Press Release
China Medical System Gained Exclusive Commercialization Right of Class 1 Innovative Drug Targeting Gout and Hyperuricemia
SHENZHEN, CHINA – China Medical System Holdings Limited (the “Company”, together with its subsidiaries, the “Group” or “CMS”) is pleased to announce that on 2 December 2024, the Group through a wholly-owned subsidiary of the Company entered into an Exclusive Commercialization Agreement (the “Agreement”) with Atom Therapeutics Co., Ltd (hereinafter referred to as “Atom Therapeutics”, formerly named as “Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd.”) of class 1 innovative drug ABP-671 for the treatment of gout and hyperuricemia (the “Product”). In accordance with the Agreement, the Group is entitled to an exclusive commercialization right of the Product in Mainland China, Hong Kong Special Administrative Region and Macao Special Administrative Region. The term of cooperation commences on the effective date of the Agreement and extends for ten years from the date the Product is first approved for market launch in Mainland China (the “Authorization Term”). Upon the expiration of the Authorization Term, it may be automatically renewed for an additional ten years, subject to specific conditions stipulated in the Agreement.
ABP-671 is a class 1 innovative chemotherapeutic drug for the treatment of gout and hyperuricemia, currently in Phase 2b/3 clinical trials for gout in China and overseas. The Product reduces renal re-absorption of uric acid by inhibiting Urate Anion Transporter 1 (URAT1). The results of two completed phase 2 clinical trials demonstrated favorable efficacy and safety profiles across multiple dose groups (ranging from 1 mg to 12 mg) of ABP-671. The 2 mg once-daily dosage of the Product was proved to be as effective as, or even better than, benzbromarone or febuxostat (maximum dosage of 80mg). The reduction in uric acid levels was sustained throughout the 24-hour period, with no significant safety concerns identified. This product is anticipated to offer more effective and safer treatment alternatives for patients suffering from gout and hyperuricemia[1]. Multiple patents in regard to substance and use of the ABP-671 have been granted in China.
Hyperuricemia is defined as a fasting blood uric acid level exceeding 420μmol/L (7.0 mg/dL) in adults on a normal purine diet on two separate days. The deposition of urate crystals in hyperuricemia patient results in arthritis, medically termed gout. Hyperuricemia and gout can cause acute and chronic inflammatory injury in articular cartilage, bone, kidney and vascular wall, which can lead to multiple organ damage of the heart, brain and kidney, etc. The data presented in the White Paper on Hyperuric Acid and Gout Trends in China (2021) indicates that, the incidence rate of hyperuricemia is 13.3%, with approximately 177 million hyperuricemia patients and the incidence rate of gout is 1.1% in general, with about 14.66 million gout patients in China. Frost & Sullivan indicates that, the number of people with hyperuricemia and gout in China will continue to increase in the future, reaching 240 million and 52.2 million respectively by 2030. Currently, the commonly used uric acid-lowering drugs in clinical practice in China are those which inhibit uric acid synthesis or promote uric acid excretion. Due to certain limitations in the efficacy and safety of the marketed uric acid-lowering drugs, such as causing renal failure, sudden cardiac death or severe liver toxicity. There is still an urgent need for effective and safe uric acid-lowering drugs among gout and hyperuricemia patients in China.
ABP-671 is currently with the potential to be the promising and safe product for the treatment of gout and hyperuricemia. Through this collaboration, it fills the blank in the CMS’s product portfolio of the treatment of gout. Gout and hyperuricemia are both rheumatic diseases and chronic metabolic diseases, which are highly consistent with the Group’s strategic layout in the cardio-cerebrovascular/ gastroenterology business and the network resources of marketed products. If approved for marketing in the future, the Product will synergize with the Group’s marketed product Metoject (methotrexate injection) in rheumatology and with Elcitonin (elcatonin injection) in endocrinology and orthopedics, in terms of expert network and market resources. Based on the unmet clinical needs and the expected solid clinical data of the Product, the Group is looking forward to the smooth advancement of the clinical development of ABP-671, allowing patients with relevant indications to benefit from this innovative treatment sooner.
Atom Therapeutics was founded in March 2012, focused on the research and development of innovative drugs with global commercial value and competitiveness in the metabolic and inflammatory area. Atom Therapeutics’s main core team members come from the United States, with extensive experience in the research and development of innovative drugs. Atom Therapeutics has achieved remarkable development in the past few years. Atom Therapeutics’s core product ABP-671 is under pivotal clinical stage for the treatment of chronic gout. Atom Therapeutics’s another small molecule innovative drug named as ABP-745, used for indications in the field of anti-inflammatory immune indications. The Phase 1 clinical of ABP-745 exhibited outstanding pharmacokinetics and safety. The clinical trial is on the verge of entering Phase 2. For more information about Atom Therapeutics and its pipeline, please visit https://www.atombp.com/.
About CMS
CMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet medical needs.
CMS focuses on the global first-in-class (FIC) and best-in-class (BIC) innovative products, and efficiently promotes the clinical research, development and commercialization of innovative products, enabling the continuous transformation of scientific research into clinical practices to benefit patients.
CMS deeply engages in several specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to promote the in-depth development of its advantageous specialty fields and expand business boundaries. While strengthening the competitiveness of the cardio-cerebrovascular/gastroenterology business, CMS independently operates its dermatology and medical aesthetics business, and ophthalmology business, aiming to gain leading positions in specialty therapeutic fields, whilst enhancing the scale and efficiency. At the same time, CMS has expanded its business territory to the Southeast Asian market, striving to become a “bridgehead” for global pharmaceutical companies to enter the Southeast Asian market, further escorting the sustainable and healthy development of the Group.
Reference:
- The results of Phase 2 clinical trials was published and can be found at: https://www.atombp.com/2023/03/01/atom-bioscience-announces-positive-results-of-phase-2a-china-clinical-trial-of-its-urat1-inhibitor-for-chronic-gout/
CMS Disclaimer and Forward-Looking Statements
This press release is not intended to promote any products to you and is not for advertising purposes. This press release does not recommend any drugs, medical devices and/or indications. If you want to know more about the diagnosis and treatment of specific diseases, please follow the opinions or guidance of your doctor or other medical and health professionals. Any treatment-related decisions made by healthcare professionals should be based on the patient’s specific circumstances and in accordance with the drug package insert.
This press release which has been prepared by CMS does not constitute any offer or invitation to purchase or subscribe for any securities, and shall not form the basis for or be relied on in connection with any contract or binding commitment whatsoever. This press release has been prepared by CMS based on information and data which it considers reliable, but CMS makes no representation or warranty, express or implied, whatsoever, and no reliance shall be placed on, the truth, accuracy, completeness, fairness and reasonableness of the contents of this press release. Certain matters discussed in this press release may contain statements regarding the Group’s market opportunity and business prospects that are individually and collectively forward-looking statements. Such forward-looking statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties and assumptions that are difficult to predict. Any forward-looking statements and projections made by third parties included in this press release are not adopted by the Group and the Company is not responsible for such third-party statements and projections.
Media Contact
Brand: China Medical System Holdings Ltd.
Contact: CMS Investor Relations
Email: ir@cms.net.cn
Website: https://web.cms.net.cn/en/home/
Source: China Medical System Holdings Ltd.
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
United States, 29th Apr 2025, – San Francisco, CA — In a world that’s increasingly disconnected from nature, GroundingTime is proud to unveil its latest innovation: the Bamboo Grounding Fitted Sheet | 5X Grounding Power for Better Sleep Groundingtime — a wellness-forward, eco-conscious sleep essential designed to bring the science of grounding into your bedroom, without compromising on style, softness, or sustainability.
Nature-Inspired, Science-Backed
Grounding, also known as earthing, is the practice of connecting your body directly to the Earth’s natural electric charge. Studies suggest that this connection may support better sleep, reduce inflammation, and promote a greater sense of calm and balance.
Our Bamboo Grounding Fitted Sheet is designed to help facilitate this connection — effortlessly. Using a proprietary blend of conductive silver fibers woven into ultra-soft bamboo fabric, the sheet connects via a grounding cord to a grounded outlet, helping your body naturally sync with the Earth’s energy while you sleep.
“We wanted to take The Science Behind Grounding Therapy | How Earth’s Energy Heals – Groundingtime and make it easy, beautiful, and accessible for everyone,” says the GroundingTime product design team. “This sheet is as much about comfort as it is about connection.”
Why Bamboo?
Unlike traditional cotton or synthetic fabrics, bamboo is naturally breathable, hypoallergenic, and antimicrobial. It also happens to be one of the most sustainable resources on the planet.
Each GroundingTime sheet is made from certified organic bamboo sourced from responsibly managed forests, ensuring minimal environmental impact while delivering maximum comfort.
Key Benefits of Bamboo:
Thermoregulating & breathable
Incredibly soft — even after multiple washes
Naturally moisture-wicking and odor-resistant
Hypoallergenic — ideal for sensitive skin
Built-In Multi-Point
Grounding Therapy | 5X Enhanced Grounding Technology – Groundingtime
What sets this sheet apart is its integrated grounding grid of pure silver threads. These threads are seamlessly woven into the fabric, allowing for safe and effective conductivity without sacrificing comfort.
The sheet comes with a grounding cord and adapter that easily connects to a standard grounded outlet, giving you the benefits of grounding while you sleep — with no need to change your habits or routines.
Functional Design That Fits Your Life
The Bamboo Grounding Fitted Sheet is available in multiple sizes, with 15‘’ deep-pocket corners that fit even oversized mattresses. It’s machine-washable, easy to set up, and designed to integrate smoothly with any bedroom aesthetic.
Whether you’re new to grounding or a long-time believer in the benefits, this sheet is a simple yet powerful addition to your wellness routine.
What Customers Are Saying
“I’ve been using the GroundingTime bamboo sheet for just two weeks, and I’ve noticed deeper, more restful sleep. The fabric is unbelievably soft — I honestly don’t want to get out of bed.”
— Laura M., verified buyer
“I’ve struggled with chronic pain in my lower back for years. After sleeping on the GroundingTime bamboo sheet for just a few nights, I woke up with noticeably less stiffness and tension. It’s the first thing I’ve tried that’s made a real difference — naturally.”
— Daniel R., verified buyer
Sustainability at the Core
GroundingTime believes that wellness shouldn’t come at the expense of the planet. That’s why every sheet is packaged in plastic-free, recyclable materials, and a portion of each purchase goes toward reforestation and clean water initiatives.
Availability
The Bamboo Grounding Fitted Sheet is now available exclusively at www.groundingtime.com, with free U.S. shipping.
About GroundingTime
GroundingTime combines scientific research with natural therapy to offer a gentle, nature-based wellness solution for those living with chronic conditions, pain, and sleep challenges. Through grounding technology, we help users reduce stress, improve rest, and support overall health and mind-body balance in everyday life.
Media Contact
Organization: GroundingTime
Contact
Person: Mona
Website:
https://groundingtime.com/
Email:
hello@groundingtime.com
Country:United States
The post GroundingTime Debuts Eco-Friendly Bamboo Grounding Sheet to Redefine Rest appeared first on
Brand News 24.
It is provided by a third-party content
provider. Brand News 24 makes no
warranties or representations in connection with it.
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
United States, 29th Apr 2025, – CozyBliss, an innovator in modern home lifestyle products, is excited to announce the launch of its 2025 COOLI PRO Cooling Bedding Collection, a next-generation comfort solution designed to deliver instant cooling and long-lasting comfort throughout the night. The new collection integrates a proprietary woven pattern and Sorona® bio-based fiber technology, offering a superior sleep experience rooted in both innovation and sustainability.
Sleep Cool and Comfortable with Sorona® Fiber
At the heart of the COOLI PRO comforters is advanced Sorona® fiber technology, engineered to enhance breathability and cooling performance. Derived from 37% renewable plant-based materials, Sorona® delivers a 22% increase in loft compared to traditional polyester and improves heat dissipation by 35%. This sustainable fiber also reduces carbon emissions by up to 30% during production. Additionally, the fitted sheet fabrics include 25% GRS-certified recycled PET, further supporting CozyBliss’s commitment to environmental responsibility.
The surface of each comforter boasts a Q-Max value greater than 0.4, enabling an instant cooling effect that can reduce body temperature by 2–5°C. Crafted with precision quilting in both feathered and diamond patterns, the bedding combines tactile cooling with elevated aesthetic appeal. The 3D woven textures not only improve airflow but also provide a sleek, contemporary look that complements modern interior styles.
Stylish, Skin-Friendly, and Safe
The COOLI PRO series is available in sophisticated dual-tone colorways, including Creamy White – Misty White and Meteor Grey – Cool Grey, making it a perfect match for minimalist and modern American home décor.
Every product in the COOLI PRO collection has been independently tested and certified to meet OEKO-TEX® Standard 100, the highest safety standard. This ensures they are free from 138 potentially harmful substances, making them safe for use by all, including infants and those with sensitive skin.
Purchase Information
COOLI Series
Lightweight summer blankets with 100% poly down-alternative filling create a 3D hollow structure for enhanced elasticity and durability. Designed for summer use with excellent abrasion resistance.
COOLI PRO Series
The upgraded COOLI PRO comforter features Sorona® filling with a helical fiber structure for enhanced breathability and support. The reversible design provides both versatility and modern style.
Website: https://www.cozybliss.com/products/lightweight-natural-cooling-comforter?variant=47795869122806
The full collection is available for purchase through the CozyBliss website and Amazon CozyBliss Store.
About CozyBliss
Founded with a vision to redefine modern comfort, CozyBliss is a leading brand in American home living. The company offers an all-season, all-scene product line designed to help consumers effortlessly switch into comfort mode anytime, anywhere. By combining thoughtful design, sustainable materials, and superior craftsmanship, CozyBliss brings lasting coziness to homes around the world.
Media Contact
Organization: CozyBliss
Contact
Person: Media Relations
Website:
https://www.cozybliss.com/
Email:
marketing@cozybliss.com
Country:United States
The post CozyBliss Introduces 2025 COOLI PRO Cooling Comforter Featuring Sorona Technology appeared first on
Brand News 24.
It is provided by a third-party content
provider. Brand News 24 makes no
warranties or representations in connection with it.
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
Press Release
Blue Sky Scrubs Celebrates World Environment Day with Commitment to Sustainability and Innovation
United States, 29th Apr 2025, – Austin, TX — As the world comes together to celebrate World Environment Day on June 5, Blue Sky Scrubs is proud to spotlight its ongoing commitment to protecting the planet through thoughtful, sustainable practices. The luxury medical apparel company, known for blending style with functionality, believes that caring for the environment is a natural extension of its mission to care for healthcare professionals.
In honor of World Environment Day on June 5, Blue Sky Scrubs is proud to reaffirm its commitment to protecting the planet through sustainable business practices. As a leader in luxury medical apparel, the company believes that caring for healthcare professionals also means caring for the environment they live and work in.
Blue Sky Scrubs focuses on creating long-lasting products by using premium fabrics and expert craftsmanship, helping reduce the fast-fashion waste cycle. By designing scrubs and accessories that withstand daily wear and maintain their quality over time, the company encourages a more sustainable approach to medical workwear.
In addition, Blue Sky Scrubs minimizes the use of plastic in packaging, supports local and ethical manufacturing, and donates surplus inventory to medical missions and nonprofits, ensuring that unused items serve communities in need rather than ending up in landfills.
“We are inspired every day by healthcare workers who protect and heal,” said Shelby Marquardt, founder of Blue Sky Scrubs. “Our mission is to create products that not only serve them but also help preserve the environment for future generations.”
This World Environment Day, Blue Sky Scrubs invites the healthcare community and its supporters to reflect on the small changes that, together, can make a big difference for the planet.
For more about Blue Sky Scrubs’ sustainability efforts, visit blueskyscrubs.com.
Media Contact
Organization: MFLP
Contact
Person: Suzy Aguilera
Website:
https://blueskyscrubs.com/
Email:
info@blueskyscrubs.com
Contact Number: 18883025837
Country:United States
The post Blue Sky Scrubs Celebrates World Environment Day with Commitment to Sustainability and Innovation appeared first on
Brand News 24.
It is provided by a third-party content
provider. Brand News 24 makes no
warranties or representations in connection with it.
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
GroundingTime Debuts Eco-Friendly Bamboo Grounding Sheet to Redefine Rest
CozyBliss Introduces 2025 COOLI PRO Cooling Comforter Featuring Sorona Technology
Blue Sky Scrubs Celebrates World Environment Day with Commitment to Sustainability and Innovation
Bay Smokes Maintains Quality Amid Legislative Changes in the Hemp Industry
Benzinga Money Article Discusses How to Become Part of the 12% of Retirees Who Have Achieved the Recommended $550,000 Minimum Retirement Savings Threshold
Apu Apustaja Conquers New York with Lively Street Ads, Including Times Square Billboard
-
Press Release5 days ago
The Illusion of Change — A Bold Philosophical Reflection by Adrian Gabriel Dumitru Challenges the True Nature of Transformation
-
Press Release1 week ago
Premium Resources Confirms High-Grade Copper-Nickel Zone in Botswana, Begins Resource Expansion.
-
Press Release5 days ago
Hybrid Collapse Releases Captivating New Album “Biopolitics”
-
Press Release4 days ago
Champion Window Tinting Announces Cutting-Edge Solutions for Energy Savings and Privacy Enhancement
-
Press Release4 days ago
Raven Keiara named Los Angeles finalist for 2025 August Wilson New Voices Monologue Competition
-
Press Release3 days ago
Cloom Tech Offers OEM Wire Harness Manufacturing Solutions
-
Press Release1 week ago
Sleep Dentistry Brisbane Introduces Safe Laughing Gas Sedation for Stress-Free Visits
-
Press Release6 days ago
MeFold Introduces Foldable, Sustainable Water Bottles to Support Eco-Friendly Lifestyles and On-the-Go Hydration