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China Medical System: First Prescriptions for Innovative Drug Lumeblue® Issued in China

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5 months ago

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SHENZHEN, CHINA – On 6 December, China Medical System Holdings Limited (“CMS” or the “Group”) is pleased to announce that the first prescriptions for the innovative drug Lumeblue® (Methylthioninium Chloride Enteric-coated Sustained-release Tablets) (the “Product”) have been issued in China, which marks that the first oral methylthioninium chloride enteric-coated sustained-release tablets in China has officially entered clinical application. The Product is indicated for enhancing visualization of colorectal lesions in adult patients undergoing screening or surveillance colonoscopies.

 

Lumeblue® is an oral diagnostic drug that uses patented multi-matrix (MMXTM) technology to deliver active substances directly to the colon and release them locally in a controlled manner. As an enhancer dye, the Product increases the contrast between colorectal lesions and healthy mucosa. The results of the Phase III clinical trial in China show that the Product can significantly improve the detection rate of non-polypoid colorectal lesions (the primary endpoint of the study), leading to an improved detection rate of dangerous lesions such as non-polypoid adenomas (the secondary endpoint)[1]. In addition, the Product can be taken during the bowel preparation step, ensuring that colorectal staining is completed by the time colonoscopy is conducted. This not only enhances the detection rate of colorectal lesions but also potentially simplifies the colonoscopy procedure, making the examination more efficient and improving the screening benefits.

 

According to the diagnosis and treatment data of the Digestive Endoscopy Branch of the Chinese Medical Association, approximately a total of 28 million gastroenteroscopies were completed nationwide in 2012, including 5.83 million colonoscopies. In 2019, approximately 38.73 million gastroenteroscopies were completed nationwide, an increase of 34.62% compared with 2012[2]. The Expert consensus on the early diagnosis and treatment of colorectal cancer in China (2023 edition) recommends colorectal cancer screening for individuals aged 40 to 74[3]. Based on the China Statistical Yearbook (2023), the total population of this age group in China is 643.36 million[4]. With the popularization of early colorectal cancer screening in China, the number of colonoscopies performed is expected to have significant growth potential in the future. Early diagnosis and removal of lesions are crucial for prevention. Lumeblue® provides an innovative solution for colorectal disease screening and management in response to this growing demand.

 

The Product has been approved by the European Medicines Agency (EMA) to be commercialized in the European Union under the trade name Lumeblue® in August 2020. The Group obtained an exclusive license for the Product from Cosmo Technologies Ltd., a fully-owned subsidiary of Cosmo Pharmaceuticals NV, on 3 December 2020. Following its approval in China in June 2024, CMS worked collaboratively across its business segments to ensure the rapid importation of the first batch of products. The Group has also actively leveraged its existing gastroenterology portfolio and resources to orderly advance the commercialization and academic promotion of Lumeblue®, facilitating its successful prescriptions launch in China.

 

With this milestone, CMS’s five innovative drugs have been successfully approved in China and fully entered clinical application. This achievement demonstrates the Group’s ongoing capability of innovation transformation, while reflecting CMS’s commitment to focusing on medical value and fulfilling its corporate social responsibility. Looking ahead, CMS will continue to be patients-centered, efficiently advancing the clinical development and commercialization of innovative products. The Group is dedicated to improving the accessibility and affordability of innovative drugs, benefiting a broader patient population.

 

About CMS

CMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet medical needs.

 

CMS focuses on the global first-in-class (FIC) and best-in-class (BIC) innovative products, and efficiently promotes the clinical research, development and commercialization of innovative products, enabling the continuous transformation of scientific research into clinical practices to benefit patients.

 

CMS deeply engages in several specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to promote the in-depth development of its advantageous specialty fields and expand business boundaries. While strengthening the competitiveness of the cardio-cerebrovascular/gastroenterology business, CMS independently operates its dermatology and medical aesthetics business, and ophthalmology business, aiming to gain leading positions in specialty therapeutic fields, whilst enhancing the scale and efficiency. At the same time, CMS has expanded its business territory to the Southeast Asian market, striving to become a “bridgehead” for global pharmaceutical companies to enter the Southeast Asian market, further escorting the sustainable and healthy development of the Group.

 

References:

CMS Disclaimer and Forward-Looking Statements

This press release is not intended to promote any products to you and is not for advertising purposes. This press release does not recommend any drugs, medical devices and/or indications. If you want to know more about the diagnosis and treatment of specific diseases, please follow the opinions or guidance of your doctor or other medical and health professionals. Any treatment-related decisions made by healthcare professionals should be based on the patient’s specific circumstances and in accordance with the drug package insert.

 

This press release which has been prepared by CMS does not constitute any offer or invitation to purchase or subscribe for any securities, and shall not form the basis for or be relied on in connection with any contract or binding commitment whatsoever. This press release has been prepared by CMS based on information and data which it considers reliable, but CMS makes no representation or warranty, express or implied, whatsoever, and no reliance shall be placed on, the truth, accuracy, completeness, fairness and reasonableness of the contents of this press release. Certain matters discussed in this press release may contain statements regarding the Group’s market opportunity and business prospects that are individually and collectively forward-looking statements. Such forward-looking statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties and assumptions that are difficult to predict. Any forward-looking statements and projections made by third parties included in this press release are not adopted by the Group and the Company is not responsible for such third-party statements and projections.

 

 

Media Contact

Brand: China Medical System Holdings Ltd.

Contact: CMS Investor Relations

Email: ir@cms.net.cn

Website: https://web.cms.net.cn/en/home/

Source: China Medical System Holdings Ltd.

 

  1. The results of the Product’s Phase III clinical trial in China were published and are available at: https://web.cms.net.cn/en/2022/12/positive-results-for-china-phase-iii-c…
  2. Data from the Digestive Endoscopy Branch of the Chinese Medical Association
  3. Early Diagnosis and Treatment Group of the Chinese Society of Oncology. “Expert Consensus on Early Diagnosis and Treatment of Colorectal Cancer in China (2023 Edition).” Chinese Medical Journal, 2023, 103(48): 3896-3908. DOI: 10.3760/cma.j.cn112137-20230804-00164
  4. National Bureau of Statistics. (2023). China Statistical Yearbook 2023. Retrieved from https://www.stats.gov.cn/sj/ndsj/2023/indexch.htm

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Press Release

Dubai-based IT-company Reputation House Won American Business Awards 2025

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2 hours ago

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April 30, 2025

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IT-company Reputation House is the only one company from Dubai to be recognized as the winner this year

United Arab Emirates, 30th Apr 2025, – Reputation House, an IT-company based in Dubai, has been announced a winner at the American Business Awards (The Stevie® Awards) for its IT solutions in online reputation management. The company was recognized as a Gold Winner in two categories: Innovation of the Year (Business Services Industries) and Most Innovative Tech Company of the Year (Up to 100 Employees). Additionally, Reputation House received the Bronze Stevie® Award for Best Data Tools & Platforms.

Dubai-based IT-company Reputation House Won American Business Awards 2025

This marks the second consecutive year the U.S. business community has honored Reputation House; the company captured one Gold and one Silver Stevie in 2024.

“Our 2025 tech expansion is about turning a once-traditional agency into a product-first software company,” said Dima Raketa, CEO of Reputation House. “Winning two Gold Stevies at America’s most respected business awards tells us we’re on the right path: our ecosystem of four interconnected tools will be redefining how global brands protect and grow their reputations. And we are just getting started.”

Kristina Shinkareva, COO, added: “This recognition belongs to our entire team — engineers and developers, data analysts, customer specialists, and every talent of Reputation House — whose hard work has turned big ideas into practical solutions that companies rely on every day.”

This year, Reputation House launched a full-scale technological transformation, unveiling four top-tier solutions that put complete online reputation control in clients’ hands. The new ecosystem starts with Reputation House Scan, which monitors mentions in 20+ languages, grades sentiment, and alerts teams to risks in real time. Account Control Center lets brands safely ignite and guide conversations across forums and social media, while the upgraded Reputation Check delivers fast, high-accuracy background reports on any partner, employee, or client. Rounding out the suite, the SERM Platform boosts search-engine rankings and surfaces positive content to the top of results pages. 

Together, these tools mark Reputation House’s shift from a traditional agency to a product-driven tech company—and set a new standard for how businesses protect and grow their digital presence.

To learn more about Reputation House, visit: www.reputation.house

Media Contact

Organization: Reputation House

Contact
Person: Media Relations

Website:

https://www.reputation.house/

Email:

pr@reputation.house

Country:United Arab Emirates

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Under the patronage of Maktoum bin Mohammed DIFC to host 3rd edition of Dubai FinTech Summit on 12 and 13 May 2025

Published

4 hours ago

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April 30, 2025

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  • His Highness: Summit reflects Mohammed bin Rashid’s vision of establishing Dubai as a global financial powerhouse
  • Summit to draw over 8,000 attendees and 300 speakers from more than 100 countries, and over 1,000 investors alongside top decision makers, thought leaders and experts
  • Essa Kazim: Through the summit, DIFC continues to showcase the tremendous opportunities for AI, FinTech and innovation companies in Dubai
  • Future Sustainability Forum will be incorporated into the summit for the first time
  • FinTech World Cup gives start-ups a platform to display solutions to investors, venture capitalists, and strategic partners

Dubai, UAE, 30th April 2025, ZEX PR WIRE, “The Dubai FinTech Summit reflects the vision of His Highness Sheikh Mohammed bin Rashid Al Maktoum, Vice President and Prime Minister of the UAE and Ruler of Dubai, of establishing Dubai as a global financial powerhouse. The Summit is set to attract over 8,000 attendees and 300 speakers from more than 100 countries, as well as over 1,000 investors alongside top decision makers, thought leaders and experts. This reflects Dubai’s pivotal role in shaping the future of finance globally, while reinforcing its status as the destination of choice for businesses and entrepreneurs worldwide. We are committed to supporting FinTech in line with the goal of the Dubai Economic Agenda D33 to position Dubai as a top four global financial centre by 2033.”

– His Highness Sheikh Maktoum bin Mohammed bin Rashid Al Maktoum, First Deputy Ruler of Dubai, Deputy Prime Minister, Minister of Finance, and President of DIFC

Government of Dubai Media Office – 13 April 2025: The Dubai International Financial Centre (DIFC) is set to host the third edition of the Dubai FinTech Summit on 12 and 13 May 2025, at the Madinat Jumeirah, Dubai, under the theme ‘FinTech for All’. The Summit, held under the patronage of His Highness Sheikh Maktoum bin Mohammed bin Rashid Al Maktoum, First Deputy Ruler of Dubai, Deputy Prime Minister, Minister of Finance, and President of DIFC, will bring together global industry leaders, innovators, and policymakers to explore the latest trends and insights driving the FinTech sector.

His Highness Sheikh Maktoum bin Mohammed said: “The Dubai FinTech Summit reflects the vision of His Highness Sheikh Mohammed bin Rashid Al Maktoum, Vice President and Prime Minister of the UAE and Ruler of Dubai, of establishing Dubai as a global financial powerhouse. The Summit is set to attract over 8,000 attendees and 300 speakers from more than 100 countries, as well as over 1,000 investors alongside top decision makers, thought leaders and experts. This reflects Dubai’s pivotal role in shaping the future of finance globally, while reinforcing its status as the destination of choice for businesses and entrepreneurs worldwide. We are committed to supporting FinTech in line with the goal of the Dubai Economic Agenda D33 to position Dubai as a top four global financial centre by 2033.”

Drivers of FinTech growth

The FinTech sector continues to grow and by 2030 global revenues are expected to reach $1.5 trillion, representing an estimated 7% of the total financial services market. This growth is driven by advancements in artificial intelligence, blockchain and digital banking, creating new opportunities for financial institutions and technology companies worldwide.

Dubai FinTech Summit is at the heart of these developments. Its agenda will address the future of finance, financial innovation and regulatory compliance, while highlighting the challenges and opportunities the sector presents. It will also cover the latest in key areas such as blockchain technology, AI-driven services, and digital banking. Furthermore, the summit will explore investment trends, global economic shifts, and cross-border regulations.

Attracting talent

His Excellency Essa Kazim, Governor of DIFC said: “Through the Dubai FinTech Summit, DIFC continues to showcase the tremendous opportunities AI, FinTech and innovation companies can access when they establish in Dubai. As we relentlessly foster an environment of innovation and excellence, we are solidifying Dubai’s position as one of the world’s foremost destinations for FinTech talent and investment.”

Accompanying exhibition and Future Sustainability Forum

Providing a global platform for innovation, building partnerships and driving the next wave of FinTech advancements, the Summit will also feature an exhibition with 200 exhibitors.

The Future Sustainability Forum will be incorporated into the Dubai FinTech Summit for the first time, and the alignment is reflected in the Summit’s theme of ‘FinTech for All’. Associated sessions will highlight accessibility, inclusivity and empowerment in the financial sector.

Key speakers

Amongst the distinguished lineup of speakers are His Excellency Marko Primorac, Deputy Prime Minister and Minister of Finance of Croatia; His Excellency Gilles Roth, Minister of Finance, Luxembourg; Timothy Adams, President and Chief Executive Officer, Institute of International Finance (IIF), USA; Tony O Elumelu, Chairman of United Bank for Africa and Founder of Tony Elumelu Foundation, Nigeria; and Vijay Shekhar Sharma, Founder & Chief Executive Officer, Paytm, India.

The Summit will feature start-up and country pavilions in the exhibition arena to showcase cutting-edge solutions from emerging and established players. Additionally, the FinTech World Cup will give promising FinTech start-ups a global platform to display their solutions to investors, venture capitalists, and strategic partners, and an opportunity for investors to find the next big idea.

Reflecting the continued importance of FinTech to the finance industry, the event is being supported by Emirates NBD as Premium Banking Partner, Commercial Bank of Dubai as Strategic Banking Partner; Relm Insurance as Strategic Partner; Presight as AI Industry Leader; Pay10 and Alibaba Cloud as Platinum Sponsors; Seoul FinTech Lab as a Pavillion Partner; and Business Sweden as the Country Partner.

Registrations for Dubai FinTech Summit are now open at dubaifintechsummit.com.

About Dubai FinTech Summit

Dubai FinTech Summit is an annual mega event organised by the Dubai International Financial Centre (DIFC), the leading global financial centre in the Middle East, Africa and South Asia (MEASA) region. The 3rd edition of the Dubai FinTech Summit will bring together over 8,000+ global industry leaders, 1,000+ investors and policy makers, signalling increased appetite for growth opportunities in the region.

Dubai FinTech Summit signals new wave of financial innovation, opportunity, transformation, and growth for the international financial services sector.  As a rising FinTech hub, Dubai is also spearheading the evolution of the financial services industry, with investments in FinTech projected to grow by 17.2 per cent CAGR to USD949 bn from 2022 to 2030. The Summit aligns with the Dubai Economic Agenda D33’s strategic goal of propelling Dubai into the ranks of the top four global financial hubs by 2033.

The expanded programme of Dubai FinTech Summit is set to exceed expectations by delving into key tracks, including the future of FinTech, global economic trends, blockchain and cryptocurrency, regulatory compliance, and investment outlook. The summit stands as a thought leadership-driven platform, addressing industry challenges head-on and championing innovation.

For more information, contact:

Shadi Dawi

Sr. Director – PR, Comms., & Media

M: +971 55 498 4989 | E: shadi@tresconglobal.com

Media partners include:

Entrepreneur ME –  Ecosystem Partner

Arabian Business –  Business Media Partner

The FinTech Times – Newspaper Partner

Finance World Magazine –  Finance Magazine Partner

The Technology Express –  Technology Intelligence Partner

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Press Release

Safetyvalue Trading Center Launches Mobile App V2 With Biometric Login and Real-Time Alerts

Published

9 hours ago

on

April 30, 2025

By

Safetyvalue Trading Center unveils Mobile App V2, featuring biometric authentication, customizable dashboards, and push notifications to support secure, high-speed crypto trading for users around the world.

Safetyvalue Trading Center today announced the official release of Safetyvalue Mobile App V2, a major update to its iOS and Android applications that brings powerful new features, optimized performance, and improved accessibility for global cryptocurrency traders. This latest version reflects the company’s focus on delivering a streamlined, user-friendly mobile experience without compromising on security or functionality.

Safetyvalue Trading Center Launches Mobile App V2 With Biometric Login and Real-Time Alerts

The V2 upgrade introduces a redesigned interface that makes it easier for users to view markets, manage portfolios, and execute trades in just a few taps. In addition to the sleek new design, Safetyvalue has integrated biometric login options, including Face ID and fingerprint authentication, for enhanced account security and convenience.

Key upgrades include:

Biometric authentication for secure, password-free access

Customizable trading dashboard with real-time charts, order book, and price alerts

Push notifications for price movements, order execution, and system updates

NFT wallet view and direct marketplace access

One-click switching between spot, margin, and DeFi modes

Support for 10+ languages, including Spanish, Arabic, Japanese, and Portuguese

“The mobile experience is critical to modern crypto users, and V2 is designed to meet their evolving needs,” said a Safetyvalue product director. “Whether users are tracking NFT auctions, managing a diverse portfolio, or executing high-frequency trades, the new app ensures everything is accessible, fast, and secure—right from their pocket.”

The new app architecture has also been optimized for low-bandwidth environments and faster load times, especially in emerging markets. Safetyvalue has implemented advanced caching and real-time syncing mechanisms that allow users to stay connected even with intermittent internet access.

In addition to core trading features, Safetyvalue App V2 includes educational modules, how-to guides, and integrated customer support via live chat and help center browsing. This makes it easier for new users to onboard and begin trading with confidence, regardless of prior experience.

The updated mobile app plays a key role in Safetyvalue’s broader mission to provide borderless, 24/7 access to digital assets. It supports all Safetyvalue account types and integrates seamlessly with the platform’s unified multi-asset system, allowing users to manage fiat, crypto, NFTs, and DeFi positions from a single wallet interface.

App V2 is now available on the Apple App Store and Google Play, with rollout support for over 100 countries. Safetyvalue has confirmed that additional features—such as wallet connect integrations, staking dashboards, and multi-account switching—are in development for upcoming releases.

Download or learn more at:

https://safetyvalue.info

https://safetyvalue-review.com

https://safetyvaluetrading.center

https://safetyvaluetrading.pro

https://safetyvalue.wiki

Media Contact

Organization: Safetyvalue

Contact Person: Alexander Griffin

Website: https://safetyvalue.com/

Email: Send Email

Country:United States

Release id:27142

Disclaimer: The information provided in this press release is for informational purposes only and does not constitute investment advice, financial advice, trading advice, or any other sort of advice. Safetyvalue Trading Center does not recommend that any cryptocurrency should be bought, sold, or held by you. Conduct your own due diligence and consult your financial advisor before making any investment decisions. Cryptocurrency trading involves substantial risk and may not be suitable for all investors.

View source version on King Newswire:
Safetyvalue Trading Center Launches Mobile App V2 With Biometric Login and Real-Time Alerts

It is provided by a third-party content provider. King Newswire makes no warranties or representations in connection with it. King Newswire is a press release distribution agency and does not endorse or verify the claims made in this release.

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