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Tonix Pharmaceuticals releases positive results from Proof-Of-Concept Study on TNX-102 SL

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–News Direct–

Tonix Pharmaceuticals CEO Dr Seth Lederman joined Steve Darling from Proactive to share significant news regarding the Phase 2 proof-of-concept PREVAIL study of TNX-102 SL 5.6 mg for the management of fibromyalgia-type Long COVID. Dr Lederman provided an overview of the study's topline results and the implications for future development.

Dr Lederman announced that the study showed a robust effect size in improving fatigue, a key symptom of Long COVID. The results also demonstrated consistent activity trending towards improvements across secondary endpoints, including sleep quality, cognitive function, disability, and patient global impression of change. However, Dr Lederman noted that TNX-102 SL did not achieve the pre-specified primary endpoint of improving Long COVID pain intensity scores at Week 14.

Despite this, the proposed mechanism of TNX-102 SL, which aims to improve sleep quality, aligns with recent announcements from the National Institutes of Health (NIH) that sleep quality is a target for future clinical trials in Long COVID.

Dr Lederman highlighted that there is currently no approved drug for the treatment of Long COVID, making these findings important for potential future treatments. The company's plan is to request an End-of-Phase 2 meeting with the U.S. Food and Drug Administration (FDA) to discuss the possibility of a Phase 3 program. They intend to propose a primary outcome measure using the PROMIS Fatigue scale, which is widely recognized and validated for assessing fatigue across various conditions.

Dr Lederman also told Proactive the company is committed to meeting potential increased demand for its Tosymra nasal spray 10 mg following GlaxoSmithKlines planned discontinuation of Imitrex nasal spray 5 mg and 20 mg products after January 2024.

This move by Tonix is to be ready in case of possible drug shortages for patients who suffer from migraines.

Contact Details

Proactive Studio

+1 347-449-0879

[email protected]

View source version on newsdirect.com: https://newsdirect.com/news/tonix-pharmaceuticals-releases-positive-results-from-proof-of-concept-study-on-tnx-102-sl-959108196

Tonix Pharmaceuticals

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News Direct Hires Respected Industry Veteran Kim Deonanan to Lead Its UK and European Sales Efforts

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–News Direct–

News Direct today announced the addition of newswire industry veteran Kim Deonanan to its sales team as European Regional Sales Manager.

Kim Deonanan
Kim Deonanan

Kim previously spent more than 18 years with Business Wire, where she served successfully in roles ranging from UK Sales Manager to Group Vice President, Europe. She will be responsible for business development in the United Kingdom and throughout Western Europe.

Kim brings a wealth of industry experience and significant professional relationships to News Direct and has earned a deep level of respect within the newswire space with colleagues, clients and competitors alike.

I was partly responsible for bringing Kim on board at Business Wire and I came to trust her immensely and admire her greatly for her dedication, professionalism and talent, stated Gregg Castano, Founder and CEO of News Direct and former Business Wire president. She is one of the most knowledgeable people I can think of when it comes to the newswire industry. We are extremely pleased and fortunate to be able to bring someone of her caliber to our team and we're very excited to have her spread the News Direct gospel throughout the UK and Europe.

News Direct is a technology-driven content distribution and amplification platform for PR, IR, corporate communications and marketing professionals. Our automated platform delivers a completely reimagined, modernized user experience for newswire users that has reshaped the industry landscape. Additionally, the company has expanded its offerings to include an array of technology-enhanced message amplification tools ranging from sponsored content to podcasting products, all from one online destination.

Contact Details

News Direct

Gregg Castano

[email protected]

Company Website

http://www.newsdirect.com

View source version on newsdirect.com: https://newsdirect.com/news/news-direct-hires-respected-industry-veteran-kim-deonanan-to-lead-its-uk-and-european-sales-efforts-964547938

News Direct

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COMTEX_441137264/2655/2023-09-28T09:35:58

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Press Release

Supra Completes Over $24m in Early Stage Funding to Date

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  • Supra has raised over $24m in private investment rounds.
  • Supra has received investment from several multi-billion dollar prominent VCs including: Animoca, Coinbase Ventures, HashKey, Prosus Ventures, Razer, United Overseas Bank Venture Management, Valor Equity Partners, among many more.
  • Supra is developing an innovative cross-chain oracle and bridgeless communication network that aims to achieve sub-2 second finality with security guarantees that are projected to be over 10x more secure than incumbent bridges using their bespoke consensus algorithm, Moonshot Consensus.

Supra is helping to facilitate the massive migration of Web2 to Web3 by turbo-charging oracles, cross-chain communication protocols, and their cutting-edge consensus mechanism to build a more secure and interoperable future. There are already over 1.5 million cryptocurrency data pairs being updated daily using Supras next-gen oracle technology.

Over $24m in private investment funding has been accepted from strategic partnerships that recognize Supras game-changing R&D at the cutting edge of the Web3 stack. With several whitepapers spanning 150+ pages in peer-academic review, Supras team of PhDs has been making significant contributions to the body of academic work in secure multi-party computation, decentralized consensus, and blockchain oracles. Leading the way is Dr. Aniket Kate, known best for his work on KZG Polynomial Commitments that underpin Ethereums L2 scaling roadmap, Supras innovations are quickly becoming the new standard for state-of-the-art for oracle protocols.

As for funding, Supra has received support from some of the worlds largest digital asset funds and organizations, including: Animoca Brands, BCW, Coinbase Ventures, FiveT Fintech (formerly Avaloq Ventures), Galaxy Interactive, Hashed, HashKey, Huobi Ventures, No Limit Holdings, Prosus Ventures, Razer.com, Republic Crypto, Shima Capital, Signum Capital, SMO Capital, Sound Ventures, Sublime Ventures, UOB Venture Management (United Overseas Bank), and Valor Equity Partners.

In order to decentralize ownership and governance of the network, over 500 other funds, node operators, and angel investors have been brought in amongst these prominent names to help strategically distribute the token supply. Increasing distribution of their token is critical to the long-term success of Supras decentralized network.

Furthermore, Supra has recently announced a major gamified learn-to-earn airdrop opportunity for community members to further distribute $SUPRA to a wide range of stakeholders. Users can check out their Countdown to Blast Off campaign to join other Supra cadets and learn more. Through their gamified learn-to-earn program, Supra is projected to have over 500,000 KYCd token holders during their Token Generation Event, which is set to occur in early 2024.

Moving forward

Joshua Tobkin, CEO and Co-Founder of Supra, said hes excited to bring Supra to market and give DeFi developers and end consumer a provably fair, high-performance oracle service.

Were very pleased to have achieved the support of some of the biggest names in the blockchain industry, he stated.

Building our network of strategic partnerships is extremely important to our future growth. These partnerships will go a long way towards developing the momentum necessary to bring a much needed security upgrade to the oracle space to further protect DeFi.

Too many people have already been negatively impacted by decentralized finance hacks or exploits, and too much money has been lost. We see our cryptography driven solutions as a way to take speed and security guarantees to the next level, which ensures a higher level of protection for end consumers. We need to level the playing-field and we can't do that until we secure oracles and bridges, which have been the weakest link in Web3. This is an absolute necessity in order for blockchain to achieve its full potential.

Animoca Brands

Yat Siu, the Co-Founder and Chairman of Animoca Brands, commented: Oracles are an important link bridging data portability and interoperability across different networks, and were therefore thrilled to support Supra as one of the projects developing the essential technological basis for a truly open metaverse.

Republic

Alex Ye of Republic Advisory said: "The crypto industry had not committed to solving the oracle problem until Supra played the patient game and did their research on L1 consensus for oracles. While others might have come first to market, they all end up delaying the inevitable that Supra now fulfills. Oracles are both the key to cross-chain infrastructure, whether that comes from on-chain or off-chain data. Supra is the key that unlocks the real potential of cross-chain liquidity, multi-chain web3 applications, and more. I fully expect Supra to be the brand name internet infrastructure among traditional financial institutions and Web3 developers as synonymous as AWS, IBM, and Google in the Web2 world."

Hashed

A spokesperson for Hashed said: Oracles are currently the single most utilized vector for exploits, and its crucial for the industry as a whole to experiment with different trade-offs to improve this crucial infrastructure. Were excited to be a part of Supras journey as their approach to advancing speed and security with sophisticated randomness will be a great addition to the collective intelligence of Web3. Supra has the potential to open up use cases that were implausible before by redefining liveliness of oracle feeds, and we will be dedicated to exploring new boundaries with the team.

Sound Ventures

Maaria Bajwa, blockchain investor at Ashton Kutcher and Guy Osearys Sound Ventures, said: Supra and its incredible team have spent the last few years building a powerful oracle that has the flexibility and usability to scale with this ecosystem as it continues to accelerate in growth. Its node architecture ensures better security than existing oracles, while still processing information at faster speeds. Faster speed is critical to driving Web 3.0 closer to real-time transactions and replacing legacy systems. With a powerful oracle like Supra, DeFi users will now be able to easily offer loans across multiple chains and currencies, thereby expanding the market opportunity in DeFi. And all of this at a cheaper cost for developers and a better environmental footprint.

Prosus Ventures

A spokesperson for Prosus Ventures said: As DeFi use cases expand and scale, new multi-chain oracle solutions will need to come to market. We believe Supras technology will be a key component of the Web3.0 DeFi ecosystem, significantly increasing transaction finality to mere seconds, while improving security and enabling cross-chain interoperability. What is also apparent to us is the teams deep understanding of this space, and were confident in their leadership and roadmap to achieve what no other oracle solution has yet been able to accomplish technically.

Huobi Ventures

A spokesperson for Huobi said: "Huobi Ventures is thrilled to invest in Supra as they create and build the next-generation oracle infrastructure. We believe their seasoned team of highly experienced professionals will deliver a best in class oracle solution that improves upon the performance and security of existing oracles, and provides a premium product for users. Combining the founding teams extensive experience with their long-term vision, we look forward to supporting this ambitious organization."

FiveT Ventures

A spokesperson at FiveT Ventures (formerly Avaloq Ventures) said: "FiveT Fintech, an early-stage investor in web3 and financial services infrastructure working closely with Avaloqs ecosystem consisting of over 150 financial institutions, is proud to participate in Supras strategic financing round. We see a growing need for verified off-chain data and are convinced that Supras ability to operate in such a fast, reliable, and highly decentralized way will enable new game-changing applications. Getting to know Supras team, we were impressed with their profound knowledge and fast-paced execution skills. For FiveT Fintech, Supra marks an important additional piece to complement our strategic investments in crucial web3 infrastructure and we are excited for close collaboration within our ecosystem."

HashKey

Harper Li, Investment Manager at Hashkey Capital, said: Supra is positioned as an IntraLayer with native oracle, native VRF, and native automation. Native oracle is the earliest product, which has been tested on more than 20 testnets. Native VRF combined with DKG technology solves the problem of public output and latency in this field compared with other random number solutions. In the future, the development of native automation will be introduced into the on-chain automatic execution, while the combination of on-chain automatic execution and the abstract account has a lot of imagination space.

Sublime Ventures

Musthafa Ahmed, General Partner at Sublime Ventures, said: "What started out as a mission to create a next-gen, decentralized cross-chain oracle solution, has evolved into so much more. Perfectly primed to set the gold standard as Web3's first intralayer solution, Supra is on track to dominate the industry with their superior and unparalleled tech stack, whilst also acting as the backbone unifying all major ecosystems in the sector."

About Supra

Supra is building a low-latency interoperability infrastructure to provide Web3 capabilities that traditional blockchain designs lack. Supra, as a vertically integrated IntraLayer, enables a shared security paradigm across a variety of oracle services. This includes securing external data on-chain, cross-chain consensus via their bridgeless HyperNova, automation, VRF, and more.

After thousands of hours of R&D and simulations, Supras technical breakthroughs are solving the Oracle Dilemma and optimizing network performance across the board in terms of security, throughput, time to finality, composability, and programmability. Supra has taken an academic approach to development, which has been an integral part of the organizations commitment to advancing Web3 performance and security. This is characterized by a commitment to deep research, transparency, and going through a rigorous peer-review process in every design and product released.

Dr. Aniket Kate, inventor of KZG Commitments utilized in Ethereum L2 Data Availability solutions, and the Supra team are diligently composing new whitepapers, so there are still many novel solutions in the pipeline soon to be publicized. To learn more about Supra and participate in their gamified learn-to-earn program, visit Countdown to Blastoff. Lastly, sign up for the whitelist for an opportunity to be notified in advance of any possible future token offerings and for more alpha.

Contact Details

Supra

Eli Phoenix

[email protected]

Company Website

https://supraoracles.com/

View source version on newsdirect.com: https://newsdirect.com/news/supra-completes-over-24m-in-early-stage-funding-to-date-847591291

Supra

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COMTEX_441137828/2655/2023-09-28T09:44:41

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Press Release

The Experienced Divorce Lawyers at Davalos Law Firm PC Expand their Premier Family Law Services to Tracy CA

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Tracy, CA – Davalos Law Firm PC is thrilled to announce the expansion of its family law services to Tracy, CA. With a dedicated team of experienced family law attorneys, the law firm is now ready to assist clients in the area in navigating the complexities of family law matters including divorce, custody disputes, child support, prenuptial agreements, adoption, and other related legal issues.

The process at Davalos Law Firm PC consists of several essential steps that ensure comprehensive and effective representation for clients facing family-related issues. During the intake process, the firm’s team, led by attorney Brian Davalos, conducts a thorough assessment of each client’s goals, urgent issues, court dates, and deadlines. This allows them to gain a comprehensive understanding of the client’s situation and to offer a tailored retainer agreement.

Once the intake process is complete, Divorce Attorney Tracy CA proceeds to the strategy phase. Here, the client’s goals are identified, and the strengths and weaknesses of the case are carefully categorized. A detailed timeline of events is established, serving as the roadmap for the firm’s strategic approach to the case, whether it involves an attack or a defense.

With a solid strategy in place, Davalos Law Firm PC moves on to the implementation phase. During this stage, the firm drafts and serves necessary pleadings while establishing contact with opposing parties to develop a rapport and set boundaries. Its attorneys create a comprehensive discovery plan, ensuring that all relevant evidence is obtained within designated deadlines. The attorneys also anticipate potential issues or special motions that may arise during the litigation process.

As the case progresses, Davalos Law Firm PC seeks out all discoverable evidence to strengthen the client’s position. Through the use of subpoenas, depositions, requests for inspection, and other discovery methods, the firm amplifies its litigation strategy to align with the client’s desired goals. The law firm thereafter proposes alternatives to trial during the settlement conference stage. Judicial arbitration or mediation may be suggested as viable options to avoid the uncertainty of trial.

Should the case proceed to trial, Divorce Lawyers Tracy CA diligently prepare for this critical stage. The attorneys engage in thorough client meetings, review all discovery and evidence, and conduct mock scenarios to ensure the client is well-prepared and capable of handling high-stress situations. These professionals zealously advocate on behalf of their clients, seeking favorable judgment and striving for a strong finish.

At the core of Davalos Law Firm PC’s approach is a dedication to open communication, transparency, and accessibility. The firm places a strong emphasis on keeping clients well-informed, empowering them to make informed decisions, and providing guidance to stay ahead of their adversaries. Clients can expect prompt responses to their messages, emails, and texts, ensuring they remain engaged and supported throughout the entirety of their cases.

The expansion of Davalos Law Firm PC’s services to Tracy, CA, brings its award-winning process to individuals and families in need of exceptional legal representation. The firm aims to create a positive impact within the community by helping its clients navigate family law matters with confidence and achieve favorable outcomes.

To schedule a consultation, contact their team at (209) 207-0598 or visit the firm’s website for more information regarding the services offered.

Media Contact

Company Name
Davalos Law Firm PC
Contact Name
Brian Davalos
Phone
209-207-0598
City
Tracy
State
CA
Postal Code
95376
Country
United States
Website
https://thedavaloslawfirm.com/

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