Press Release
CoinW Debuts Shardeum Token (SHM) Globally, Backing the Next Wave of Layer-1 Innovation
CoinW officially listed Shardeum’s native token SHM on May 8, 2025, supporting the world’s first autoscaling Layer-1 blockchain. Shardeum’s unique dynamic state sharding and consensus mechanism enable scalable, secure, and low-cost transactions. With CoinW’s deep liquidity and global reach, SHM aims to drive widespread adoption and innovation in the Layer-1 ecosystem.
On May 8, 2025, CoinW, a globally leading cryptocurrency exchange, officially listed SHM, the native token of the world’s first autoscaling blockchain Shardeum. This move marks not only a strategic advancement in CoinW’s Layer1 ecosystem deployment but also underscores the platform’s core commitment to user-first principles—curating high-potential, technology-driven assets for global investors.
As a key player in the infrastructure layer of the crypto industry, CoinW continues to fulfill its mission of Discovering Value, Empowering the Future by offering all-round support—technical, traffic, and resource-based—to enable promising projects to leap from technical innovation to full ecosystem growth.
Breaking the Blockchain Trilemma: Shardeum’s Scalable, Decentralized Vision
Shardeum is led by Nischal Shetty, a pioneering figure in India’s crypto space. Since 2022, Shetty has focused on Shardeum—an attempt to deliver a “high-performance, low-cost, and decentralized” Layer1 blockchain to power Web3 at scale globally.
Most Layer 1 blockchains have struggled to balance the “blockchain trilemma” – decentralization, scalability, and security – often sacrificing one to optimize the others. Some chose speed at the cost of decentralization, while others prioritized security but couldn’t scale efficiently. Shardeum breaks this pattern.
Its unique dynamic state sharding architecture and built-in autoscaling allow the network to scale linearly with demand. As more users and transactions flow in, the network automatically adds more nodes to handle the load – without spiking gas fees or slowing down.
At the same time, it remains permissionless and decentralized, with all nodes participating in consensus. Shardeum is among the first L1s to scale sustainably without sacrificing any pillar of the blockchain trilemma.
A Balanced Breakthrough: Shardeum’s Four Pillars of Innovation
CoinW Research conducted a comprehensive evaluation of Shardeum across four dimensions: technological innovation, permissionless nature, developer focus, and tokenomics:
- Technical Breakthrough: Shardeum’s Autoscaling capability allows the network throughput (TPS) to grow as more nodes join the network while maintaining gas fees consistently as low as $0.01 even during network congestion. The network uses dynamic state sharding and proprietary Proof-of-Quorum Optimistic (PoQo), allowing the network to scale near-infinitely as more nodes join.
- Permissionless validator network: Shardeum’s testnet saw over 171,000 physically run validator nodes – the highest among Layer 1 testnets. The Mainnet genesis starts with 256 validators (2 shards). At a time when many L1s face centralization tradeoffs, Shardeum is showcasing what a truly permissionless validator network can look like without requiring any complex setup. Thanks to Shardeum’s lightweight validator requirements, the node setup process works with a single command, asking users a few basic questions before spinning up a fully synced validator in under a minute. This drastically lowers the technical and time barriers to participation – especially in emerging markets – while reinforcing network decentralization.
- Developer focus: Shardeum has launched with 60+ open-source repositories and over 32,000 stars on GitHub, Shardeum’s codebase is open and transparent. At launch, Shardeum supports popular explorer tools with seamless integrations with major EVM-supporting wallets, including MetaMask.
- Optimized Tokenomics:
a) Staking Rewards: Users can earn around 50% APY to start to help bootstrap network security.
b) Deflationary Gas Mechanism: A portion of SHM tokens is burned with each transaction, creating long-term scarcity.
c) Ecosystem Reserve: 22.44% of the total supply is allocated for developer incentives, released in phases to ensure sustainable growth.
CoinW’s Comprehensive Support: Accelerating Shardeum’s Global Ascent
As the first exchange to launch SHM globally, CoinW played a pivotal role far beyond trading infrastructure. From brand amplification and user acquisition to ecosystem expansion, CoinW provided multidimensional support to help Shardeum stand out in the fiercely competitive Layer1 race.
In the early stage of launch, CoinW established a deep liquidity pool for SHM, ensuring seamless trading with zero slippage. Leveraging its vast social media presence, KOL network, and global partnerships, CoinW rapidly amplified Shardeum’s reach across key markets in Asia, Europe, and the Middle East—generating strong brand resonance and grassroots community momentum.
Alongside its trading and marketing efforts, CoinW Research has also delivered critical strategic insights to support Shardeum’s long-term growth. Guided by a “tech-driven, ecosystem-synergistic” philosophy, the institute evaluated the project through lenses of technological potential, real-world applications, and regulatory viability. Shardeum’s EVM compatibility, ultra-low gas fees, and dynamic sharding design not only solve the scalability-security-decentralization trilemma but also make it a compelling platform for global developers.
By offering deep liquidity, global exposure, technical evaluation, and ecosystem integration, CoinW not only facilitates Shardeum’s global expansion but also reaffirms its own role as a frontrunner in Layer1 infrastructure enablement.
CoinW × Shardeum—A Resonant Start to Ecosystem Synergy
The successful listing of SHM on May 8 solidified the strategic alignment between CoinW and Shardeum and accelerated the latter’s global rollout. As the launch partner, CoinW enabled Shardeum’s leap from tech stack to market presence, while also claiming a vital stake in the Layer1 ecosystem build-out.
Shardeum is more than a product of technical evolution—it embodies the global crypto community’s aspiration for digital sovereignty. With dynamic sharding as its spear and EVM compatibility as its shield, this Layer1 chain could reshape the blockchain narrative for emerging markets.
Looking ahead, CoinW will continue leveraging its liquidity depth, global brand assets, and strategic research capabilities to support Shardeum’s expansion into more real-world use cases—fueling its rise as a defining Layer1 project in emerging economies.
About CoinW
Founded in 2017, CoinW has become a leading global cryptocurrency asset trading platform. With a global footprint spanning over 200 countries, CoinW’s services reach more than 220 million digital asset users, offering a one-stop gateway to a comprehensive suite of crypto services. The platform offers one-stop intelligent trading services, with a daily trading volume surpassing $20 billion and ranking 4th in CMC contracts. With over 10 million registered users, CoinW focuses on empowering wealth growth and blockchain innovation, continuously optimizing its product structure. Since 2022, CoinW has expanded its brand influence through international sports sponsorships and a partnership with football legend Andrea Pirlo. Committed to social responsibility, CoinW has donated supplies to orphanages in Africa and supported animal welfare initiatives in Taiwan. Looking ahead, CoinW aims to drive global financial inclusion, lead the cryptocurrency industry, and accelerate the adoption of blockchain technology and digital assets. To learn more about CoinW, you can visit the website, and follow CoinW’s X Account, and Telegram Group.
Media Contact
Organization: CoinW
Contact Person: Angelo Tan
Website: https://www.coinw.com/
Email: Send Email
City: Dubai
Country:United Arab Emirates
Release id:27539
The post CoinW Debuts Shardeum Token (SHM) Globally, Backing the Next Wave of Layer-1 Innovation appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
Press Release
Gastro Center of Maryland Expands Footprint, Bringing Expert Digestive Care to More Communities Across the DMV
Gastro Center of Maryland (GCM), one of the state’s largest GI practices, announces expansion to serve more patients across the DMV. With locations in Annapolis, Bethesda, Columbia, Gaithersburg, Olney, Riverdale, Silver Spring, Timonium, and White Marsh, GCM offers comprehensive digestive care including colonoscopies, endoscopies, and advanced treatments. State-of-the-art facilities feature onsite pathology and an IBD Infusion Center. Same-week and NextDay appointments available. Now welcoming new patients.
Silver Spring, Maryland, United States, 1st Dec 2025 – Gastro Center of Maryland (GCM), one of the largest and most respected gastroenterology practices in the state, recently announced its continued expansion with the addition of Silver Spring and Bethesda Location. This strategic growth reinforces the organization’s commitment to delivering expert, compassionate digestive care closer to home for patients throughout Maryland and the greater DMV region.
With this expansion, Gastro Center of Maryland now operates 9 locations across the state, including Annapolis, Bethesda, Columbia, Gaithersburg, Olney, Riverdale, Silver Spring, Timonium/Lutherville, and White Marsh. The practice’s growth comes in direct response to increasing demand for specialized gastroenterological services as digestive health conditions continue to rise nationwide.
“Our mission has always been to provide exceptional, patient-centered digestive care to every community we serve,” said Sarah, an employee. “This expansion allows us to bring our expertise, advanced technology, and compassionate approach to even more patients who deserve convenient access to world-class gastroenterology services.”
Gastro Center of Maryland specializes in diagnosing and treating a comprehensive range of digestive and liver conditions, including acid reflux, irritable bowel syndrome (IBS), Crohn’s disease, ulcerative colitis, hepatitis, fatty liver disease, and colon cancer. The practice operates state-of-the-art Ambulatory Surgery Centers equipped with the latest medical technology, offering advanced procedures such as Bravo pH testing, PillCam capsule endoscopy, STRETTA for reflux treatment, and the Orbera gastric balloon system for weight loss.
Patients benefit from GCM’s integrated care model, which includes onsite pathology services and an IBD Infusion Center for faster, more accurate diagnoses and treatments. The practice also offers same-week and NextDay GI appointments, ensuring patients receive timely care when they need it most.
Gastro Center of Maryland accepts most major insurance plans, including private insurance, federally sponsored plans, and covered Maryland plans. New patients are welcome and can schedule appointments by calling (410) 290-6677 or visiting www.gastromaryland.com.
Media Contact
Organization: Gastro Center of Maryland
Contact Person: Daniel Dent
Website: https://www.gastromaryland.com/
Email:
christiang@gastrocenter.com
Contact Number: +14102906677
Address:10301 Georgia Ave #208
City: Silver Spring
State: Maryland
Country:United States
Release id:38186
The post Gastro Center of Maryland Expands Footprint, Bringing Expert Digestive Care to More Communities Across the DMV appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
Press Release
New Digital Philanthropy Initiative Launched at Asia Philanthropy Forum in Boao
In a significant move to harness technology for social good, the ECI@Charity Digital Philanthropy Innovation Committee was officially launched today at the Asia Philanthropy Forum in Boao. The establishment of this global platform marks a strategic evolution for ECI, positioning it from an innovation observer to a proactive builder in the philanthropic sector, leveraging the unique opportunities presented by the Hainan Free Trade Port.
Under the theme “Open Collaboration, Innovative Development,” the Forum gathered over 600 delegates from 16 countries and regions, including government officials, heads of international organizations, philanthropists, and leading entrepreneurs. The event was organized by the Hainan Asia Philanthropy Research Institute under the guidance of the China NGO Network for International Exchanges.
A First-of-its-Kind Global Platform
The ECI@Charity Committee stands as the world’s first cross-border platform dedicated to channeling digital innovation toward improving the lives and well-being of persons with disabilities. Its mission is to foster a more inclusive and caring digital society, enabling individuals with disabilities to achieve greater health, happiness, and dignity through technological empowerment.

Dr. Owen Jia, Global Initiator of ECI, addressed the Asian Philanthropy Forum on “ Powering Good with Digital, Reshaping Giving with Innovation “.
“We are bringing technological innovation back to its humanistic roots,” said Dr. Owen Jia, Global Initiator of the ECI Awards. “By focusing on fundamental human needs, we embark on a new journey of ‘Innovation for Good.’ This committee represents a concrete step toward our vision of serving as a ‘Nobel Prize for the innovation field.’”

Dr. Owen Jia (left), Global Initiator of ECI Awards, and Mr. Shouzhen Xu (right), Co-Chairman of Asian Philanthropy Forum and Executive Chairman of ECI@Charity.
To lead this initiative, Dr. Jia has appointed Mr. Xu Shouzhen as the Executive Chairman of ECI@Charity. Mr. Xu, who also serves as Co-Chairman of the Boao Forum for Asian Philanthropy, will spearhead efforts to consolidate top-tier global innovation resources. “Our goal is to build a transformative collaboration platform that delivers practical, tech-driven solutions in areas like digital healthcare and accessible entertainment,” stated Mr. Xu.
Four-Pillar Action Framework
The Committee will drive impact through four core initiatives:
1. Research & Insights: Publishing an annual “White Paper on Digital Life Needs and Technological Innovation for Persons with Disabilities.”
2. Connection & Co-creation: Hosting the “ECI@Charity Tech for Good Innovation Summit” and “Tech for Disability Innovation Marathon.”
3. Catalyzation & Implementation: Establishing an “ECI@Charity Seed Fund” and a curated “Solutions Resource Library.”
4. Recognition & Promotion: Integrating the specialized “ECI@Charity Awards” into the esteemed ECI Awards framework to benchmark excellence.
First Wave of Initiative Projects Launched
Concurrently, the Committee launched three initiative projects: the “Digital Healing” Partnership Program, connecting digital health enterprises with rehabilitation institutions; the “Accessible Gaming” Developers Alliance, formulating and promoting accessible game design standards; and the “Heartvoice Connect” Public Welfare Communication project, utilizing digital technologies to showcase the talents of artists with disabilities.
Launch Projects and Strategic Support
The Committee announced three flagship partnership programs at launch:
· The “Digital Healing” Partnership Program, linking digital health enterprises with rehabilitation institutions.
· The “Accessible Gaming” Developers Alliance, to formulate and promote inclusive game design standards.
· The “Heartvoice Connect” Public Welfare Communication project, using digital tools to amplify the talents of artists with disabilities.

Mr. James George, Deputy Resident Representative of the United Nations Development Programme (UNDP) in China, delivered a speech at the opening ceremony of the Asian Philanthropy Forum.
The initiative received notable support from the international community. Mr. James George, Deputy Resident Representative of the United Nations Development Programme (UNDP) in China, addressed the Forum, underscoring the importance of multi-stakeholder partnerships in achieving sustainable development goals.

2025 Asian Philanthropy Forum
Looking Ahead
Positioned at the new frontier of digital civilization, ECI@Charity will utilize the open policy framework of the Hainan Free Trade Port to aggregate global innovators. It aims to contribute substantively to a more equitable, inclusive, and compassionate digital future, solidifying its transition from an innovation observer to a definitive leader in shaping that future.
About ECI Awards
The ECI Awards (International Awards for Innovation in Business and Marketing), organized by the International Entrepreneurs, Creatives & Innovators Association (IECIA), is a globally recognized accolade celebrating innovation that creates new market value. It honors achievements across business models, products, services, technology, marketing, and social innovation.
Media Contact
Organization: Secretary General of EClAwards Committee
Contact Person: Faye Feng
Website: https://www.eciawards.org.cn
Email: Send Email
City: BOAO
Country:China
Release id:38261
The post New Digital Philanthropy Initiative Launched at Asia Philanthropy Forum in Boao appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
Press Release
Santersus AG Completes Series A Financing and Announces Strategic Collaboration with Terumo Corporation
Santersus AG Announces Advancement of NucleoCapture into Pivotal Clinical Development strengthened by Strategic Collaboration with Terumo
Zurich, Switzerland, 1st Dec 2025 – Santersus AG today announced the successful completion of its Series A financing, led by Norcliffe, a UK life sciences fund with participation from Terumo Ventures. The financing will support the advancement of Santersus’ NucleoCapture into pivotal clinical development while accelerating progress across Santersus’ broader pipeline.
Santersus has entered a strategic collaboration with Terumo Blood and Cell Technologies to advance NucleoCapture(TM) for the treatment of sepsis, a disease that kills 11M people worldwide each year. The collaboration integrates Santersus’ first-in-class NucleoCapture blood purification device with Terumo BCT’s industry-leading Spectra Optia Apheresis System, creating a novel therapeutic apheresis approach designed to selectively remove neutrophil extracellular traps (NETs)— a major contributor to systemic inflammation and sepsis-related organ dysfunction. NucleoCapture has previously been granted two U.S. FDA Breakthrough Device Designations, including one for the treatment of sepsis.
Under this collaboration, Santersus will lead the pivotal NUC-CAP clinical trial across the United States, United Kingdom, Switzerland and Europe. Terumo BCT will support the clinical development of the program, and Terumo Ventures – the corporate VC arm of Terumo – has invested in Santersus’ Series A financing round to accelerate the development of this technology for a critical unmet need with high mortality.
“Therapeutic apheresis has untapped potential to address serious unmet medical needs,” said Veerle d’Haenens, General Manager of Global Therapy Innovations at Terumo Blood and Cell Technologies. “Our partnership with Santersus reflects our commitment to advancing innovative treatment options for critically ill patients.”
The Series A financing will also support Santersus’ preparation for pivotal clinical trials in systemic lupus erythematosus (SLE), where NucleoCapture has received its second U.S. FDA Breakthrough Device Designation for treatment-refractory disease. The pivotal SLE program addressing an estimated $4bn global treatment market – will expand Santersus’ late-stage clinical portfolio beyond critical care and is expected to begin following the sepsis study launch.
Santersus is also advancing NucleoCapture technology into solid-organ transplantation, including a program designed to perfuse and recondition heavily damaged donor livers prior to transplantation. The global organ transplantation market is projected to reach $61.5bn by 2027. In parallel, Santersus is expanding a NucleoCapture program in lung transplantation focused on the prevention of primary graft dysfunction (PGD). Together, these initiatives support the application of NucleoCapture across solid-organ transplantation.
Santersus is also advancing early-stage development of NucleoCapture for Alzheimer’s disease, with an exploratory clinical study under way to assess its effects on amyloid removal. The global Alzheimer’s therapeutics market is valued at approximately $5bn in 2025 and is projected to double over the next decade.
These integrated programs reflect Santersus’ transition towards a multi-indication, late-stage clinical development company and position Santersus as a leading developer of NETs-targeted therapeutic apheresis technologies across critical care, autoimmunity, solid-organ transplantation, and neurodegeneration.
About Santersus AG
Zurich-based Santersus AG is a biotechnology company developing NucleoCapture, a novel, patent-protected extracorporeal blood purification technology designed to selectively remove cell-free DNA (cfDNA) and neutrophil extracellular traps (NETs). NucleoCapture has received two U.S. FDA Breakthrough Device Designations: one for the treatment of sepsis and one for systemic lupus erythematosus. Santersus is advancing a diversified clinical pipeline across sepsis, systemic lupus erythematosus, solid-organ transplantation (liver and lung), and Alzheimer’s disease.
For more information, please visit www.santersus.com
Media Contact
Organization: Santersus AG
Contact Person: Aleksander Zaporoztsev
Website: https://www.santersus.com
Email:
info@santersus.com
Country:Switzerland
Release id:38172
The post Santersus AG Completes Series A Financing and Announces Strategic Collaboration with Terumo Corporation appeared first on King Newswire. This content is provided by a third-party source.. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release. If you have any complaints or copyright concerns related to this article, please contact the company listed in the ‘Media Contact’ section
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
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