Press Release
CMS (867.HK/8A8.SG): Innovative Drug Oral JAK1 Inhibitor Povorcitinib Has Been Included in the List of Breakthrough Therapeutic Drugs in China
SHENZHEN, CHINA – China Medical System Holdings Limited (“CMS”, or the “Group”) is pleased to announce that its subsidiary, Dermavon Holdings Limited (“Dermavon”, an innovative pharmaceutical company specialized in skin health which is applying for an independent listing on the Main Board of The Stock Exchange of Hong Kong Limited, please refer to the announcement of the Company dated 22 April 2025 for details), has obtained the relevant licensing rights to the innovative oral JAK1 inhibitor povorcitinib (proposed English generic name: Povorcitinib Phosphate Tablets) (“povorcitinib” or the “Product”), which has been included in the list of Breakthrough Therapeutic Drugs by the Center for Drug Evaluation of the National Medical Products Administration of the People’s Republic of China (“NMPA”), with a proposed indication for adult patients with non-segmental vitiligo. This certification has the potential to accelerate the development and review process of the Product.
Povorcitinib is a selective oral small-molecule JAK1 inhibitor, with compound and use patents in certain countries/regions in the Territory. Currently, povorcitinib is in Phase 3 clinical trials for non-segmental vitiligo, moderate to severe hidradenitis suppurativa (HS) and prurigo nodularis in several countries outside China. A Phase 2 clinical trial for the treatment of asthma is also ongoing.
In March 2023, Incyte announced that povorcitinib met the primary endpoint in a global multi-center Phase 2b clinical trial for non-segmental vitiligo. Results showed that after 24 weeks of treatment, compared with vehicle, total body repigmentation of patients treated with povorcitinib once daily was significantly improved. Furthermore, according to the extended Phase 2b trial, longer-term use of povorcitinib demonstrated further improvement in total body and facial repigmentation with a favorable tolerability profile[1].
In August 2025, Dermavon received the drug clinical trial approval notice issued by NMPA to conduct clinical trials of povorcitinib for the treatment of non-segmental vitiligo and other indications. Dermavon has initiated the clinical development of the Product in China and may consider further initiating clinical development of povorcitinib in China for the treatment of skin-related diseases such as HS and prurigo nodularis in the future.
Vitiligo is a chronic autoimmune disease characterized by depigmentation of the skin, which results from the loss of pigment-producing cells known as melanocytes. It is estimated that there are approximately 10.3 million vitiligo patients in China and non-segmental vitiligo patients account for approximately 8.2 million[2]. Currently, therapeutic options for vitiligo are limited, and the condition is difficult to treat, especially for patients with moderate to severe extensive vitiligo. If approved in China, povorcitinib could provide a differentiated treatment option for patients with non-segmental vitiligo.
The Product’s inclusion in the list of Breakthrough Therapeutic Drugs is expected to accelerate its development and review process in mainland China. If approved for marketing in China, the Product has the potential to synergize with Dermavon’s commercialized innovative drug ILUMETRI (tildrakizumab injection), commercialized exclusive drug Hirudoid (mucopolysaccharide polysulfate cream) and the innovative drug currently under New Drug Application (NDA) review ruxolitinib phosphate cream, helping the product to quickly realize its clinical and commercial value and benefit more patients with skin diseases. Furthermore, if approved, the Product, together with topical ruxolitinib phosphate cream, will provide vitiligo patients with differentiated and comprehensive treatment options.
The Group, through a subsidiary of Dermavon entered into a Collaboration and License Agreement (the “License Agreement”) for povorcitinib on 31 March 2024 with Incyte, obtaining an exclusive license to research, develop, register and commercialize the Product in Mainland China, Hong Kong Special Administrative Region, Macao Special Administrative Region, Taiwan Region and eleven Southeast Asian countries (the “Territory”) and a non-exclusive license to manufacture the Product in the Territory. The subsidiary of Dermavon has sublicensed the relevant rights of povorcitinib in the Territory other than Mainland China to the Group (excluding Dermavon and its subsidiaries).
About CMS
CMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet medical needs.
CMS focuses on the global first-in-class (FIC) and best-in-class (BIC) innovative products, and efficiently promotes the clinical research, development and commercialization of innovative products, enabling the continuous transformation of scientific research into clinical practices to benefit patients.
CMS deeply engages in several specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to promote the in-depth development in its advantageous specialty fields, strengthening the competitiveness of the cardio-cerebrovascular/ gastroenterology/ ophthalmology/ skin health businesses, bringing economies of scale in specialty fields. Among them, the skin health business (Dermavon) has become a leading enterprise in its field, and is proposed to be listed independently on the SEHK. Meanwhile, CMS continuously promotes the operation and development of its integrated R&D, manufacturing and commercialization chain in Southeast Asia and the Middle East, capturing growth opportunities in emerging markets to support the high-quality and sustainable development of the Group.
Reference：
- Results from a global multi-center Phase 2b clinical trial of the product for non-segmental vitiligo indication can be found on the Incyte official website: https://investor.incyte.com/news-releases/news-release-details/incyte-an…
- Datas are from the China Insights Consultancy (CIC) report
CMS Disclaimer and Forward-Looking Statements
This press release is not intended to promote any products to you and is not for advertising purposes. This press release does not recommend any drugs, medical devices and/or indications. If you want to know more about the diagnosis and treatment of specific diseases, please follow the opinions or guidance of your doctor or other medical and health professionals. Any treatment-related decisions made by healthcare professionals should be based on the patient’s specific circumstances and in accordance with the drug package insert.
This press release which has been prepared by CMS does not constitute any offer or invitation to purchase or subscribe for any securities, and shall not form the basis for or be relied on in connection with any contract or binding commitment whatsoever. This press release has been prepared by CMS based on information and data which it considers reliable, but CMS makes no representation or warranty, express or implied, whatsoever, and no reliance shall be placed on, the truth, accuracy, completeness, fairness and reasonableness of the contents of this press release. Certain matters discussed in this press release may contain statements regarding the Group’s market opportunity and business prospects that are individually and collectively forward-looking statements. Such forward-looking statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties and assumptions that are difficult to predict. Any forward-looking statements and projections made by third parties included in this press release are not adopted by the Group and the Company is not responsible for such third-party statements and projections.
Media Contact
Brand: China Medical System Holdings Ltd.
Contact: CMS Investor Relations
Email: ir@cms.net.cn
Website: https://web.cms.net.cn/en/home/
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
Press Release
MARS Umzuge Enhances Europe-Wide Operations to Meet Growing Demand for International Relocation
In order to meet the increasing demand for international moving services and ease the customers’ experience of cross-border moves, MARS Umzuge has decided to extend its services throughout Europe. Berlin-based relocation company strengthens its operations across Europe to support smooth and reliable international moves.
Berlin, Germany, 21st Apr 2026 – MARS Umzuge, a relocation company based in Berlin has today announced a Europe expansion of its operations covering more countries to address increasing demands in international relocation services. The European region has been increasing mobility from country to country, necessitating an improved infrastructure, logistics coordination and service capability for maximum effectiveness, safety and customer-orientation in their relocation experiences.
Growing Demand for International Moving
In recent years a number of people and businesses are now moving between various European countries. This has created high demand for reliable removal services. MARS Umzuge, a trusted moving company in Berlin, has observed a steady increase in inquiries about international relocation services.
The company already offers structured and well-planned Removals Berlin services. With this expansion, it aims to improve its ability to handle moves across different countries in Europe. The goal is to make the moving process easier more predictable and less stressful for customers.
Focus on Better Planning and Coordination
The major areas to be addressed are logistics and coordination. MARS Umzuge Berlin is known for its full planning, proper handling of consignments and immediate services of deliveries.
International operations demand multi-layered coordination across borders with a central hub linking each participating site. To conduct all this firm has been enhancing its transport planning and route management. This ensures no more delays and assures the timely arrival of the goods, safely. The company reaches its peak status because the Removals Berlin service is carefully planned, ensuring every step is transparent for clients.
Simple and Transparent Moving Process
MARS Umzuge also worked to keep our services simple and easy to understand. Customers were guided throughout the entire moving process right from planning to packing, transportation and delivery. Being a Moving company Berlin has to focus on good communication skills with its clients, which helps prevent confusion and builds trust during the moving phase. Its Removals Berlin services are structured in a way that customers can stay informed and feel more confident about their relocation.
Flexible Services for Different Needs
MARS Umzuge perceives the diversity in each move as its solution to provide a wide range of services for every relocation. In Germany or throughout Europe, a move will always be treated with one and the same level of services. Being an adversity-resilient Moving company Berlin has carried MARS Umzuge seamlessly through the line with small and big moves. Combining the company’s resources has proven beneficial in consistently achieving the aim of assisting individuals, families and enterprises. Further expansions in its Removals Berlin services have given the company a way to handle any number of moving problems elsewhere in Europe.
Maintaining Quality and Reliability
Reliability and Quality, being the primary focus for MARS Umzuge, serve for practicality in all dealings. Their contract establishes a systematic strategy that emphasizes careful management and prompt delivery of products. As Berlin’s most dependable moving company demonstrates careful attention to essential tasks like packing, loading and transportation all of which are crucial for ensuring safety during the lengthy and challenging journey. The entire procedure is regularly reviewed to improve service standards ensuring that all goods and relocation services are provided through our trusted Removals Berlin network everywhere.
Future Plans
As international moves become more frequent, a foreign moving company might find it beneficial to further familiarize itself with the process, reflecting an ongoing industry trend. And recognizing this, the organized and reliant presence of an international moving company has its reason. And MARS Umzuge, the company puts in work towards enhancing operations, preparing to make moves easier for helpful clients. The moving company, gaining popularity in Berlin, is broadening its reach throughout Europe to promote seamless and efficient relocations. In Removals Berlin, simple processes and trustworthiness will undoubtedly remain the cornerstone.
About MARS Umzuge
MARS Umzuge is a Berlin-based moving company that undertakes moves on behalf of people and companies. They’ve always closed the sale off at the highest level of organizational skills service you can rely on and straightforward communication. They are the masters at providing a professional removals company Berlin facility to their clients to make moving precious stuff easy and efficient. Indeed MARS Umzuge gives world citizens help at moving quite around in Europe for internal and outside movers.
Media Contact
Website: https://www.mars-umzuege.de/
Email: info@mars-umzuege.de
Contact No: +49 30 12021901
WhatsApp: 0163 62 49 365
Waldstraße 71, 13403 Berlin, Germany
Media Contact
Organization: Mars Umzüge
Contact Person: Mars Umzüge
Website: https://www.mars-umzuege.de/
Email: Send Email
Contact Number: +493012021901
Address:Waldstraße 71, 13403
City: Berlin
Country:Germany
Release id:44193
The post MARS Umzuge Enhances Europe-Wide Operations to Meet Growing Demand for International Relocation appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
Press Release
MARS Umzuge Enhances Europe-Wide Operations to Meet Growing Demand for International Relocation
In order to meet the increasing demand for international moving services and ease the customers’ experience of cross-border moves, MARS Umzuge has decided to extend its services throughout Europe. Berlin-based relocation company strengthens its operations across Europe to support smooth and reliable international moves.
Berlin, Germany, 21st Apr 2026 – MARS Umzuge, a relocation company based in Berlin has today announced a Europe expansion of its operations covering more countries to address increasing demands in international relocation services. The European region has been increasing mobility from country to country, necessitating an improved infrastructure, logistics coordination and service capability for maximum effectiveness, safety and customer-orientation in their relocation experiences.
Growing Demand for International Moving
In recent years a number of people and businesses are now moving between various European countries. This has created high demand for reliable removal services. MARS Umzuge, a trusted moving company in Berlin, has observed a steady increase in inquiries about international relocation services.
The company already offers structured and well-planned Removals Berlin services. With this expansion, it aims to improve its ability to handle moves across different countries in Europe. The goal is to make the moving process easier more predictable and less stressful for customers.
Focus on Better Planning and Coordination
The major areas to be addressed are logistics and coordination. MARS Umzuge Berlin is known for its full planning, proper handling of consignments and immediate services of deliveries.
International operations demand multi-layered coordination across borders with a central hub linking each participating site. To conduct all this firm has been enhancing its transport planning and route management. This ensures no more delays and assures the timely arrival of the goods, safely. The company reaches its peak status because the Removals Berlin service is carefully planned, ensuring every step is transparent for clients.
Simple and Transparent Moving Process
MARS Umzuge also worked to keep our services simple and easy to understand. Customers were guided throughout the entire moving process right from planning to packing, transportation and delivery. Being a Moving company Berlin has to focus on good communication skills with its clients, which helps prevent confusion and builds trust during the moving phase. Its Removals Berlin services are structured in a way that customers can stay informed and feel more confident about their relocation.
Flexible Services for Different Needs
MARS Umzuge perceives the diversity in each move as its solution to provide a wide range of services for every relocation. In Germany or throughout Europe, a move will always be treated with one and the same level of services. Being an adversity-resilient Moving company Berlin has carried MARS Umzuge seamlessly through the line with small and big moves. Combining the company’s resources has proven beneficial in consistently achieving the aim of assisting individuals, families and enterprises. Further expansions in its Removals Berlin services have given the company a way to handle any number of moving problems elsewhere in Europe.
Maintaining Quality and Reliability
Reliability and Quality, being the primary focus for MARS Umzuge, serve for practicality in all dealings. Their contract establishes a systematic strategy that emphasizes careful management and prompt delivery of products. As Berlin’s most dependable moving company demonstrates careful attention to essential tasks like packing, loading and transportation all of which are crucial for ensuring safety during the lengthy and challenging journey. The entire procedure is regularly reviewed to improve service standards ensuring that all goods and relocation services are provided through our trusted Removals Berlin network everywhere.
Future Plans
As international moves become more frequent, a foreign moving company might find it beneficial to further familiarize itself with the process, reflecting an ongoing industry trend. And recognizing this, the organized and reliant presence of an international moving company has its reason. And MARS Umzuge, the company puts in work towards enhancing operations, preparing to make moves easier for helpful clients. The moving company, gaining popularity in Berlin, is broadening its reach throughout Europe to promote seamless and efficient relocations. In Removals Berlin, simple processes and trustworthiness will undoubtedly remain the cornerstone.
About MARS Umzuge
MARS Umzuge is a Berlin-based moving company that undertakes moves on behalf of people and companies. They’ve always closed the sale off at the highest level of organizational skills service you can rely on and straightforward communication. They are the masters at providing a professional removals company Berlin facility to their clients to make moving precious stuff easy and efficient. Indeed MARS Umzuge gives world citizens help at moving quite around in Europe for internal and outside movers.
Media Contact
Website: https://www.mars-umzuege.de/
Email: info@mars-umzuege.de
Contact No: +49 30 12021901
WhatsApp: 0163 62 49 365
Waldstraße 71, 13403 Berlin, Germany
Media Contact
Organization: Mars Umzüge
Contact Person: Mars Umzüge
Website: https://www.mars-umzuege.de/
Email: Send Email
Contact Number: +493012021901
Address:Waldstraße 71, 13403
City: Berlin
Country:Germany
Release id:44193
The post MARS Umzuge Enhances Europe-Wide Operations to Meet Growing Demand for International Relocation appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
Post Oak Group, recently named the Best Middle-Market Investment Bank in Texas, is expanding its cross-border M&A capabilities to meet this demand, reinforcing its position as a premier advisor to founders, shareholders, and institutional investors pursuing international transactions.
Houston, Texas, United States, 21st Apr 2026 – As middle-market companies increasingly look beyond U.S. borders for growth, strategic partnerships, and capital, the demand for investment banks equipped to navigate cross-border complexity has never been greater. Post Oak Group, recently named the Best Middle-Market Investment Bank in Texas, is expanding its cross-border M&A capabilities to meet this demand, reinforcing its position as a premier advisor to founders, shareholders, and institutional investors pursuing international transactions.
The firm’s cross-border platform is built to address the unique challenges of international dealmaking: differing regulatory frameworks, currency exposure, tax structuring, cultural nuances in negotiation, and the coordination of buyers, investors, and counsel across multiple jurisdictions. With a track record spanning 12 countries and more than $82 billion in completed transactions, Post Oak Group has developed an execution framework designed specifically for the middle market, one that delivers institutional-grade advisory without the bureaucracy and inefficiency often associated with larger global banks.
A Differentiated Approach to International Dealmaking
Middle-market companies pursuing cross-border transactions have historically faced a difficult choice: engage a bulge-bracket bank where their deal risks being deprioritized, or work with a regional advisor lacking true international reach. Post Oak Group was built to eliminate that tradeoff.
“Middle-market founders and shareholders deserve the same caliber of cross-border execution that larger companies receive from global banks,” said Alex Treistman, Managing Partner of the Capital Markets practice at Post Oak Group. “Our platform is designed to deliver that level of sophistication while maintaining the senior-led attention and agility that defines how we operate.”
The firm’s recognition as the Best Middle-Market Investment Bank in Texas reflects this differentiated positioning, a testament to the firm’s ability to combine institutional-grade execution with the responsiveness and customization that middle-market clients require.
Senior-Led Execution Across Every Engagement
A defining feature of Post Oak Group’s cross-border model is the direct involvement of senior bankers throughout the lifecycle of every transaction. The firm’s leadership team brings more than 250 years of combined experience across capital markets, mergers and acquisitions, and a wide range of industry specializations.
Rather than delegating execution to junior staff once a mandate is won, a common dynamic at larger institutions, Post Oak Group’s senior professionals remain deeply engaged from initial strategy through closing. This partner-led model is particularly critical in cross-border engagements, where judgment, relationships, and real-time decision-making often determine the outcome of a transaction.
Global Reach, Integrated Platform
Post Oak Group operates a fully integrated investment banking platform spanning capital markets and M&A advisory, with approximately 300 professionals across advisory, execution, research, operations, and support functions. This integration allows the firm to seamlessly coordinate capital raises, recapitalizations, and buy-side or sell-side M&A mandates across jurisdictions, a capability that is increasingly important as middle-market companies pursue hybrid transactions combining capital infusion with strategic partnership or acquisition.
The firm’s international reach spans North America, Europe, Australia, Latin America, and select markets in Asia, supported by long-standing relationships with institutional investors, family offices, strategic acquirers, and private equity sponsors across the globe.
Meeting a Growing Need in the Middle Market
Cross-border M&A activity in the middle market has accelerated meaningfully in recent years, driven by supply chain realignment, the globalization of founder-owned businesses, and increased appetite from international strategic acquirers and institutional investors for U.S.-based middle-market assets. Post Oak Group’s expansion of its cross-border capabilities is designed to meet this demand head-on.
About Post Oak Group
Post Oak Group is a leading middle-market investment bank headquartered in Houston, Texas, recently recognized as the Best Middle-Market Investment Bank in Texas. The firm operates a fully integrated platform spanning capital markets and M&A advisory, with a track record of more than $82 billion in transactions across 12 countries. Post Oak Group serves founders, shareholders, and institutional investors through senior-led, partner-driven engagements designed to deliver institutional-grade execution with boutique-level attention.
For more information, visit postoakgroup.co
Media Contact
Organization: Post Oak Group
Contact Person: Alexander Treistman
Website: https://www.postoakgroup.co/
Email:
info@postoakgroup.co
City: Houston
State: Texas
Country:United States
Release id:44181
The post Post Oak Group Strengthens Cross-Border M&A Capabilities for Middle-Market Clients appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
MARS Umzuge Enhances Europe-Wide Operations to Meet Growing Demand for International Relocation
MARS Umzuge Enhances Europe-Wide Operations to Meet Growing Demand for International Relocation
Post Oak Group Strengthens Cross-Border M&A Capabilities for Middle-Market Clients
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