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China Medical System Gained Exclusive Commercialization Right of Class 1 Innovative Drug Targeting Gout and Hyperuricemia

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7 months ago

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SHENZHEN, CHINA – China Medical System Holdings Limited (the “Company”, together with its subsidiaries, the “Group” or “CMS”) is pleased to announce that on 2 December 2024, the Group through a wholly-owned subsidiary of the Company entered into an Exclusive Commercialization Agreement (the “Agreement”) with Atom Therapeutics Co., Ltd (hereinafter referred to as “Atom Therapeutics”, formerly named as “Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd.”) of class 1 innovative drug ABP-671 for the treatment of gout and hyperuricemia (the “Product”). In accordance with the Agreement, the Group is entitled to an exclusive commercialization right of the Product in Mainland China, Hong Kong Special Administrative Region and Macao Special Administrative Region. The term of cooperation commences on the effective date of the Agreement and extends for ten years from the date the Product is first approved for market launch in Mainland China (the “Authorization Term”). Upon the expiration of the Authorization Term, it may be automatically renewed for an additional ten years, subject to specific conditions stipulated in the Agreement.

 

ABP-671 is a class 1 innovative chemotherapeutic drug for the treatment of gout and hyperuricemia, currently in Phase 2b/3 clinical trials for gout in China and overseas. The Product reduces renal re-absorption of uric acid by inhibiting Urate Anion Transporter 1 (URAT1). The results of two completed phase 2 clinical trials demonstrated favorable efficacy and safety profiles across multiple dose groups (ranging from 1 mg to 12 mg) of ABP-671. The 2 mg once-daily dosage of the Product was proved to be as effective as, or even better than, benzbromarone or febuxostat (maximum dosage of 80mg). The reduction in uric acid levels was sustained throughout the 24-hour period, with no significant safety concerns identified. This product is anticipated to offer more effective and safer treatment alternatives for patients suffering from gout and hyperuricemia[1]. Multiple patents in regard to substance and use of the ABP-671 have been granted in China.

 

Hyperuricemia is defined as a fasting blood uric acid level exceeding 420μmol/L (7.0 mg/dL) in adults on a normal purine diet on two separate days. The deposition of urate crystals in hyperuricemia patient results in arthritis, medically termed gout. Hyperuricemia and gout can cause acute and chronic inflammatory injury in articular cartilage, bone, kidney and vascular wall, which can lead to multiple organ damage of the heart, brain and kidney, etc. The data presented in the White Paper on Hyperuric Acid and Gout Trends in China (2021) indicates that, the incidence rate of hyperuricemia is 13.3%, with approximately 177 million hyperuricemia patients and the incidence rate of gout is 1.1% in general, with about 14.66 million gout patients in China. Frost & Sullivan indicates that, the number of people with hyperuricemia and gout in China will continue to increase in the future, reaching 240 million and 52.2 million respectively by 2030. Currently, the commonly used uric acid-lowering drugs in clinical practice in China are those which inhibit uric acid synthesis or promote uric acid excretion. Due to certain limitations in the efficacy and safety of the marketed uric acid-lowering drugs, such as causing renal failure, sudden cardiac death or severe liver toxicity. There is still an urgent need for effective and safe uric acid-lowering drugs among gout and hyperuricemia patients in China.

 

ABP-671 is currently with the potential to be the promising and safe product for the treatment of gout and hyperuricemia. Through this collaboration, it fills the blank in the CMS’s product portfolio of the treatment of gout. Gout and hyperuricemia are both rheumatic diseases and chronic metabolic diseases, which are highly consistent with the Group’s strategic layout in the cardio-cerebrovascular/ gastroenterology business and the network resources of marketed products. If approved for marketing in the future, the Product will synergize with the Group’s marketed product Metoject (methotrexate injection) in rheumatology and with Elcitonin (elcatonin injection) in endocrinology and orthopedics, in terms of expert network and market resources. Based on the unmet clinical needs and the expected solid clinical data of the Product, the Group is looking forward to the smooth advancement of the clinical development of ABP-671, allowing patients with relevant indications to benefit from this innovative treatment sooner.

 

About ATOM THERAPEUTICS

Atom Therapeutics was founded in March 2012, focused on the research and development of innovative drugs with global commercial value and competitiveness in the metabolic and inflammatory area. Atom Therapeutics’s main core team members come from the United States, with extensive experience in the research and development of innovative drugs. Atom Therapeutics has achieved remarkable development in the past few years. Atom Therapeutics’s core product ABP-671 is under pivotal clinical stage for the treatment of chronic gout. Atom Therapeutics’s another small molecule innovative drug named as ABP-745, used for indications in the field of anti-inflammatory immune indications. The Phase 1 clinical of ABP-745 exhibited outstanding pharmacokinetics and safety. The clinical trial is on the verge of entering Phase 2. For more information about Atom Therapeutics and its pipeline, please visit https://www.atombp.com/.

 

About CMS

CMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet medical needs.

 

CMS focuses on the global first-in-class (FIC) and best-in-class (BIC) innovative products, and efficiently promotes the clinical research, development and commercialization of innovative products, enabling the continuous transformation of scientific research into clinical practices to benefit patients.

 

CMS deeply engages in several specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to promote the in-depth development of its advantageous specialty fields and expand business boundaries. While strengthening the competitiveness of the cardio-cerebrovascular/gastroenterology business, CMS independently operates its dermatology and medical aesthetics business, and ophthalmology business, aiming to gain leading positions in specialty therapeutic fields, whilst enhancing the scale and efficiency. At the same time, CMS has expanded its business territory to the Southeast Asian market, striving to become a “bridgehead” for global pharmaceutical companies to enter the Southeast Asian market, further escorting the sustainable and healthy development of the Group.

 

Reference:

  1. The results of Phase 2 clinical trials was published and can be found at: https://www.atombp.com/2023/03/01/atom-bioscience-announces-positive-results-of-phase-2a-china-clinical-trial-of-its-urat1-inhibitor-for-chronic-gout/

 

CMS Disclaimer and Forward-Looking Statements

This press release is not intended to promote any products to you and is not for advertising purposes. This press release does not recommend any drugs, medical devices and/or indications. If you want to know more about the diagnosis and treatment of specific diseases, please follow the opinions or guidance of your doctor or other medical and health professionals. Any treatment-related decisions made by healthcare professionals should be based on the patient’s specific circumstances and in accordance with the drug package insert.

 

This press release which has been prepared by CMS does not constitute any offer or invitation to purchase or subscribe for any securities, and shall not form the basis for or be relied on in connection with any contract or binding commitment whatsoever. This press release has been prepared by CMS based on information and data which it considers reliable, but CMS makes no representation or warranty, express or implied, whatsoever, and no reliance shall be placed on, the truth, accuracy, completeness, fairness and reasonableness of the contents of this press release. Certain matters discussed in this press release may contain statements regarding the Group’s market opportunity and business prospects that are individually and collectively forward-looking statements. Such forward-looking statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties and assumptions that are difficult to predict. Any forward-looking statements and projections made by third parties included in this press release are not adopted by the Group and the Company is not responsible for such third-party statements and projections.

 

Media Contact

Brand: China Medical System Holdings Ltd.

Contact: CMS Investor Relations

Email: ir@cms.net.cn

Website: https://web.cms.net.cn/en/home/

Source: China Medical System Holdings Ltd.

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Press Release

Iverol Introduces Modern eCommerce Platform Featuring a Wide Range of Must-Have Products

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13 minutes ago

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June 18, 2025

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United States, 18th Jun 2025 – In a world where online shopping is becoming the norm, Iverol is stepping into the spotlight as a fresh, modern, and customer-focused eCommerce platform. With a wide selection of trending, essential, and stylish products, Iverol offers an innovative shopping experience for anyone looking to save time while enjoying quality and value.

Created to serve a diverse customer base, Iverol is more than just a digital store—it’s a lifestyle destination. From home décor and personal gadgets to fashion items and everyday basics, the platform presents a seamless way to shop smart without sacrificing quality or convenience.

According to a spokesperson for Iverol, “Our mission is to simplify online shopping by offering everything customers need in one place. We combine affordability with reliability, while consistently updating our product selection to reflect what’s new, relevant, and in demand.”

A Marketplace Built for the Modern Shopper

Iverol’s clean, well-organized interface makes the online shopping experience intuitive and stress-free. Shoppers can quickly browse, filter, and purchase from a wide range of product categories, whether they are looking for personal essentials, gifts, or stylish upgrades for their home or wardrobe.

Categories available on the site include home and kitchen items, beauty and personal care, electronics, fashion accessories, wellness products, and more. New items are added regularly to ensure the catalog stays current and appealing to today’s shoppers.

The checkout process is secure, fast, and optimized for both desktop and mobile users. Customers can track their orders, access support, and manage their preferences from an easy-to-use dashboard.

Quality, Value, and Convenience

Iverol sets itself apart by prioritizing product quality and customer satisfaction. Each product is carefully selected to meet standards of functionality and appeal. Customers can shop confidently knowing that Iverol is committed to offering dependable products at reasonable prices.

The platform frequently runs promotions, bundles, and time-limited deals, making it easier for customers to enjoy top-tier items without stretching their budgets. Iverol also offers flexible return policies and responsive customer service, ensuring peace of mind with every order.

“Our customers don’t just want to shop—they want to feel good about what they’re buying,” the Iverol team explained. “That’s why we emphasize transparency, trust, and convenience in every part of the shopping journey.”

Evolving With Trends and Technology

Iverol leverages data and customer feedback to evolve its offerings and website features continuously. The platform tracks industry trends, seasonal needs, and user behavior to optimize the browsing experience and product selection.

This data-driven approach allows Iverol to stay ahead of the curve, delivering what customers want—even before they know they want it. The result is a modern, reliable, and engaging online marketplace built with the customer at its core.

About Iverol

Iverol is an emerging eCommerce brand dedicated to offering high-quality, affordable products across a variety of categories. The company’s online store combines convenience, innovation, and a strong focus on customer needs. With its growing product line, user-friendly website, and consistent deals, Iverol is quickly earning a place as a favorite online destination for savvy shoppers.

Discover more and shop online at https://iverol.com/

Media Contact

Organization: Iverol

Contact Person: Support Team

Website: https://iverol.com/

Email: Send Email

Country:United States

Release id:29368

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Iverol Introduces Modern eCommerce Platform Featuring a Wide Range of Must-Have Products

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Press Release

That Shawty Janiyah Collection Unveils Stylish and Affordable eCommerce Hub for All Ages

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13 minutes ago

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June 18, 2025

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United States, 18th Jun 2025– Fashion-forward, affordable, and made for everyone—That Shawty Janiyah Collection proudly announces the official launch of its dynamic online shopping platform. Built with a flair for trendsetting and inclusivity, the store brings together a curated blend of fashion, accessories, lifestyle goods, and home items, appealing to style-savvy shoppers across all age groups.

That Shawty Janiyah Collection is more than a brand; it’s a bold celebration of individuality and self-expression. Whether you’re seeking vibrant streetwear, chic handbags, cozy home décor, or must-have daily items, the platform delivers a personalized shopping experience that resonates with a diverse audience.

“Our goal was to create a digital space where people from all walks of life can find items that represent who they are—without breaking the bank,” said the founder of the brand. “We stand for bold style, quality products, and making everyone feel seen.”

A New Destination for Style and Everyday Needs

The eCommerce site is tailored for quick discovery, smooth browsing, and instant connection with the latest fashion and lifestyle trends. With categories designed to highlight both essential goods and statement pieces, That Shawty Janiyah Collection empowers customers to explore their unique tastes effortlessly.

Top site features include:

  • Stylish Clothing & Accessories for all genders and sizes
  • Home & Lifestyle Essentials curated with comfort and utility in mind
  • Affordable Pricing with Regular Deals and flash sales
  • Mobile-Optimized Experience for fast and fun shopping on the go

The vibrant design of the website reflects the brand’s energy—bold colors, intuitive filters, and rotating collections ensure each visit feels fresh and exciting.

Trend-Driven Collections for Every Season

One of the standout features of That Shawty Janiyah Collection is its dedication to keeping inventory relevant and on-trend. Seasonal collections and limited-time drops offer customers access to new items regularly, making each visit an opportunity to discover something new and inspiring.

Shoppers can find:

  • Signature apparel that blends comfort with charisma
  • Funky accessories, sunglasses, and bags
  • Versatile home goods and gift items perfect for any occasion
  • Items designed for all body types and age ranges

Inclusive, Accessible, and Customer-Focused

At its core, That Shawty Janiyah Collection champions inclusivity and realness. The platform features diverse models, accessible price points, and size-inclusive selections that ensure everyone feels welcome.

With robust customer support, easy returns, and multiple payment options, the platform is built to eliminate friction and elevate the joy of online shopping.

“It’s not just about what you wear or buy—it’s how you feel doing it,” the founder emphasized. “We want everyone to shop confidently, express themselves authentically, and leave our site feeling inspired.”

About That Shawty Janiyah Collection

That Shawty Janiyah Collection is a vibrant eCommerce brand offering fashion, lifestyle, and home essentials designed to celebrate individuality. Founded on the principles of inclusivity, affordability, and bold self-expression, the platform delivers products that speak to a wide range of tastes and needs. From everyday pieces to head-turning looks, the brand is building a digital community where every shopper feels empowered to be their full self.

Start shopping today at https://thatshawtyjaniyahcollection.com/

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Contact Person: Support Team

Website: https://thatshawtyjaniyahcollection.com/

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That Shawty Janiyah Collection Unveils Stylish and Affordable eCommerce Hub for All Ages

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Press Release

Popular Outlet Emerges as Go-To Online Store for Budget-Friendly Shopping and Top Deals

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13 minutes ago

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June 18, 2025

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United States, 18th Jun 2025  – As inflation continues to reshape consumer habits, budget-savvy shoppers are turning to smarter alternatives. Rising to meet this demand, Popular Outlet has officially launched as a premier online destination for quality products at unbeatable prices. With an expansive selection of items spanning fashion, electronics, beauty, and more, Popular Outlet offers the savings of an outlet store—without leaving your home.

Whether you’re furnishing a home, upgrading your tech, or simply looking to save on everyday items, Popular Outlet is tailored to make shopping easy, fun, and wallet-friendly. With weekly deals, flash discounts, and a wide product variety, the platform ensures that every customer finds something they love—at a price they can afford.

“We created Popular Outlet with one goal: to give everyday shoppers a smarter way to buy,” said a spokesperson for the brand. “Great deals shouldn’t mean compromising on quality or convenience, and that’s exactly what we deliver.”

Everyday Essentials, Extraordinary Savings

What makes Popular Outlet stand out is its commitment to blending affordability with quality. The site is stocked with thousands of products across essential categories, including:

  • Home & Kitchen
  • Clothing & Accessories
  • Electronics & Gadgets
  • Beauty & Personal Care
  • Gifts & Lifestyle Items

From limited-time markdowns to ongoing promotions, Popular Outlet empowers customers to shop smart, no matter the season or need.

Seamless Shopping for Everyone

Designed for speed and simplicity, the Popular Outlet platform is intuitive and mobile-friendly. The streamlined search tools, dynamic filters, and clear product descriptions ensure that visitors can find what they need with minimal effort. And with secure payment gateways and global shipping options, the store is accessible to a wide customer base worldwide.

Key features include:

  • Safe, Encrypted Checkout Process
  • Fast Shipping and Order Tracking
  • Customer-Centered Return Policies
  • Weekly Flash Deals & Email Exclusive Discounts

Customers also benefit from ongoing product updates and new arrivals, meaning there’s always something fresh to explore on the site.

A Store Designed with Shoppers in Mind

Popular Outlet listens to what customers want. The site regularly updates its inventory based on trends, customer reviews, and shopping behavior. With affordable luxury at its core, the brand ensures that shoppers no longer need to choose between style, function, and price.

The platform also runs loyalty incentives, encouraging repeat customers to enjoy even deeper discounts and early access to sales.

“Our mission is to make high-quality goods accessible to everyone,” said the brand team. “We’re not just another eCommerce store—we’re a resource for families, students, and anyone who wants more value from their money.”

About Popular Outlet

Popular Outlet is an online general store offering a vast selection of discounted, high-quality items. Built for modern consumers who value savings without sacrificing quality, Popular Outlet delivers everyday products at outlet prices. With secure shopping, dependable shipping, and constant new arrivals, the site is quickly becoming a favorite among online bargain hunters.

Find your next deal today at https://popularoutlet.shop/

Media Contact

Organization: Popular Outlet

Contact Person: Support Team

Website: https://popularoutlet.shop/

Email: Send Email

Country:United States

Release id:29367

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Popular Outlet Emerges as Go-To Online Store for Budget-Friendly Shopping and Top Deals

This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release.

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