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One Year Into Kabir Naths Leadership, Compass Pathways (NASDAQ: CMPS) Phase 3 Trial For Innovative Treatment Resistant Depression Progressing

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1 week ago

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–News Direct–

By Faith Ashmore, Benzinga

Treatment-resistant depression, also referred to as TRD, is a subset of depression that poses significant challenges for clinicians, patients and those closest to patients. It is characterized by persistent symptoms of depression that do not respond adequately to at least two different standard antidepressant treatments. This debilitating condition often leaves individuals grappling with feelings of despair, hopelessness and a diminished quality of life.

Unlike some forms of depression that may improve with pharmacological interventions or talk therapies, TRD tends to persist, leading to a multitude of negative consequences. The unyielding nature of this condition can contribute to increased rates of disability, higher suicide risk and significant financial burden due to the need for repeated treatments. Psilocybin treatment is emerging as a potentially effective approach to the treatment of TRD.

Although further research is still needed to establish its efficacy and safety, initial findings are promising. While there are a number of companies developing psilocybin treatments, Compass Pathways (NASDAQ: CMPS) is setting itself apart from its contemporaries with its phase 3 program in TRD.

The companys innovative approach has received FDA Breakthrough Therapy designation in the U.S. and Innovative Licensing and Access Pathway designation in the U.K. for their investigational COMP360 psilocybin. Moreover, in late 2021, Compass Pathways announced the completion of a randomized, controlled double-blind phase 2b study of COMP360 psilocybin treatment involving 233 patients with TRD in 22 sites across Europe and North America.

In August of 2022, Compass Pathways brought on Kabir Nath as CEO to help navigate its transition from a start-up to an established phase 3 biopharma company. Nath is a seasoned healthcare executive with over two decades of experience leading global pharmaceutical companies. He has held several leadership positions at multinational corporations, including Bristol Meyers Squibb (NYSE: BMS), GlaxoSmithKline (NYSE: GSK) and Otsuka Pharmaceutical (OTCMKTS: OTSKY).

Nath has a track record of success in developing new products and creating commercial strategies to make medicines available to patients on a global scale. He is skilled in identifying unmet patient needs and working collaboratively with stakeholders to develop targeted and effective treatment options. He also has considerable experience in psychiatric drug development.

Under Naths leadership, Compass Pathways has made significant progress in advancing the development of its investigational drug, COMP360 psilocybin. One notable accomplishment was the initiation of their phase 3 clinical trials, which are pivotal in determining the safety and efficacy of the treatment. These trials consist of two key studies: Pivotal Trial 1 (COMP005) and Pivotal Trial 2 (COMP006).

COMP005 is studying a single dose (25mg) of COMP360 psilocybin as monotherapy, comparing it with a placebo. The aim of this trial is to replicate the positive treatment response observed in the companys phase 2b study, which included 233 patients with treatment-resistant depression.

COMP006 is a fixed repeat dose monotherapy study that examines the effects of three different dose arms: 25mg, 10mg and 1mg. The objective of this trial is to investigate whether a second dose can enhance the number of responders and further improve the response observed in the phase 2b study. Additionally, this trial explores the potential for a meaningful treatment response from the repeat administration of COMP360 10mg.

Both pivotal trials have the change from baseline in MADRS (Montgomery-sberg Depression Rating Scale) total score at week six as their primary endpoint. This measure allows researchers to evaluate the effectiveness of COMP360 psilocybin in reducing depressive symptoms compared to baseline.

In addition to driving the company forward into phase 3, Nath has supported the development of the companys digital platforms that accompany its psilocybin treatment, has led a successful private placement fundraising that extends the companys runway into late 2025, and claims to have one of the most talented and experienced leadership team among psychedelic companies in the space. Nath's global experience in the pharmaceutical industry and his expertise in developing and commercializing treatments for unmet needs uniquely position him to lead Compass Pathways toward the successful development and commercialization of their investigational drug COMP360 psilocybin, subject to FDA approval.

Company BioCOMPASS Pathways plc (Nasdaq: CMPS) is a mental health care company dedicated to accelerating patient access to evidence-based innovation in mental health. Our focus is on improving the lives of those who are suffering with mental health challenges and who are not helped by current treatments. We are pioneering the development of a new model of psilocybin therapy, in which our proprietary formulation of synthetic psilocybin, COMP360, is administered in conjunction with psychological support. COMP360 has been designated a Breakthrough Therapy by the U.S. Food and Drug Administration (FDA) and has received Innovative Licensing and Access Pathway (ILAP) designation in the UK for treatment-resistant depression (TRD). We have commenced a phase 3 clinical program of COMP 360 psilocybin therapy in TRD, the largest randomised, controlled, double-blind psilocybin therapy clinical program ever conducted. Previously, we completed a phase 2b study with top line data showing a statistically significant (p<0.001) and clinically relevant improvement in depressive symptom severity after three weeks for patients who received a single high dose of COMP360 psilocybin with psychological support. We are also conducting phase 2 clinical studies of COMP360 psilocybin therapy for post-traumatic stress disorder (PTSD) and anorexia nervosa. COMPASS is headquartered in London, UK, with offices in New York and San Francisco in the United States. Our vision is a world of mental wellbeing.

This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice.

Contact Details

Stephen Schultz

[email protected]

View source version on newsdirect.com: https://newsdirect.com/news/one-year-into-kabir-naths-leadership-compass-pathways-nasdaq-cmps-phase-3-trial-for-innovative-treatment-resistant-depression-progressing-838899400

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Press Release

The Fusion of Fashion and Technology: Adi Cohen’s “Anywear” Revolution

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12 mins ago

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September 29, 2023

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An extraordinary event is on the horizon in the world of fashion!

United States, 29th Sep 2023, King NewsWire – On October 15th, 2023, the fashion realm is gearing up for a captivating journey. Anywear Design proudly announces the debut of the ‘Anywear Design Contest’; a competition aimed at celebrating creativity, passion, and envisioning the future of fashion.

This contest stands out as a peerless platform for up-and-coming designers, fashion aficionados, and those who appreciate the artistry in clothing. It offers an opportunity to present designs that not only encapsulate the essence of fashion but also pave the way for innovative trends.

More than just a competition, it’s a beckoning to innovation and artistic expression in the apparel industry. For those keen on participating or following this event closely, details can be found at: www.anywear.online

ANYWEAR DESIGN

In a world of fleeting fashions and cyclical trends, fashion is undergoing a seismic shift thanks to luminaries like Adi Cohen. This visionary, behind “Anywear”, has brought to light a brilliant blend of cutting-edge technological solutions with sustainable fashion showcases.

Redefining the Fashion Landscape: Venturing into the realm of fashion, Cohen didn’t settle for the status quo. She identified a niche where individual desires could be realized through bespoke fashion. Launched aggressively in 2016, “Anywear” wasn’t about birthing just another brand; it was about spearheading a movement. This movement wasn’t about a transient style but about enduring elegance tailored to personal tastes, championing a sustainable ethos.

Artisanal Sustainability: Every Stitch Tells a Story: The conventional fashion model revolves around mass-produced designs that quickly fall out of fashion, adding to the ever-growing landfill issues. “Anywear” stands as an antithesis to this. Every outfit, tailored to personal preferences, ensures minimal waste. Through this revolutionary model, attire isn’t about fleeting allure but valued pieces that stand the test of time.

The Future of Fashion Meets Technology: Imagine a world where your wardrobe can be digitally designed and physically produced within the confines of your home. Cohen’s vision marries AI, augmented reality, and 3D printing, heralding a future where the boundary between the digital and the physical becomes blurred. Under her leadership, “Anywear” is making this future accessible, pushing the boundaries of what’s possible in fashion.

Tech Revolution in Fashion: Adi Cohen and “ANYWEAR”

Fashion has always been a reflection of society and its evolution. But today, thanks to visionaries like Adi Cohen, the industry is on the brink of an unprecedented revolution. Cohen, with her brand “Anywear”, is merging cutting-edge technology with sustainability, introducing the world to a new fashion paradigm.

Eco-Innovation: A Commitment to the Planet: Environmental consciousness has become critical for the current generations. Cohen grasped this and set out to ensure that “Anywear” wasn’t just a fashion brand but a badge of responsibility. Using recycled materials and eco-friendly production processes, the brand

stands out not just for its style but its commitment to the planet.

AI and Customization: A Potent Mix: In the age of personalization, consumers no longer want to be just another number. They seek products that echo their individuality. “Anywear”, with its integration of artificial intelligence, allows its customers to design and tailor their clothes, offering unique pieces that truly mirror the wearer’s personality.

Adi’s Vision: Beyond Fashion: For Cohen, “Anywear” isn’t just a business. It’s a mission. A mission to show that fashion can be responsible, sustainable, and simultaneously chic and avant-garde. With plans to take her brand global, Cohen hopes “Anywear” can set a benchmark for other emerging brands and businesses.

Conclusion: In an ever-changing world, where technology and fashion intersect, brands like “Anywear”, led by visionaries like Adi Cohen, are showing the way forward. A path where sustainability, personalization, and innovation go hand in hand.

www.anywear.online

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Organization: Anywear Design

Contact Person: Cristian Alvarez

Website: https://anywear.online/

Email: [email protected]

Country: United States

Release Id: 2909236690

The post The Fusion of Fashion and Technology: Adi Cohen’s “Anywear” Revolution appeared first on King NewsWire. It is provided by a third-party content provider. King Newswire makes no warranties or representations in connection with it.

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Press Release

Touch of Smart: Your Destination for Fast Shipping, High-Quality, and Affordable Products

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12 mins ago

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September 29, 2023

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United States, 29th Sep 2023, King NewsWire – Touch of Smart, a leading online retailer, is revolutionizing the way consumers shop for high-quality products with its commitment to fast 4-day US shipping, top-notch quality, and unbeatable affordability. Catering to the needs of modern shoppers, Touch of Smart is the ultimate destination for those seeking an exceptional shopping experience.

Fast 4-Day US Shipping:

In today’s fast-paced world, waiting weeks for an online purchase to arrive can be a frustrating experience. Touch of Smart understands the importance of prompt delivery. That’s why we offer fast 4-day US shipping on a wide range of products. We believe in delivering not just products but also convenience and peace of mind to our customers.

High Quality:

Quality is the cornerstone of Touch of Smart’s philosophy. We handpick products from reputable manufacturers, ensuring they meet stringent quality standards. Our commitment to excellence is reflected in every item we offer. Whether it’s electronics, home and kitchen essentials, health and fitness equipment, or fashion accessories, we provide products that are built to last and perform exceptionally.

Affordable Prices:

At Touch of Smart, we believe that everyone deserves access to high-quality products at affordable prices. Our competitive pricing strategy allows us to offer incredible value to our customers. We understand the importance of budget-friendly options without compromising on quality. By keeping our prices low, we make it possible for our customers to enjoy the best without breaking the bank.

Explore Our Product Categories:

Discover the Touch of Smart difference by exploring our diverse product categories. From cutting-edge electronics to stylish fashion, we have something for everyone. Whether you’re looking for the latest gadgets, stylish clothing, or innovative home and kitchen solutions, you’ll find it at Touch of Smart.

As part of this press release, we are delighted to introduce you to one of our featured products: the Product Category. This product exemplifies our commitment to quality, affordability, and fast shipping.

Media Contact

Organization: Touch of smart

Contact Person: Touch of smart Team

Website: https://touchofsmart.com/

Email: [email protected]

Country: United States

Release Id: 2909236691

The post Touch of Smart: Your Destination for Fast Shipping, High-Quality, and Affordable Products appeared first on King NewsWire. It is provided by a third-party content provider. King Newswire makes no warranties or representations in connection with it.

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Press Release

Touch of Smart Sets New Standards with Fast Shipping, Unmatched Quality, and Affordable Prices

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12 mins ago

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September 29, 2023

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United States, 29th Sep 2023, King NewsWire – Touch of Smart, a pioneering online retail destination, is elevating the shopping experience with its unwavering commitment to fast 4-day US shipping, superior quality, and budget-friendly prices. In a world where convenience, quality, and savings are paramount, Touch of Smart emerges as the go-to choice for discerning consumers.

Fast 4-Day US Shipping:

Long gone are the days of anxiously awaiting online orders for weeks. Touch of Smart believes that prompt delivery is not just a service but a promise. With fast 4-day US shipping, we ensure that our customers receive their purchases swiftly and efficiently, reducing wait times and enhancing the overall shopping experience.

Uncompromising Quality:

Quality is the cornerstone of Touch of Smart’s ethos. We meticulously curate our product selection, partnering only with reputable manufacturers who meet our stringent quality standards. Our unwavering commitment to excellence is evident in every item we offer, whether it’s cutting-edge electronics, home essentials, fitness equipment, fashion, or pet products.

Affordable Prices:

At Touch of Smart, we firmly believe that high-quality products should be accessible to everyone, regardless of their budget. We’ve taken a customer-centric approach by offering competitive pricing that ensures affordability without compromising quality. Our aim is to empower our customers to make smart choices for their everyday needs while staying within their financial means.

Discover Our Product Categories:

Explore the diverse world of Touch of Smart through our extensive product categories. From state-of-the-art electronics to fashionable attire and innovative pet solutions, we cater to a wide range of consumer needs. As part of this announcement, we are thrilled to introduce you to one of our featured product categories: Dog Carriers & Travel Products. This collection embodies our commitment to quality, affordability, and quick delivery.

Media Contact

Organization: Touch of smart

Contact Person: Touch of smart Team

Website: https://touchofsmart.com/

Email: [email protected]

Country: United States

Release Id: 2909236692

The post Touch of Smart Sets New Standards with Fast Shipping, Unmatched Quality, and Affordable Prices appeared first on King NewsWire. It is provided by a third-party content provider. King Newswire makes no warranties or representations in connection with it.

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Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.

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