling

Ubiquitination is critical for regulating immune signaling pathways, including NF-κB, type I interferon responses, and T-cell receptor signaling. Quantitative ubiquitinomics has been used to chart dynamic ubiquitin landscapes in immune cells activated by pathogens or cytokines. Studies have identified novel E3 ligases and DUBs (deubiquitinases) as key regulators of immune checkpoints. Additionally, therapeutic modulation of ubiquitin pathways, such as targeting the E3 ligase cIAP1/2, shows promise in enhancing antitumor immunity and overcoming immune evasion by cancers.

Plant and Microbial Systems: Ubiquitinomics in Non-Animal Contexts

In plant biology, ubiquitinomics has advanced our understanding of stress adaptation, hormone signaling, and developmental processes. For instance, in rice and Arabidopsis, the ubiquitin-modified protein mapping under drought and salt stress has highlighted key regulators such as transcription factors and metabolic enzymes. In microbial systems, recent research has uncovered prokaryotic ubiquitin-like proteins (PUPs), which target the proteasome in mycobacteria, offering new antimicrobial targets. The integration of ubiquitinomics with CRISPR-based gene editing offers promising applications in crop improvement and synthetic biology.

Drug Discovery and Precision Medicine: Informing Therapeutic Strategies

Quantitative ubiquitinomics provides critical insights into drug-induced changes in ubiquitination profiles, helping identify compound specificity and potential off-target effects. For example, in PROTACs (proteolysis-targeting chimeras) development, ubiquitinomics is used to confirm target degradation and identify secondary ubiquitination events. Precision medicine efforts are leveraging patient-derived samples (e.g., xenografts, organoids) for personalized ubiquitin landscape mapping, aiding in targeted therapy selection and predicting therapeutic responses.

Systems Biology and Future Perspectives

Integrating quantitative ubiquitinomics with multi-omics approaches (e.g., phosphoproteomics, transcriptomics, metabolomics) enables the construction of comprehensive cellular signaling models. These models reveal the interplay between ubiquitination and other regulatory mechanisms, providing a holistic understanding of complex biological processes. Future directions include applying real-time ubiquitinomics with novel technologies like trapped ion mobility spectrometry (TIMS) and data-independent acquisition (DIA) to capture dynamic ubiquitination events in live cells.

Additionally, machine learning algorithms are being developed to predict ubiquitin-mediated network behaviors.

Advantages of MtoZ Biolabs’ Quantitative Ubiquitinomics Service

MtoZ Biolabs offers a comprehensive, high-precision quantitative ubiquitinomics service that integrates cutting-edge mass spectrometry with targeted peptide enrichment to deliver reliable and reproducible data. Key advantages include:

Advanced Analysis Platform

We utilize Orbitrap Fusion Lumos, Q Exactive HF, and Orbitrap Exploris systems, coupled with Nano-LC for high-resolution separation and accurate mass measurements, ensuring superior data quality across various sample types.

Targeted Peptide Enrichment

Our service includes the use of anti-K-ε-GG antibodies to selectively enrich ubiquitinated peptides, enhancing detection sensitivity and enabling accurate quantification, even for low-abundance proteins.

Versatility Across Sample Types

MtoZ Biolabs’ service is optimized for a wide range of sample types, including cells, tissues, biofluids, plants, and microbial cultures, ensuring scalability and consistency in high-throughput projects.

Standardized Protocols

Rigorous sample preparation, digestion protocols (trypsin, Lys-C, Glu-C), and optimized peptide enrichment ensure high data fidelity, making our service reliable for diverse experimental needs.

Sample Submission Suggestions of MtoZ Biolabs’ Quantitative Ubiquitinomics Service

To ensure optimal results from our quantitative ubiquitinomics service, please adhere to the following sample submission requirements:

Serum/Plasma

≥100 μL, stored at -80°C, minimal freeze-thaw cycles.

Urine

≥2 mL, sterile handling, stored at -80°C.

Tissues

≥200 mg (animal) or 10 g (plant), snap-frozen in liquid nitrogen.

Cells

≥1×10^8 cells, PBS-washed, frozen.

Microbial Cultures

≥500 μL, labeled, contamination-free.

Protein Extracts

≥5 mg, quantified, buffer-compatible, free of interfering components.

Customized preprocessing is available for low-abundance or challenging samples.

Why Choose MtoZ Biolabs’ Quantitative Ubiquitinomics Service?

Partnering with MtoZ Biolabs for your quantitative ubiquitinomics service ensures access to a uniquely balanced combination of technological sophistication, scientific rigor, and client-oriented service. Here’s why we stand out:

Comprehensive Technological Support

Our mass spectrometry solutions leverage top-tier instrumentation, including Orbitrap Fusion Lumos and Q Exactive HF, with automated workflows that ensure high sensitivity and reproducibility.

Expert Bioinformatics

Our bioinformatics platform integrates curated databases (e.g., PhosphoSitePlus, Unimod) with custom algorithms to generate detailed ubiquitination profiles, including site localization and quantification, with expert interpretation tailored to your needs.

Customizable Workflows

We offer tailored workflows to accommodate different sample types and research objectives, from clinical samples to rare specimens, ensuring precision and scalability in every project.

Transparent and Client-Friendly Pricing

We offer a one-time, transparent pricing model that includes all aspects of the service, from sample preparation and enrichment to mass spectrometry analysis and bioinformatics reporting. Clients can confidently plan projects without concerns about hidden fees or incremental costs.

What Could Be Included in Your Quantitative Ubiquitinomics Service Report?

Upon project completion, clients receive a detailed, customized report containing:

Comprehensive Experimental Details

A thorough description of all experimental procedures, including sample collection and handling, buffer compositions, digestion protocols, and specific enrichment techniques tailored to ubiquitinated peptide capture.

Materials, Instruments, and Methods

A complete list of materials used, including reagents, consumables, antibodies, as well as detailed instrument configurations such as mass spectrometer settings (e.g., resolution, AGC target, maximum injection time) and Nano-LC gradient conditions.

Total Ion Chromatogram & Quality Control Assessment (Project-Dependent)

Visual representations of chromatographic profiles and internal standards for quality control, including signal stability and retention time reproducibility for both enriched and unenriched fractions.

Data Analysis, Preprocessing, and Estimation (Project-Dependent)

A breakdown of data preprocessing workflows including noise filtering, baseline correction, charge state determination, and false discovery rate (FDR) thresholds. Estimation of peptide abundances and dynamic range across experimental replicates.

Comprehensive Bioinformatics Analysis
Ubiquitination Site Mapping: High-confidence localization of ubiquitination sites with site probability scores, cross-referenced against known databases (e.g., PhosphoSitePlus).
Functional Annotation: Gene ontology (GO) and KEGG pathway analysis highlighting biological processes and molecular functions affected by ubiquitination.
Protein Interaction Networks: Visualization of protein-protein interactions and signaling pathways influenced by ubiquitin modifications, including subnetworks of disease
Custom Visualizations: Graphical representations such as volcano plots, heatmaps, and site occupancy maps, providing intuitive insights into the data.

Raw Data Files

Complete raw data generated by mass spectrometry runs, provided in vendor-compatible formats (e.g., Thermo RAW) for downstream reanalysis. Processed data files (e.g., mzML, mzIdentML) with metadata annotations are also included.

MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, provides advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption.

As research into protein post-translational modifications continues to advance, quantitative ubiquitinomics has emerged as a core technique for unraveling the mechanisms of protein homeostasis regulation. By combining advanced mass spectrometry platforms, highly specific enrichment strategies, and systematic data analysis methods, MtoZ Biolabs offers high-quality, reliable mass spectrometry-based ubiquitinomics solutions to researchers worldwide. Our vision is to bring new vitality to life science research through continuous innovation in this field, helping to reveal molecular mechanisms, identify disease targets, and accelerate new drug development.

If you would like to learn more about how our quantitative ubiquitinomics service can advance your research outcomes, please contact us for a free one-on-one technical consultation.

Media Contact

Organization: MtoZ Biolabs

Contact Person: Terry

Website: https://www.mtoz-biolabs.com

Email: Send Email

Contact Number: +18573629535

Address:155 Federal Street, Suite 700

City: Boston

State: MA

Country:United States

Release id:30660

The post Unlock Protein Regulation with MtoZ Biolabs Quantitative Ubiquitinomics Service appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section

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Press Release

BLDR is the Premier Choice for Custom Home Building in Austin Ensuring Unmatched Luxury

Published

47 minutes ago

July 15, 2025

Cloud PR Wire

BLDR Is the topmost choice when it comes to building custom homes with matchless luxury in Austin, providing customers with stunning properties for refined living and promising ultimate satisfaction at every moment.

Austin, TX (July 15, 2025) – Everyone has a vision of a dream home, a residence that stands out for its uniqueness, matching personal needs and lifestyle with the assurance of living life king or queen-size. BLDR is making such dreams come true easily. Led by esteemed builder Bryan Murphy, it is redefining the art of custom home building Austin that residents can rely on.

BLDR is the Premier Choice for Custom Home Building in Austin Ensuring Unmatched Luxury

BLDR Is the topmost name when it comes to creating luxury homes that stand out for flawless craftsmanship and distinctive architectural design. The team of the company has managed to transform some of the most prestigious neighborhoods of Austin, from Westlake to Pemberton, with stunning projects. Clients are enjoying supreme satisfaction with gorgeous properties that capture the essence of refined living.

As a custom home building contractor Austin TX that residents trust, Bryan works with a comprehensive process that begins with understanding client’s dreams, followed by action. Bryan works directly with clients from the initial meeting, guiding them through site assessment, design collaboration, and the creation of detailed construction plans that perfectly translate their ideas into reality.

At BLDR, the construction process is meticulous and absolutely satisfying. It starts with the foundation and framing of the home, followed by the installation of advanced mechanical, electrical, and plumbing systems. Next, interior details such as wallboard and trim bring the aesthetic vision to life before final landscaping and finishing touches complete the masterpiece. At every step, only high-end materials sourced from reputable suppliers are used.

“With each project we’re trying to raise the bar when it comes to luxury home creations,” says a spokesperson for BLDR, “And with Murphy, we are trying to make client’s visions transform into the most stunning realities ever seen.”

Unlike many other Austin custom home builders, BLDR prioritizes client relationships by offering direct communication with Bryan Murphy throughout the project. Due to this personalized approach, the whole process is streamlined and every detail aligns with the client’s expectations.

Beyond custom home building, BLDR also excels in renovations, home additions, kitchen and bathroom remodeling, and historic home restorations. Whether it comes to creating a serene outdoor oasis, redesigning interiors with contemporary elegance, or preserving the charm of a historic property, this is one of the best custom home builders Austin that delivers extraordinary results, improving both property value and owners’ lifestyle.

Those who wish to build a luxurious new home or transform their existing property can schedule a consultation with Bryan Murphy and take the first step toward creating their dream home, with one of the leading Austin custom home building contractors. Using the expertise of Murphy and his impeccable team, BLDR is redefining residential luxury and coming up with living spaces that are the epitome of high-end living in Austin.

About BLDR

BLDR was founded in 2013 by Bryan Murphy, the go-to custom home building contractor in Austin for clients seeking customized luxury residences with exceptional quality, timeless design, and personalized service. Specializing in crafting exquisite, tailor-made residences, it is committed to bringing clients’ visions to life with precision and sophistication.

Media Contact

Organization: BLDR

Contact Person: Bryan Murphy

Website: https://bryanmurphybuilder.com/

Email: Send Email

Contact Number: +15125474952

City: Austin

State: Texas

Country:United States

Release id:30778

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BLDR is the Premier Choice for Custom Home Building in Austin Ensuring Unmatched Luxury

This content is provided by a third-party source. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release.

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Press Release

222 Websites Named Best Website Designer Charleston by Best of Best Review

Published

47 minutes ago

July 15, 2025

Cloud PR Wire

222 Websites has been named Best Website Designer Charleston by Best of Best Review for 2025, recognizing their excellence in web design, SEO strategy, and small business digital marketing.

CHARLESTON, WV, United States, 15th Jul 2025 – 222 Websites has earned the title of Best Website Designer Charleston by Best of Best Review. The prestigious title confirms the firm’s effective use of search engine strategies and its commitment to boosting brand awareness. The recognition derives from consistent positive feedback from clients who appreciate the company’s focus on reaching the right target audience and its impact on revenue growth. With a clear focus on modern design techniques and actionable client feedback, 222 Websites has set itself apart as a leader. The accolade is a testament to their understanding of the digital space, particularly using search engine insights to drive tangible improvements for every business. Readers can explore more at https://bestofbestreview.com/awards/222-websites-best-website-design-agency-in-charleston-of-2025

222 Websites Named Best Website Designer Charleston by Best of Best Review

Strengthening Digital Strategies for Enhanced Engagement

222 Websites continues to refine its approach to website design and digital marketing based on detailed client feedback and effective search engine tactics. The company leverages modern design solutions to improve brand awareness, ensuring the digital presence of businesses aligns with the needs of their target audience. Detailed performance reviews support an approach that directly impacts revenue growth, combining innovative techniques with classic marketing fundamentals. Clients are encouraged to use the company’s services to see how a robust digital presence can amplify customer engagement and yield improved results. The strategy revolves around understanding client feedback and market responses, ensuring that every design choice translates to a positive influence on brand awareness and revenue. The clear connection between targeted audience analysis and search engine practices has helped businesses improve overall performance.

Driving Business Success Through Dedicated Digital Marketing

Recognized as Best Website Designer Charleston by Best of Best Review, 222 Websites continues to innovate within the digital marketing sphere. The company’s emphasis on market research, accessibility, budget, well-informed client feedback and strategic search engine practices directly contributes to higher revenue figures and improved brand awaress for their customers, really definining their reputation. Specialized services available at https://222websites.com focus on delivering custom website designs that effectively reach the target audience while ensuring a seamless user experience across the internet. Through continuous upgrades and close monitoring of search engine trends and exceptional project management standards, the company tailors its approach to meet the dynamic requirements of its diverse client base. This recognition by an esteemed review platform demonstrates the firm’s commitment to results-driven services, where every user experience design focused element is created to maximize exposure and gather positive feedback. By employing modern tactics in web applications and technology, and constant optimization by web developers, the company delivers measurable promotional benefits to its clients in lead generation, user experience, customer engagement, and critical built in tools and upgrades like email marketing, social media marketing, domain name registration, and other custom digital marketing services. The enhanced digital presence nurtures ongoing audience engagement, culminating in significant revenue improvements. Businesses seeking to strengthen their online identity now have a dependable partner in 222 Websites, a firm known for its professional approach and steadfast commitment to the evolving digital marketing landscape.

The agency also offers support with Wordpress Site Management, Information Management, devops, artificial intelligence, web design content creation, logo design services, landing page design, keyword research, increasing web traffic though seo, database management, web presence consultations, online image improvement, and more usint their engineering methodology and data based development and decision making in everything they offer.

About

222 Websites crafts affordable, fully managed small business websites and search marketing services. For inquiries or additional details, interested parties are encouraged to contact the company directly.

Company: 222 Websites
Website: https://222websites.com
Address: 222 Capitol St SUITE 522
Email: info@222websites.com
Phone: +1 (304) 484-4229
Media Email: info@222websites.com

Who reviewed the 222 websites named Best Website Designer Charleston?

The 222 websites were assessed by a team of skilled digital marketing professionals and web design specialists known for their expertise in small business online presence. You can learn more on the award page here: https://bestofbestreview.com/awards/222-websites-best-website-design-agency-in-charleston-of-2025

What criteria determine the best of best review selections?

Criteria for the charleston website design award included visual integrity, usability, effective SEO performance, customer engagement, and measurable returns from search marketing investments, ensuring our top agency website design services offered small business websites that attract and retain the right audience. When deciding who to award for the best web design charleston 2025 these were all taken into consideration

Does the review focus on affordable solutions for small businesses?

Yes, our review spotlights inexpensive, fully managed website creation, web design services,and search marketing services for small business owners at 222 websites web design firm. Tailored solutions for law firms, HVAC companies, roofing services, and more offer efficiency and growth.

Are Charleston web design agencies experienced in online marketing services?

Charleston web designers like 222 Websites offer seasoned support for online marketing with affordable small business website creation. web hosting services, content management systems, conversion rate optimization, and SEO optimization expertise, ensuring your business connects with the right customers without the hassle traditional methods often bring.

How can businesses benefit from these website design review ratings?

Website design review ratings enable business owners to assess service quality, improve digital marketing strategies, and boost online visibility, ultimately attracting more customers and driving revenue.

222 Websites

222 Capitol St SUITE 522, Charleston, WV 25301, United States

+13044844229

https://www.222websites.com/

Media Contact

Organization: 222 Websites

Contact Person: 222 Websites

Website: https://222websites.com/

Email: Send Email

Contact Number: +13044844229

Address:222 Capitol St SUITE 522, Charleston, WV 25301, United States

City: CHARLESTON

State: WV

Country:United States

Release id:30768

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Press Release

SENECA Digital Launches Bespoke Local SEO Services in Cork

Published

47 minutes ago

July 15, 2025

Cloud PR Wire

SENECA Digital, a Cork-based agency, has launched tailored local SEO services for small and medium-sized businesses across Cork City and County.

Cork City, Ireland (July 14, 2025) – In a city experiencing an exciting wave of growth, regeneration, and business optimism, SENECA Digital has announced the launch of a bold new suite of local SEO solutions designed specifically for small and medium-sized businesses (SMBs) across Cork City and County. As a homegrown agency deeply embedded in the Cork business landscape, SENECA Digital aims to empower local enterprises to compete online—whether they’re B2B service providers, artisan shops, professional practices, or new hospitality venues.

SENECA Digital Launches Bespoke Local SEO Services in Cork

Recent news from Cork reinforces the importance of a strong digital presence for local businesses. From Clancy’s Bar’s €500,000 renovation and relaunch on Princes Street to Tesco’s announcement of 100 new Cork jobs, it’s clear that the city is primed for economic momentum. But while footfall is rising on the streets, many Cork SMBs still struggle to get seen where it counts most: online.

“Our mission is simple,” says Daniel Connolly, founder of SENECA Digital. “We help Cork businesses rank higher on Google so they get discovered by real customers—whether that means showing up in Maps, outranking a competitor, or turning a few good reviews into a wave of new business. Local SEO isn’t just about keywords—it’s about trust, consistency, and being found at the right moment.”

To connect with Daniel directly, visit his LinkedIn profile: https://www.linkedin.com/in/danielconnollycork/, call 086-8228502, or email daniel@seneca.ie.

Top 10 Local SEO Services Provided by SENECA Digital

1. Google Business Profile (GBP) Optimisation

Example: “Atlantic Roofers Cork” – a roofing company in Ballincollig wants to rank for “roof repairs near me.” SENECA rewrites their business description, adds updated opening hours, services like “flat roof repairs,” and geo-tagged photos. They also add FAQs and posts promoting seasonal deals.

2. Local Keyword Research & Content Planning

Example: “Cork Print & Design”, a print shop near UCC, is losing business to online competitors. SENECA identifies that “student poster printing Cork” and “same-day business cards” are untapped keyword niches. They write landing pages targeting those keywords and update the homepage accordingly.

3. Review Generation & Management

Example: “Leeside Physio Clinic” in Douglas has 2 reviews and a 3.5-star rating. SENECA creates a review request automation via SMS and email post-visit. After 2 months, the clinic grows to 35 five-star reviews, pushing them into Google’s local 3-pack and increasing bookings by 42%.

4. On-Page SEO & Local Landing Page Design

Example: “Mallow Vet Centre” operates across two towns but their site has only one contact page. SENECA creates separate “Vet in Mallow” and “Vet in Kanturk” landing pages, each with unique content, contact info, and local testimonials.

5. Citation Building (Local Directories & Listings)

Example: “O’Shea Solicitors” in Midleton has inconsistent NAP (Name, Address, Phone) info across the web. SENECA standardises their listings and adds them to 20+ directories, boosting their local SEO signals and trust with Google.

6. Local Link Building

Example: “The Green Pantry”, a zero-waste grocer in Cork’s Victorian Quarter, partners with a local sustainability blog to run a “Plastic-Free July” campaign. SENECA helps write a press release and gets it published with a backlink, improving domain authority.

7. GBP Posting & Local Offers

Example: “Togher Tyres” runs a “Winter Tyre Safety Check” promo. SENECA schedules weekly posts on their GBP for November and December, adds high-quality photos, and links to a booking page. This drives new customer calls directly from Maps searches.

8. Local SEO Audits & Competitive Tracking

Example: “Cork Electricians 24/7” wonders why they’re ranking #5 while their rival shows in the top 3. SENECA runs a full audit revealing their competitor has double the reviews and better mobile site speed. SENECA builds a recovery plan that includes fixes.

9. Structured Data & Local Schema Implementation

Example: “Harbour Dental Care” in Cobh wants their patient reviews to show in search results. SENECA adds schema markup to highlight reviews in Google snippets, improving their click-through rate.

10. Local Ads for GBP & Maps Visibility

Example: “Blackrock Personal Trainers” wants leads within 5km. SENECA sets up a Google Maps ad campaign that runs only for users searching “gyms near me” within that area. Their CTR improves by 60%