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CMS (867.HK, 8A8.SG) Reports Growth in Revenue and Profit for H1 2025, Strategic Transformation Unlocks New Drivers

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4 months ago

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SHENZHEN, CHINA – On 18 August, China Medical System Holdings Limited (“CMS” or the “Company”) announced its interim results for the six months ended 30 June 2025 (the “Reporting Period”), with both revenue and profit recording year-on-year growth, demonstrating the initial results of its strategic transformation. During the Reporting Period, the Company recorded revenue of approximately RMB4.00 billion, representing a year-on-year increase of 10.8%. In the case that all medicines were directly sold by the Company, revenue would be approximately RMB4.67 billion, up 8.9% year-on-year. Net profit was approximately RMB0.93 billion, representing an increase of 3.1% year-on-year.

The results reflect that CMS has emerged from the shadow of National Volume-based Procurement (“National VBP”), and its performance is expected to return to a sustainable growth trajectory. Revenue from the Company’s key non-National VBP exclusive/branded products and innovative products (in the case that all medicines were directly sold by the Company) reached approximately RMB2.90 billion, up 20.6% year-on-year, accounting for 62.1% of total revenue. The company’s exclusive/branded products and innovative products have a favorable competitive landscape and high visibility of future growth, and have now become the main drivers of performance growth.

According to the interim results announcement, the company has been planning its “New CMS” blueprint since 2018, anchored on the three strategic pillars of “product innovation, commercial model reform, and international expansion” to build a sustainable second growth curve. By the first half of 2025, solid operating results and the steady delivery of innovation outcomes have confirmed that the Company’s strategic upgrade has been gradually translated into tangible achievements.

“New Products” Strategy Drives Innovation Value Realization and Solidifies Growth Momentum

At the forefront of the Company’s three strategic pillars, the “product innovation” strategy leverages a three-dimensional innovation mechanism of “overseas licensing, domestic collaboration, and in-house R&D” to continuously inject high-value short-, medium- and long-term pipelines, serving as a key growth engine. Currently, the innovation strategy has entered a period of continuous harvest, with new products continuously releasing commercial and clinical value.

To date, the Company has successfully commercialized five innovative drugs in China; By 2025, two innovative products — ruxolitinib cream and Desidustat Tablets—are also expected to receive marketing approvals. Ruxolitinib cream is the first and only topical JAK inhibitor approved by the U.S. FDA and the European Medicines Agency for repigmentation in non-segmental vitiligo, and is expected to become the first approved treatment for vitiligo in China, filling a market gap and bringing new hope to Chinese vitiligo patients. Additionally, the New Drug Application (NDA) for the Alzheimer’s disease drug ZUNVEYL in China was accepted in July this year; the consumer healthcare product Poly-L-lactic Acid Microparticle Filler Injection has been approved for marketing, further enriching the Company’s diversified product portfolio.

Among the innovative pipeline under R&D, several blockbuster candidates have entered the late-stage clinical development in China and are expected to be commercialized within the next one to three years, forming a new driving force for sustained growth.

Among these, the collaborative product Y-3 for Injection has completed Phase III clinical trials in China. This product is an original unimolecular Class 1 innovative drug and the only non-peptide PSD95/nNOS uncoupler that has entered clinical development, with potential to become the first dual-function brain cytoprotectant for treating ischemic stroke while preventing post-stroke depression and anxiety. Another oral small molecule Class 1 innovative drug, ABP-671 (a URAT1 inhibitor) for the treatment of gout and hyperuricemia, is progressing through Phase IIb/III clinical trials in China. Compared with existing mainstream drugs, ABP-671 has the potential to reduce uric acid to lower levels at lower doses and possesses gout-tophus dissolution capability, thereby offering patients a more effective and safer treatment option.

CMS continues to expand its innovative pipeline and enhance its end-to-end innovation capabilities to ensure the steady, phased marketing approval of innovative products. In H1 2025, two new collaborative R&D innovative products — ZUNVEYL and MG-K10 (a long-acting anti-IL-4Rα humanized monoclonal antibody injection) — were added to the portfolio. To date, the Company has deployed about 40 differentiated innovative pipeline products, including approximately 20 in-house R&D projects.

 

Advancing “New Models” and “New Markets” Strategies to Unlock Multi-dimensional Growth

According to the interim results announcement, CMS continues to advance its “New Models — Commercial Model Reform” strategy, forging anti-cyclical resilience through a diversified ecosystem. It also firmly implements its “New Markets – International Expansion” strategy, building a multi-dimensional growth framework via an industrial internationalization model.

Under the commercial model reform strategy, the Company continues to focus on specialty therapeutic fields while expanding into new retail and new media channels, building a comprehensive marketing and promotion system that covers both “in-hospital + out-of-hospital” and “online + offline” channels, and reinforcing its diversified product portfolio with consumer attributes. Its skin health business, Dermavon, has demonstrated strong potential in this particular segment with consumer attributes. Since its independent operation in 2021, Dermavon has achieved dual leadership in both the “coverage of dermatology indications” and the “revenue scale of dermatological prescription drugs”, and is proposed to be spun off and separately listed on the Main Board of the Hong Kong Stock Exchange by way of introduction and distribution in specie, to further unlock its standalone value and high-growth potential.

In terms of internationalization, CMS successfully completed its secondary listing on the Main Board of the Singapore Exchange by way of introduction on 15 July 2025, marking a new milestone in its “industrial internationalization” strategy. With Singapore as a hub, the Company has established a comprehensive business system covering the entire value chain of “R&D–Manufacturing–Commercialization” for emerging markets. To date, its commercial platform company, Rxilient, has cumulatively submitted nearly 20 registration applications for pharmaceutical products and medical devices across Southeast Asia, the Middle East, Hong Kong, Macau, and Taiwan Region, covering therapeutic fields such as dermatology, ophthalmology, oncology, autoimmune, and central nervous system. Ruxolitinib cream (vitiligo indication) has been approved for marketing in Macau and Hong Kong, and its registration applications have been submitted in Singapore and Taiwan Region. Intravenous Toripalimab (the first China-originated anti-PD-1 monoclonal antibody drug that has been approved by the China NMPA and the U.S. FDA) has been submitted for registration in five countries, including Malaysia. Tildrakizumab Injection and Sucroferric Oxyhydroxide Chewable Tablets have also been approved for marketing in Hong Kong. Meanwhile, PharmaGend, an associate CDMO manufacturing facility in which CMS holds a 45.0% equity interest, now has an annual production capacity of 1 billion units of oral solid dosage forms (tablets and capsules), and has obtained a drug manufacturing license from Singapore’s HSA, U.S. FDA cGMP certification, and passed Swiss QP audits. The construction of new production lines for nasal sprays, creams, and injectables is progressing steadily, providing high-standard production and delivery capabilities for the international market.

Looking ahead, the growth logic of “New CMS” is expected to accelerate its realization, with profitability and performance resilience improving simultaneously. The Company is building a growth framework centered on differentiated innovation, driven by a synergistic and diversified ecosystem, and underpinned by an international footprint. This will open up long-term opportunities for high-quality development, deliver quality pharmaceutical products and services to patients worldwide, and generate sustainable returns for shareholders.

 

About CMS

CMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet medical needs.

 

CMS focuses on the global first-in-class (FIC) and best-in-class (BIC) innovative products, and efficiently promotes the clinical research, development and commercialization of innovative products, enabling the continuous transformation of scientific research into clinical practices to benefit patients.

 

CMS deeply engages in several specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to promote the in-depth development of its advantageous specialty fields and expand business boundaries, strengthening the competitiveness of the cardio-cerebrovascular/gastroenterology/ophthalmology/ skin health businesses. Among them, the skin health business has become a leading enterprise in its field, bringing economies of scale in specialty therapeutic fields. Meanwhile, CMS continuously deepens its business development in the Southeast Asia and Middle East regions, further escorting the sustainable and healthy development.

 

CMS Disclaimer and Forward-Looking Statements

This press release is not intended to promote any products to you and is not for advertising purposes. This press release does not recommend any drugs, medical devices and/or indications. If you want to know more about the diagnosis and treatment of specific diseases, please follow the opinions or guidance of your doctor or other medical and health professionals. Any treatment-related decisions made by healthcare professionals should be based on the patient’s specific circumstances and in accordance with the drug package insert.

 

This press release which has been prepared by CMS does not constitute any offer or invitation to purchase or subscribe for any securities, and shall not form the basis for or be relied on in connection with any contract or binding commitment whatsoever. This press release has been prepared by CMS based on information and data which it considers reliable, but CMS makes no representation or warranty, express or implied, whatsoever, and no reliance shall be placed on, the truth, accuracy, completeness, fairness and reasonableness of the contents of this press release. Certain matters discussed in this press release may contain statements regarding the Group’s market opportunity and business prospects that are individually and collectively forward-looking statements. Such forward-looking statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties and assumptions that are difficult to predict. Any forward-looking statements and projections made by third parties included in this press release are not adopted by the Group and the Company is not responsible for such third-party statements and projections.

 

Media Contact

Brand: China Medical System Holdings Ltd.

Contact: CMS Investor Relations

Email: ir@cms.net.cn

Website: https://web.cms.net.cn/en/home/

Source: China Medical System Holdings Ltd.

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KeyCrew Media Selects ACME Real Estate as Verified Expert for Boutique Brokerage Operations, and LA Market Expertise

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8 hours ago

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December 13, 2025

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KeyCrew Media, a real estate analytics and media network, has selected Courtney Poulos and her team at ACME Real Estate as a KeyCrew Verified Expert.

LOS ANGELES, CA, December 12, 2025 — KeyCrew Media, a real estate analytics and media network, has selected Courtney Poulos and her team at  ACME Real Estate as a KeyCrew Verified Expert. The boutique Los Angeles brokerage will contribute specialized insights on renovation-resale strategy, boutique brokerage operations, and LA market dynamics.

KeyCrew Verified Experts are carefully selected as prolific market trend authorities who demonstrate exceptional insight and expertise in their fields. These distinguished professionals and companies regularly contribute market insights, expert perspectives, and forward-looking analysis to help audiences navigate complex industry landscapes.

Founded in 2011 by Broker/Owner Courtney Poulos, ACME Real Estate has established itself as a premier boutique brokerage specializing in renovation-resale projects across Los Angeles. Operating in what Poulos calls “the NFL of real estate,” ACME has built its reputation on comprehensive agent training, ethical accountability, and exceptional client experiences without the backing of international capital funding.

ACME Real Estate offers a distinctive “one-stop shop” approach for real estate investors and renovation-resale specialists. The brokerage provides full-spectrum support from acquisition—including deal analysis and cost-benefit evaluation—through in-house design services at any price point, sophisticated appraisal packaging, and premium marketing. With 35 agents completing 178 transaction sides totaling $155 million in sales volume over the past 12 months, ACME has proven that boutique brokerages can compete against corporate giants through superior training and service.

“We’re honored that ACME Real Estate has been selected as a KeyCrew Verified Expert,” said Courtney Poulos, Broker/Owner. “We built ACME to fill a gap in the market—highly trained agents who the public can trust, comprehensive support for renovation-resale investors, and a commitment to quality over scale. This recognition validates what our clients already know: sometimes the underdogs deliver the highest quality service.”

ACME Real Estate’s areas of expertise include:

  • Renovation-Resale Strategy – Comprehensive acquisition analysis, cost estimation, design consultation, and resale marketing for investors
  • Boutique Brokerage Operations – Building and scaling quality-focused independent brokerages in competitive markets
  • Los Angeles Market Dynamics – Deep expertise in LA neighborhoods, market trends, and investment opportunities
  • Agent Training & Development – Mastery-based training programs emphasizing contract expertise and client psychology
  • Premium Property Marketing – High-end photography, printed materials, and strategic positioning for maximum market performance

About ACME Real Estate

ACME Real Estate is a boutique independent brokerage founded in 2011 and based in Los Angeles. With 35 agents and 178 transaction sides totaling $155 million in sales volume over the past 12 months, ACME specializes in renovation-resale projects and provides comprehensive support from acquisition through marketing and sale. The brokerage offers in-house design services at any price point, sophisticated appraisal packaging, and premium marketing execution. ACME serves both real estate investors and traditional buyers and sellers with what Broker/Owner Courtney Poulos describes as “the most concierge, attentive, well-trained group of underdogs you could ever have behind you.” Website: https://acmeflorida.com/

About KeyCrew Media

KeyCrew Media is the next generation real estate intelligence platform that leverages AI-powered analytics and first-person reporting from verified experts to produce forward-looking insights across local markets and niche asset classes. Proprietary market reporting is delivered through KeyCrew’s growing portfolio of niche media properties—including KeyCrew Journal, NextAsset News, and other specialized publications—as well as selectively syndicated to media partners that influence industry decision-makers. Learn more at keycrew.co

Media Contact

Organization: KeyCrew Media

Contact Person: Heather Hook

Website: https://www.keycrew.co

Email: Send Email

City: Baltimore

State: Maryland

Country:United States

Release id:39011

The post KeyCrew Media Selects ACME Real Estate as Verified Expert for Boutique Brokerage Operations, and LA Market Expertise appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section

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KeyCrew Media Selects Brooke Pfautz as Verified Expert for Vacation Rental Management and Property Technology

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8 hours ago

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December 13, 2025

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KeyCrew Media, a real estate analytics and media network, has selected Brooke Pfautz, CEO and Founder of Vintory, as a KeyCrew Verified Expert.

NATIONWIDE, December 12, 2025 — KeyCrew Media, a real estate analytics and media network, has selected Brooke Pfautz, CEO and Founder of Vintory, as a KeyCrew Verified Expert. Pfautz will contribute data-driven analysis on vacation rental management, property technology innovation, and industry consolidation trends.

KeyCrew Verified Experts are carefully selected as prolific market trend authorities who demonstrate exceptional insight and expertise in their fields. These distinguished professionals regularly contribute market insights, expert perspectives, and forward-looking analysis to help audiences navigate complex industry landscapes.

Brooke Pfautz brings unparalleled expertise to the vacation rental management sector, having helped over 950 companies scale their portfolios through strategic growth initiatives. As founder of both Vintory and Comparent, Pfautz has established herself as a leading voice on data-driven property acquisition, AI integration in hospitality operations, and market consolidation dynamics. Her work encompasses the largest database of vacation rental homeowners globally and the industry’s first comprehensive ranking system through the Comparent 100.

With 18 years of experience in the short-term rental industry, Pfautz successfully scaled Vantage Realty to over 500 properties before its acquisition. She has since focused on revolutionizing how professional vacation rental managers approach growth through Vintory’s data and marketing platform, which aggregates information from over 10 sources to create what she calls “stacked data architecture” — a proprietary approach that provides unprecedented accuracy in homeowner targeting.

Pfautz’s insights on artificial intelligence adoption have positioned her as a forward-thinking industry authority. She advocates that property managers not implementing AI-native tools by 2026 risk competitive obsolescence, emphasizing that data capture — particularly call recordings and guest communications — represents the critical intellectual property that will differentiate winners in an increasingly AI-driven marketplace.

“I’m honored to be selected as a KeyCrew Verified Expert,” said Brooke Pfautz. “The vacation rental management industry is at a pivotal moment where data quality and AI adoption will separate thriving companies from those left behind. Having helped nearly 1,000 companies with their growth strategies, I’ve seen firsthand how the right data and technology stack can transform a mid-sized operator into a market leader. I’m excited to share insights that help property managers navigate consolidation pressures, leverage their unique data assets, and position themselves strategically whether they’re scaling independently or preparing for acquisition.”

Pfautz’s areas of expertise include:

  • Vacation Rental Management Growth Strategies — Proven frameworks for inventory acquisition and scaling beyond 10 million in gross bookings
  • Property Technology & AI Integration — Strategic guidance on AI-native tools, data architecture, and competitive positioning
  • Market Consolidation & M&A Dynamics — Insights on institutional capital trends, acquisition metrics, and positioning for exit
  • Homeowner Data & Marketing Analytics — Expertise in multi-source data aggregation, targeting precision, and marketing ROI optimization

About Vintory

Vintory is a data, sales, and marketing platform that helps professional vacation rental managers grow their inventory through the world’s largest database of vacation rental homeowners. The platform combines proprietary stacked data architecture with tech-enabled marketing services, building targeted campaigns that drive qualified leads through custom CRM and automation systems. Vintory has supported over 950 property management companies with strategic growth initiatives. Website: www.vintory.com

About KeyCrew Media

KeyCrew Media is the next generation real estate intelligence platform that leverages AI-powered analytics and first-person reporting from verified experts to produce forward-looking insights across local markets and niche asset classes. Proprietary market reporting is delivered through KeyCrew’s growing portfolio of niche media properties — including KeyCrew Journal, NextAsset News, and other specialized publications — as well as selectively syndicated to media partners that influence industry decision-makers. Learn more at keycrew.co

Media Contact

Organization: KeyCrew Media

Contact Person: Heather Hook

Website: https://www.keycrew.co

Email: Send Email

City: Baltimore

State: Maryland

Country:United States

Release id:39013

The post KeyCrew Media Selects Brooke Pfautz as Verified Expert for Vacation Rental Management and Property Technology appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section

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KLOTA Launches Two Free Analysis Tools to Help E-Commerce Brands Improve Search and AI Visibility

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11 hours ago

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December 13, 2025

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Sweden, 13th Dec 2025 – KLOTA AB, a Sweden-based digital performance and SEO consultancy, has announced the launch of two new free analysis tools designed specifically for serious e-commerce companies seeking stronger visibility, better performance, and clearer insights across search engines and AI-driven platforms. The newly released tools—the AI Visibility Analyzer and the Shopping Feed Analyzer—are currently available as free BETA services and deliver actionable results within approximately 10 minutes via email.

As search behavior rapidly evolves, e-commerce brands are no longer competing only for traditional Google rankings. Increasingly, consumers are discovering products and brands through AI-powered assistants such as ChatGPT, Claude, Perplexity, and Gemini. KLOTA’s new tools are built to address this shift, providing practical diagnostics that help online retailers understand where they stand and what to fix.

The AI Visibility Analyzer focuses on how well a website is seen, accessed, and understood by modern AI search engines and large language models. The tool evaluates critical factors such as AI-bot accessibility (including robots.txt and llms.txt), content clarity and readability, structured data, and core technical SEO elements. Based on this analysis, it generates an easy-to-understand AI Visibility Score ranging from 0 to 100, along with clear, prioritized recommendations that highlight the most impactful improvements.

“This is about helping companies prepare for the next generation of search,” said Anders Karlsson, Contact at KLOTA AB. “Many e-commerce brands are still optimizing only for classic search results, while AI assistants are already shaping how users discover information and products. The AI Visibility Analyzer makes this new landscape measurable and actionable.”

The second tool, the Shopping Feed Analyzer (Google Shopping Feed Analyzer ), is designed for e-commerce businesses actively running Google Shopping and Performance Max (PMax) campaigns. Poor feed quality is a common reason for disapproved products, limited reach, and underperforming ads. KLOTA’s tool performs an automated quality audit of a Google Shopping product feed , reviewing required attributes, product titles and descriptions, pricing accuracy, images, Google product categories, and overall compliance with Google’s specifications.

After the audit, users receive a detailed PDF report that includes an executive summary and a prioritized action list. This enables marketing and e-commerce teams to quickly identify errors, resolve disapprovals, and systematically improve feed quality for better campaign performance.

“Most feed issues are not strategic—they’re technical and fixable,” Karlsson added. “The challenge is knowing exactly where the problems are and what to address first. The Shopping Feed Analyzer removes that guesswork and gives teams a clear roadmap.”

Both tools are offered as free BETA services, reflecting KLOTA’s commitment to sharing expertise and helping e-commerce brands adapt to a more complex digital ecosystem. Once a website URL or product feed is submitted, the analysis is processed automatically and sent by email in about 10 minutes, making the tools accessible even for busy teams with limited technical resources.

While some information within the tools may be presented in English, the insights are designed to be universally applicable for international e-commerce brands aiming to compete more effectively in search, paid media, and AI-driven discovery.

With the launch of these tools, KLOTA reinforces its position as a forward-looking partner for e-commerce growth—bridging traditional SEO, paid shopping performance, and the emerging world of AI visibility.

For more information visit https://www.klota.se .

About KLOTA AB
KLOTA AB is a Sweden-based digital consultancy specializing in SEO, e-commerce optimization, and data-driven performance strategies. The company works with ambitious brands that want to improve visibility, traffic quality, and revenue across search engines, advertising platforms, and AI-powered discovery channels.

Media Contact

Organization: KLOTA AB

Contact Person: Anders Karlsson

Website: https://www.klota.se/

Email: Send Email

Address:Katrinedalsgatan 13A 504 51 BORÅS Sweden

Country:Sweden

Release id:39023

The post KLOTA Launches Two Free Analysis Tools to Help E-Commerce Brands Improve Search and AI Visibility appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section

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Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.

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