Connect with us

Press Release

The PolkaStar—From the “Planet” Trade to the “Galaxy” Trade

Published

5 years ago

on

Half a year after the Polkadot mainnet was launched, known as the “Ethereum Killer,” it immediately ranked among the top ten cryptocurrencies by market capitalization. Its unparalleled capital and technical strength have not only been recognized by developers from all walks of life, but also by investors. Favored, the market reacted strongly. Previously, many industry experts at home and abroad have successively published a lot of opinions on the development direction of blockchain. Among them, there are three points about the summary of cross-chain technology, namely “blockchain interoperability”, “ease of use” and ” Scalability”.

As DeFi (decentralized finance) has exploded from Ethereum with a market value of up to 20 billion U.S. dollars since 2020, and recently BTC has risen to 30,000 U.S. dollars, these three mountains make people urgently need a mature Cross-chain technology, because the market value of DeFi almost only exists in Ethereum, and BTC, which accounts for 66% of the total market value of the blockchain, cannot release its huge vitality.

If we want to connect all the public chains together, instead of isolated islands of information, the hidden wealth behind it can only be exploited with the help of mature cross-chain technology.

Fortunately, in the second half of 2020, the Polkadot ecosystem led by Ethereum co-founder Gavin Wood has made great progress. The 100-parachain 1000-person verification plan has been completed by 70%, and the Polkadot system has 1.02 billion. DOT is worth about 6 billion U.S. dollars, of which about 3.7 billion U.S. dollars have been staking. In just 6 months, Polkadot has become the largest network pledged by capital value.

Perhaps we can cheer, the real cross-chain era is finally here!

Based on the cross-chain consensus NPOS mechanism, the PolkaStar development team from the United States has embarked on the path of being a strong man from the beginning. When other aggregators are still struggling to find prey on a public chain, they have a rich blockchain PolkaStar, which has experience in investment management, has focused on several public chains and made full use of Polkadot’s native interoperability, which is the most basic structure for arbitrage.

Among all the current blockchains, only PolkaStar has started the aggregation arbitrage on polkadot. Through the parallel chain design, communication coordination, transaction and authentication management are carried out simultaneously to achieve rapid arbitrage.

This is like, from the begining, people can only do business on one planet, and now they can do business on multiple planets without limit. Not only the market has become bigger, the products have increased, and the trade volume has also increased exponentially. The significance of this for ordinary investors is that they can get the maximum profit through an optimal investment portfolio as much as possible.

From a functional point of view, the financial products on the parachain will be the core role of the Polkadot ecology, mainly creating various financial products to enrich the Polkadot ecology and increase the value of the blockchain network, while the fisherman of the PolkaStar is responsible for monitoring the new According to the conditions and constraints of the contract, the most suitable product is selected for nomination, and finally the data is integrated into arbitrage after verification by the smart contract.

The development team of PolkaStar believes that the blockchain should not be a financial game for the minority and elites, but an inclusive finance with the Internet of everything.

At present, there are many decentralized financial products that blockchain investors can choose. Take Staking as an example. Ordinary investors must first reach a higher threshold to participate, and they will often not be able to achieve the best price in subsequent operations. Or the lowest slippage can get more profits, and in the current blockchain world, not only the pledge yield is very low (as low as 4.9%), frequent operations also exploit the income due to the pledger, transaction fees, gas fees, etc. The decrease in value flow caused by it is also the loss of the pledger, which urgently needs a “network” that produces an optimization effect.

So, can the world’s first low-value pledged, automatic interest-bearing PolkaStar cross-chain aggregator change the current situation of investment difficulties and slow financial management for ordinary investors?

Up to now, the number of projects deployed in the Polkadot network is about to reach 300. As the star DeF project among them, PolkaStar has built a complete DeFi operating system based on Polkadot’s Substrate framework. The homogeneous parallel chains in the Polkadot ecosystem can be Directly access the DeFi application in the PolkaStar system, and support PolkaStar’s affiliate tokens and financial primitives through the XCMP inter-chain communication protocol, providing users with more investment opportunities and maximizing the savings income based on the PolkaStar stablecoin.

According to the PolkaStar developer, by connecting to the Polkadot network to become a parachain, the design of the parachain has further improved operational efficiency, improved cross-chain communication problems, and provided investors with more financial project solutions on the chain. Improve operability, so as to obtain more and faster arbitrage opportunities.

PolkaStar aims to provide users with the best source of liquidity. The partnership with the Polkadot ecosystem can accelerate the realization of this goal. Once the PolkaStar-Ethereum bridge is activated, DeFi users will be able to take advantage of PolkaStar’s fast transaction speed and lower The gas cost to complete the transaction.

PolkaStar can be regarded as a fund management company in the traditional financial market. The traditional fund team makes portfolio investment through human judgment to obtain income, while PolkaStar replaces the centralized management team through smart contracts, which is decentralized. In cross-chain financial products, the best and most suitable points are constantly searched for transactions to expand the income, and the income obtained is then distributed to participating investors according to the distribution principle.

PolkaStar uses the fully modular and flexible Substrate tool to mix and match off-the-shelf components and build core business logic, while the rest is left to the framework, which can realize direct communication arbitrage between different blockchains, which is equivalent to entering from a local area network With the Internet, different individuals and regions can be connected to each other until all individuals are connected together, which greatly improves the efficiency of value transfer and truly achieves inclusive finance.

Therefore, the entry threshold of PolkaStar is much lower than that of ordinary DeFi, and the operation is more close to the people. Through PolkaStar’s inter-chain communication scheduling, investors can automatically find the decentralized financial products with the highest yield through established smart contracts and participate in the acquisition of top mines. Profiteering. On the other hand, you can also enjoy the dividends of other chains brought by the PolkaStar cross-chain mechanism, which ensures that the system can discover the process of quickly obtaining arbitrage opportunities in time and strive for more profits for users.

PolkaStar allows rapid information transmission and communication between all parachains. The PolkaStar Communication Bridge monitors the information transmission between all parachains and obtains the fastest prompt; automatic pledge to quickly occupy and pledge the defi project, in fast arbitrage circulation of first ore between each parallel chain. Let the value be realized quickly.

From the perspective of ease of use, in the entire aggregation system, PolkaStar’s main supervision and control object is the financial products on the parachain. These various financial products are used to enrich the Polkadot ecology and increase the value of the blockchain network. The PolkaStar will form an automated financial system that monitors the operation of the latest DeFi system on all chains, communicates and dispatches directly at the right time, and the smart contract will automatically seize the first mining opportunity and automatically carry out mining arbitrage under preset conditions. Use the fastest speed and trading strategy to obtain profits in various DeFi projects.

All of these are circulated on a transparent chain. PolkaStar has built a complete positive circulation system to enable more and more people to participate. The more cross-chain financial networks that PolkaStar enables, such as cross-chain lending and transactions. The more DAPPs such as, liquidity mining, synthetic assets, futures, options, etc. run, the robustness and arbitrage space of the network will be better and greater. This is the guarantee of the prosperity of the entire PolkaStar system, and at the same time fast The network and arbitrage space also ensure the continuous and stable growth of the entire system.

2021 is meant to be the year of cross-chain domination!

The founder of Polkadot hopes to create a more general and abstract model to solve some of the problems in the blockchain industry, with the goal of “Make blockchain great again”. The vision of PolkaStar, which has advantages in technology and ideas, is: “Let blockchain finance radiate vitality!

The first step is PolkaStar to build a decentralized aggregate DeFi arbitrage system, and quickly establish a cross-chain DeFi mortgage interest generation, arbitrage monitoring, and income settlement system.

The Polkadot Galaxy will bring the interoperability of the network to a new level. It will be a brand new cross-chain operating system that supports the cross-chain interaction of other chain DAPP projects. By aggregating various decentralized financial derivatives, it provides a complete operating platform for the entire blockchain network. And create a new ecology. Become a new way of expressing the value flow of blockchain.

As ordinary investment and financial planners and blockchain practitioners, we can also look forward to the different things that PolkaStar developed based on cross-chain technology can bring, so that everyone has the opportunity to participate in the blockchain. From the ordinary “planet” trade expand to the “galaxy” trade, and finally achieve the real inclusive finance!

About Author

Alex Jacob

Alex Jacob is a literature author. He was born in Chicago. Alex passion is writing news articles. He writes number of articles and published it.

See author's posts

Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.

Related Topics:
Continue Reading

Press Release

CMS (867/8A8): NDA of Innovative Drug Y-3 for Injection for Acute Ischemic Stroke Accepted in China

Published

5 hours ago

on

December 11, 2025

By

SHENZHEN, CHINA – China Medical System Holdings Limited (the “Group” or “CMS”) is pleased to announce that on 11 December 2025, the New Drug Application (NDA) of Class 1 Innovative Drug Y-3 for Injection (proposed English generic name: Loberamisal for Injection) (“Y-3 for Injection” or the “Product”) has been accepted by National Medical Products Administration of the People’s Republic of China (NMPA). The Product is a brain cytoprotectant indicated for the treatment of acute ischemic stroke.

 

With well-defined targets and clear mechanism of action, Y-3 for Injection is able to exert multiple therapeutic effects. As the world’s first brain cytoprotectant developed based on the important targets PSD95-nNOS and MPO, in the pathological processes of stroke, Y-3 for Injection acts on multiple key pathological processes of the ischemic cascade in ischemic stroke. Through multi-target, highly selective synergy, it is more conducive to exerting brain cytoprotective effects. The Product has an excellent therapeutic effect on ischemic stroke and the potential to prevent post-stroke depression and anxiety symptoms.

 

Y-3 for Injection demonstrates excellent clinical data with excellent efficacy and a favorable safety profile. The results of Phase II clinical trial of the Product in China indicated that among patients with ischemic stroke within 48 hours of onset, patients in the Y-3 group (40mg, qd) demonstrated a significantly higher proportion of patients achieving an excellent functional outcome (mRS of 0-1) at 90 days than those in the placebo group, with a rate difference of 16%. The Phase III clinical trial of the Product in China was conducted by Beijing Tiantan Hospital, Capital Medical University as the leading site. It has enrolled nearly 1,000 patients with acute ischemic stroke within 48 hours of onset across approximately 40 research centers nationwide, aiming to evaluate the efficacy and safety of Y-3 for Injection in treating patients with acute ischemic stroke within 48 hours of onset. The Phase III clinical study met the primary efficacy endpoint, with patients achieving significant clinical benefits and an overall favorable safety profile. The key study results are planned to be presented at international academic conferences, and the full study will be published in international academic journals.

 

The Central Nervous System (CNS) is one of the core advantageous fields of CMS, where a deeply integrated layout has been progressively established. The product portfolio has solidified the market foundation, including the marketed innovative drug VALTOCO (Diazepam Nasal Spray), the original brand drug Deanxit (Flupentixol and Melitracen Tablets), and the improved new drug ZUNVEYL (Benzgalantamine Gluconate Enteric-coated Tablets), which is currently under NDA review. The addition of Y-3 for Injection will further strengthen the product portfolio, generating highly efficient synergies in terms of expert networks and market resources. It is expected that if approved for marketing, Y-3 for Injection will bring a new generation of brain cytoprotectant with excellent efficacy and more comprehensive therapeutic effects to Chinese patients with ischemic stroke. Leveraging the successful commercialization experience and compliant and efficient operation system, the Group will accelerate the accessibility of innovative therapies to benefit more patients.

 

More Information about Y-3 for Injection

The pathological processes of acute ischemic stroke are highly complex and interconnected. There is an urgent clinical need for multi-target, multi-mechanism coordinated interventions to achieve more effective regulation of the complex ischemic cascade, thereby improving treatment outcomes and enhancing patients’ quality of life. Y-3 for Injection is able to uncouple PSD95-nNOS, inhibit MPO activity, and enhance the activity of α2-GABAA receptor (a subtype of GABAA receptor with antidepressant and anxiolytic effects). With this multi-target, highly selective synergistic mechanism, it is expected to achieve a technological breakthrough in the simultaneous intervention of “stroke treatment and prevention of post-stroke depression and anxiety”, making Y-3 for Injection a promising novel brain cytoprotectant with excellent efficacy and more comprehensive therapeutic effects.

 

The results of Phase II clinical trial of Y-3 for Injection for the treatment of acute ischemic stroke were presented as an oral poster at the 10th European Stroke Organisation Conference in 2024 (ESOC 2024). It indicated that among patients with ischemic stroke within 48 hours of onset, patients in the Y-3 group (20mg, 40mg, 60mg, qd) demonstrated a significantly higher proportion of patients achieving an excellent functional outcome (mRS of 0-1) at 90 days than those in the placebo group (20mg: 67.8% vs 60.7%, 40mg: 76.7% vs 60.7%, 60mg: 70.0% vs 60.7%). Moreover, the Product showed comparable safety to placebo in acute ischemic stroke patients, exhibiting good tolerability.

 

On 24 August 2023, the Group through its wholly-owned subsidiary entered into a Collaboration Agreement (the “Agreement”) with Neurodawn Pharmaceutical Co., Ltd. (“NeuroDawn”), a clinical needs-oriented pharmaceutical company driven by innovation and R&D. In accordance with the Agreement, the Group obtains an exclusive promotion right in mainland China, the Hong Kong Special Administrative Region, and the Macau Special Administrative Region. The term of the Agreement is permanent.

 

About Stroke

According to the Guideline for Prevention and Treatment of Cerebrovascular Disease (2024 Edition) issued by the National Health Commission, approximately 3.94 million new stroke cases occur in China each year, accounting for one-third of the global new cases[1]. Among these, ischemic stroke accounts for about 72%, with over 2.8 million new cases annually; the number of existing stroke patients in China has exceeded 28 million[1]. Data from China’s cause-of-death monitoring in 2021 shows that stroke-related deaths accounted for 23% of the national total deaths[1]. Over the past three decades, the disease burden of stroke-related disabilities in China has continued to increase[1]. Coupled with factors such as the accelerating aging of the population, the pressure of stroke prevention and control will further intensify in the future, posing enormous challenges to patients’ families and society[1]. In addition, post-stroke depression and anxiety are common complications of stroke, with incidence rates of approximately 30% and 25% respectively[2]. They can hinder the recovery of patients’ neurological functions, even increase the risk of death, and severely affect patients’ prognosis. Y-3 for Injection holds significant potential value for the long-term neurological function improvement and overall prognosis of a vast number of stroke patients, indicating broad market prospects.

 

About CMS

CMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet medical needs.

 

CMS focuses on the global first-in-class (FIC) and best-in-class (BIC) innovative products, and efficiently promotes the clinical research, development and commercialization of innovative products, enabling the continuous transformation of scientific research into clinical practices to benefit patients.

 

CMS deeply engages in several specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to promote the in-depth development in its advantageous specialty fields, strengthening the competitiveness of the cardio-cerebrovascular/ gastroenterology/ ophthalmology/ skin health businesses, bringing economies of scale in specialty fields. Among them, the skin health business (Dermavon) has become a leading enterprise in its field, and is proposed to be listed independently on the SEHK. Meanwhile, CMS continuously promotes the operation and development of its integrated R&D, manufacturing and commercialization chain in Southeast Asia and the Middle East, capturing growth opportunities in emerging markets to support the high-quality and sustainable development of the Group.

 

Reference

  1. National Health Commission of the People’s Republic of China. Guideline for Prevention and Treatment of Cerebrovascular Disease (2024 Edition) [J]. Chinese Journal of Magnetic Resonance Imaging, 2025, 16(1): 1-8. DOI: 10.12015/issn.1674-8034.2025.01.001.
  2. Chen Xinyu, Lyu Xiaohan, Li Ruina, et al. Post-Stroke Anxiety [J]. International Journal of Cerebrovascular Disease, 2022, 30(2): 129-133. DOI: 10.3760/cma.j.issn.1673-4165.2022.02.010.

 

CMS Disclaimer and Forward-Looking Statements

This press release is not intended to promote any products to you and is not for advertising purposes. This press release does not recommend any drugs, medical devices and/or indications. If you want to know more about the diagnosis and treatment of specific diseases, please follow the opinions or guidance of your doctor or other medical and health professionals. Any treatment-related decisions made by healthcare professionals should be based on the patient’s specific circumstances and in accordance with the drug package insert.

 

This press release which has been prepared by CMS does not constitute any offer or invitation to purchase or subscribe for any securities, and shall not form the basis for or be relied on in connection with any contract or binding commitment whatsoever. This press release has been prepared by CMS based on information and data which it considers reliable, but CMS makes no representation or warranty, express or implied, whatsoever, and no reliance shall be placed on, the truth, accuracy, completeness, fairness and reasonableness of the contents of this press release. Certain matters discussed in this press release may contain statements regarding the Group’s market opportunity and business prospects that are individually and collectively forward-looking statements. Such forward-looking statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties and assumptions that are difficult to predict. Any forward-looking statements and projections made by third parties included in this press release are not adopted by the Group and the Company is not responsible for such third-party statements and projections.

 

 

Media Contact

Brand: China Medical System Holdings Ltd.

Contact: CMS Investor Relations

Email: ir@cms.net.cn

Website: https://web.cms.net.cn/en/home/

About Author

Cloud PR Wire

See author's posts

Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.

Continue Reading

Press Release

Kevin Wall of Worcester Encourages Greater Civic Engagement Around Civil Liberties

Published

6 hours ago

on

December 11, 2025

By

Worcester, Massachusetts, 11 Dec 2025, ZEX PR WIRE, As debates over privacy, free speech, and policing continue to unfold nationwide, local residents like Kevin Wall of Worcester are encouraging more community awareness around civil liberties and individual rights.

Wall, who has lived in Worcester for over a decade, says many people care about these issues but don’t always know where to start. “Most people I talk to want things to be fair and transparent,” Kevin Wall said. “They’re concerned about surveillance, about how schools handle discipline, about what kind of data companies and the government collect. But they don’t always feel equipped to speak up.”

Though not affiliated with any organization, Wall often shares resources from civil rights groups like the ACLU, especially those related to Massachusetts policies and digital rights. He follows court decisions and legislative changes and encourages others to do the same. “You don’t have to be an expert. Just being informed helps you spot when something isn’t right.”

In Massachusetts, recent civil liberties conversations have included facial recognition technology bans, school-based surveillance tools, bail reform, and expanded voting access. Organizations like the ACLU of Massachusetts have weighed in on many of these issues, publishing legal analysis and policy recommendations.

Worcester itself has seen growing interest in these topics. In recent years, the city has hosted forums on data privacy, transparency in school policies, and police oversight. Wall sees this as a sign of a more engaged public. “It’s not about being political,” he said. “It’s about understanding how systems work and making sure people are treated fairly.”

He says the rise of AI and digital tracking tools has made the public role more important than ever. “The tools are changing fast. You need people who are paying attention and asking questions.”

Wall is particularly focused on issues that affect everyday life: student discipline policies, use of technology in public spaces, and due process protections in local courts. “You can’t protect your rights if you don’t know what they are,” he said. “Groups like the ACLU do a good job breaking it down.”

For Worcester residents looking to get more involved, Wall recommends starting small. “Read a case summary. Sign up for an email list. Go to a local meeting. Even asking questions at a school board or city council meeting makes a difference.”

While he doesn’t speak publicly or run a group, Wall believes that quiet civic engagement still matters. “There are lots of ways to contribute without being front and center.”

He hopes more residents in Worcester will take interest in how rights are shaped and protected at the local level. “We all benefit when more people pay attention. Whether it’s about speech, privacy, education, or equal treatment, these issues affect all of us.”

About Author

Cloud PR Wire

See author's posts

Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.

Continue Reading

Press Release

Kevin Wall Worcester: Local Voices Add Perspective as Civil Liberties Take Center Stage

Published

6 hours ago

on

December 11, 2025

By

Worcester, Massachusetts, 11 Dec 2025, ZEX PR WIRE, From school board meetings to courtroom challenges, the conversation around civil liberties in America is evolving. In cities like Worcester, residents such as Kevin Wall are quietly helping keep those conversations alive.

Wall isn’t a politician or spokesperson. He’s a longtime Worcester resident who takes an active interest in civil rights and regularly shares articles and legal updates with friends and neighbors. He says staying informed is part of being a responsible member of the community. “It’s not about having all the answers,” he said. “It’s about knowing enough to ask the right questions.”

Across the country, major civil liberties issues are in the spotlight—digital surveillance, student speech, reproductive rights, and access to public records among them. The ACLU and other legal groups continue to play a key role in shaping public understanding and defending constitutional protections.

Wall keeps tabs on this work, particularly from the ACLU of Massachusetts. “They’re one of the groups that actually explains things in plain language,” he said. “I follow their email briefings and court updates.”

In Worcester, topics like facial recognition, police transparency, and equity in school discipline have generated local interest. Wall believes these conversations are healthier when more people feel empowered to participate. “When you understand your rights, you’re more likely to speak up,” he said. “And when regular people speak up, public systems tend to work better.”

Although Wall doesn’t attend public events or speak on panels, his role is more grassroots. He brings up civil liberties topics in everyday conversation and encourages others to learn more. “People are surprised by how much these things touch their lives—how a policy might affect their kid at school or the way local police handle data.”

He’s especially concerned about how fast technology is changing the landscape. “AI tools, data collection, automated decisions—these are things that need public oversight,” Wall said. “You don’t need to be paranoid, but you should know what’s happening.”

Wall represents a growing number of residents who take an interest in public life without making it their job. “Not everyone wants to go to rallies or run for office,” he said. “But that doesn’t mean they don’t care. Being informed is a kind of participation.”

The ACLU continues to advocate for strong protections around voting access, LGBTQ+ rights, free expression, and immigration policy—many of which have direct implications for Worcester residents. Wall believes that raising awareness is a shared responsibility. “Organizations can only do so much. People need to take that extra step—read more, talk more, think more critically.”

As legal and political battles continue across the country, local voices like Kevin Wall’s reflect a broader truth: civil liberties aren’t just an issue for lawyers and lawmakers. They belong to everyone. And in Worcester, more residents are starting to take notice.

About Author

Cloud PR Wire

See author's posts

Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.

Continue Reading

LATEST POST

Like Us
Follow Us
Subscribe Us
Follow Us